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Doctor insights on: Lyme Disease Inconclusive Test Results

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Dr. Randy Baker
623 doctors shared insights

Lyme Disease (Definition)

Lyme is caused by borrelia burgdorferi. Acute symptoms can include bullseye rash, headaches, joint pain, fever, and flu like sx. Chronic symptoms can include fibromyalgia symptoms, nerve pain in extremities, mood swings, brain fog, heart problems. Lab diagnosis is not very reliable, and sometimes clinical ...Read more


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Can you have Lyme disease and still have a negative test result on the western blot test?

Can you have Lyme disease and still have a negative test result on the western blot test?

Possible: Lab tests have false negatives and false positives. Each lab test result needs to be interpreted in the clinical context. A person may have infection with lyme disease and may not make appropriate antibody and have a negative test while the test is working properly. ...Read more

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I had a blood test (Western Blot), to check for Lyme Disease. The results look strange (0.45). This doesn't look like the result of any WB test I have?

I had a blood test (Western Blot), to check for Lyme Disease. The results look strange (0.45). This doesn't look like the result of any WB test I have?

Probably not Lyme: Your Western Blot would need to be above 5 for a conclusive confirmation of Lyme disease. Unless you also had known tick bite, low-grade fever, "erythema migrants", you probably had a viral illness that should resolve on its own. Do discuss this with your primary medical provider or specialist if symptoms persist. ...Read more

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Lyme disease ab plus reflex to igg, igm-wb blood test done today. How long for results and how accurate are they?

Lyme disease ab plus reflex to igg, igm-wb blood test done today. How long for results and how accurate are they?

About a week: The regular lyme test is specific but not very sensitive .There can be many reasons for a false positive result. If it is positive on the screening test it is then sent for the more sensitive western blot test. If the igm test is positive it could represent a recent exposure to lyme disease if the igg is positive it indicates a more distant orast exposure. If the igm is positive you should be eval. ...Read more

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Could i test negative for Lyme disease but actually had it?

Only: If you recently been bitten by the tick, or where profoundly immunosuppressed. ...Read more

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Low cd57 and Lyme disease? Are these tests some method of detecting Lyme disease?

Contorversial: Cd57 testing is a controversial way of trying to determine if someone has lyme disease. It is not widely accepted as accurate and most clinicians do not test for it. ...Read more

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What is the single best test for Lyme disease?

What is the single best test for Lyme disease?

Possibly new culture: There are many tests for lyme, but none are totally reliable. The elisa test is positive in about half of those infected. The western blot test is positive in ~70% of cases, but most labs don't do a thorough enough version- i recommend igenex labs. Pcr tests are positive only ~20% of the time. A new test, a culture by advanced laboratory services may detect lyme in >80% of cases so may be best. ...Read more

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