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Doctor insights on: Lyme Disease Ig M Positive

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Igm is negative but IgG is positive for Lyme disease, what to do?

Igm is negative but IgG is positive for Lyme disease, what to do?

Old Infection: This most likely means you had an old infection with lyme disease. Our bodies make IgM early in an infection and IgG later. Even once the infection is gone there will be detectable IgG for quite some time. This is part of how our body remembers previous infections so we can fight them off better if we get them again.

Dr. Randy Baker
644 Doctors shared insights

Lyme Disease (Definition)

A condition caused by borrelia burgdorferi. Acute symptoms can include bullseye rash, headaches, joint pain, fever, and flu-like sx. Chronic symptoms can include fibromyalgia symptoms, nerve pain in extremities, mood swings, brain fog, heart problems. Lab diagnoses are not very reliable, and sometimes clinical ...Read more


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Tested positive for Lyme disease IgM but my western blot test came back negtive?

Tested positive for Lyme disease IgM but my western blot test came back negtive?

Then it's not Lyme: Lyme disease can be tricky -and you want to make sure you see someone like an Infectious Diseases doctor who knows how to treat it. The diagnosis is actually based on clinical findings, and the lab testing is generally 'supportive'. Since you're Western blot is negative, then it's very unlikely you have Lyme. There are other diseases that could cause 'Lyme-like' symptoms -and good to get evaluated

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How long could the IgG in Lyme disease stay positive? Could it stay positive more than 5-10 years? I know the IgM ab convert to IgG just want an answer

How long could the IgG in Lyme disease stay positive? Could it stay positive more than 5-10 years? I know the IgM ab convert to IgG just want an answer

Yes, positive 20+ yrs: Research suggests igg antibodies can persist at least 20 years after infection. While igm antibodies appear first, unlike other infections they often persist ; are a good indicator of persistent infection. One may have chronic lyme with or without persistence of igg antibodies. Chronic lyme is difficult to fully eradicate ; no current test proves that it is no longer present in your body!

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I tested positive for Lyme disease. I was given the EIA (result 6.1), IgG (10 bands present) and IgM WB (3 bands) Does this mean I've had LD for a whi?

I tested positive for Lyme disease. I was given the EIA (result 6.1), IgG (10 bands present) and IgM WB (3 bands) Does this mean I've had LD for a whi?

Yes: The presence of IgG usually indicates past infection which might have occurred months or even years ago. The presence of IgM indicates a current or recent infection.

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Could I have Lyme disease? Not posible its recent. Borrelia Oct 14 IgM = 1.00 (1-1.5 inconclusive), Jan 15 IgM = 1.53 (1.5+pos) IgG = 0.16 (<1.00neg)

Could I have Lyme disease? Not posible its recent. Borrelia Oct 14 IgM = 1.00 (1-1.5 inconclusive), Jan 15 IgM = 1.53 (1.5+pos) IgG = 0.16 (<1.00neg)

See details: The lab results sre unimpressive. I strongly doubt Lyme disease based on your lab results. Without your symptoms and results of a Western blot it is impossible to answer. I

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Was test for Lyme disease and test seem to be normal except for igm is 1.32 high and igm p23 present all else says absent, does this mean I have Lyme?

Infected yes: Elevated IgM points to recent or current infection. Whether you do have Lyme Disease or not will need further observation. For example, have you seen any target like lesion yet?

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Why would my lyme disease western blot test show 4 igg bands as reactive? Could this mean I have the disease? None of the igm bands were reactive.

Why would my lyme disease western blot test show 4 igg bands as reactive? Could this mean I have the disease? None of the igm bands were reactive.

Not necessarily: IgM antibody means recent infection. IgG antibody usually means remote infection. You may not have the disease, just that you may have been infected at one time.

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"p23 ab IgM reactive" "p41 & p39 non-reactive" do I have Lyme disease, or can something else cause this? (diagnosed w/ rheumatoid arthritis 7yrs ago.)

"p23 ab IgM reactive" "p41 & p39 non-reactive" do I have Lyme disease, or can something else cause this? (diagnosed w/ rheumatoid arthritis 7yrs ago.)

Complex: The diagnosis of lyme disease is usually on a clinical basis. Serologic testing should not be done for screening purposes. False positive results are very frequent in patients with autoimmune diseases, particularly rheumatoid arthritis, and particularly when these are IgM antibodies.

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Lyme disease ab plus reflex to igg, igm-wb blood test done today. How long for results and how accurate are they?

About a week: The regular lyme test is specific but not very sensitive. There can be many reasons for a false positive result. If it is positive on the screening test it is then sent for the more sensitive western blot test. If the igm test is positive it could represent a recent exposure to lyme disease if the igg is positive it indicates a more distant orast exposure. If the igm is positive you should be eval.

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I tested positive for Lyme disease in 6?

I tested positive for Lyme disease in 6?

Need more info: So what is your question? One needs to know your symptoms and which 6 bands were positive. It may or may not have any significance.

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Can a positive Lyme disease western blot strip test be mistaken for another disease?

Can a positive Lyme disease western blot strip test be mistaken for another disease?

Yes!: No lab test is perfect, including the westen blot for lyme. There is an approximately 4% chance of a positive being a "false positive" test. There is also an approximately 20% chance of false negatives, someone with lyme not having a positive western blot. This is why lyme is ultimately a clinical diagnosis, with labs used to support a diagnosis. Other tests may also be useful. Please see comment:.

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Dr called with a "not 100% sure but positive you have Lyme disease" diagnosis from bloodwork. How is this possible?

Difficult diagnosis: I agree that "not 100% sure" and "positive" are in conflict; you'll have to clarify with the doctor. However, diagnosing Lyme disease by blood test can be difficult; the available tests are notoriously unreliable. For these reasons, Lyme is often blamed for nonspecific sypmtoms caused by other things. Before getting into prolonged Rx, request consultation with an infectious disease specialist.

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How can someone test positive for two Lyme-specific bands on western blot and NOT have been exposed to Lyme disease? What is magic about 5 bands?

Immune complexities: Lyme disease is caused by a certain type of bacteria called a 'spirochete'- they are a whole class actually of bacteria and believe it or not can be found commonly in the mouth or elsewhere in the environment. You have to reach a certain 'threshold' with Lyme testing because there could be some cross-reactivity coming from these other types of bacteria. The immune system is extraordinarily complex

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I got a Lyme disease test done.& IgG 66 came positive out of the other 10 bands. What does this mean? Do I have Lyme or had it? Should I worry? Thanks

Not enough info: This test is not evidence of lyme but also not proof you don't have it! Ultimately lyme is a clinical diagnosis. 20-30% of those who have it never have a positive western blot. It's really important that the test include the 31 & 34 bands & most labs don't check it- igenex is the best lab for a thorough test. See a doc who uses igenex as that is someone able to make a proper diagnosis. See comment:.

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What makes it unknown if chronic Lyme disease is real or not? I just tested positive for past infection and have gone unbelievably downhill since bite

Need more info: "chronic" lyme disease is difficult to diagnose because isolation of the organism has not been effected and the serologic tests used can be misinterpreted. Many doctors feel that these symptoms are the result of some immune process, but the details have been resistant to definitive diagnosis or understanding. To know what you have you need to see a doctor, preferably id.

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What to do if I did a Lyme disease test and it showed IgG p58 ab. Positive a can you explain what that means?

Nothing by itself: A single positive IgG band means nothing. Was the screen positive? How many other IgG and IgM bands were positive? You should discuss all of this with the doctor who ordered the test.

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Dr said he suspects I've had Lyme disease untreated for 5 years. He will test soon, if positive, what's the treatment? Antibiotics?

Lyme disease: 3 points. Lyme does not show up with serological testing in most cases. Lyme passes 100% of the time between significant others, so have your partner checked and treated. There are 4 components to treating Lyme. Doxy Monohydrate for the Spirochete. Identify and treat accompanying parasites with Systemic Formulas' VRM herbal products. Identify and treat co-infections. Treat biotoxins c cholorell

Dr. Gregory Lanza
820 Doctors shared insights

Immunoglobulin M (Definition)

There are 5 classes of immune proteins: igg, iga, igm, ige and igd. Igm fights infection. If you produce too little then infections may occur and you have hypogammaglobulinemia. If you have too much you ...Read more