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Doctor insights on: Lyme Antibody Negative Ig G Positive

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what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

Recent infection: Hi. IgM is present only with recent infection. After IgM levels fall away, IgG takes over for ongoing and recurrent exposure to antigen. (The antibodies in this picture are IgG's). I'm glad your doc was on the ball. She/he may have saved you a world of hurt by making the diagnosis promptly. Good luck! ...Read more

Dr. Randy Baker
623 doctors shared insights

Lyme Disease (Definition)

Lyme is caused by borrelia burgdorferi. Acute symptoms can include bullseye rash, headaches, joint pain, fever, and flu like sx. Chronic symptoms can include fibromyalgia symptoms, nerve pain in extremities, mood swings, brain fog, heart problems. Lab diagnosis is not very reliable, and sometimes clinical ...Read more


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If I am on antibiotic and an acne gel, can that affect or cause false results on a toxoplasma IgG test or a Lyme IgG test?

If I am on antibiotic and an acne gel, can that affect or cause false results on a toxoplasma IgG test or a Lyme IgG test?

No, meds won't do it: Ninety percent of us have been exposed to Toxoplasma, so it's no surprise your IgG test for that is positive. No worries there. With Lyme IgGs it depends on 'what bands' may or may not be positive. You would need at least 5 bands on the IgG test to be considered a positive, but then that needs to be interpreted in the right clinical context. Ur meds aren't at fault. Good to check back with ur doc. ...Read more

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Igm is negative but IgG is positive for Lyme disease, what to do?

Igm is negative but IgG is positive for Lyme disease, what to do?

Old Infection: This most likely means you had an old infection with lyme disease. Our bodies make IgM early in an infection and IgG later. Even once the infection is gone there will be detectable IgG for quite some time. This is part of how our body remembers previous infections so we can fight them off better if we get them again. ...Read more

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Is it possible to have a Lyme infection with a negative IgG but positive igm?

Is it possible to have a Lyme infection with a negative IgG but positive igm?

Yes: Igm is the immunoglobulin noted for coming out early in response to any illness, it fades over time while igg come out a bit later and stays up longer. If you have a positive IgM it indicates a early response, while igg would probably show up in a few months at which point the IgM would have declined. ...Read more

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Lyme,Total AbTest/Reflex.Lyme IgG/IgM Ab < 0.91;Reference Interval:ISR 0.00-0.90; negative <0.91;equivocal 0.91-1.09;positive >1.09.Is above + or equi

Lyme,Total AbTest/Reflex.Lyme IgG/IgM Ab < 0.91;Reference Interval:ISR 0.00-0.90; negative <0.91;equivocal 0.91-1.09;positive >1.09.Is above + or equi

Negative: If a patient's lab test result is <0.91, and the lab says the reference range for NEGATIVE is <0.91, then the test result is NEGATIVE. Of course, numbers are just numbers, so the doctor needs to see the numbers in the context of the whole patient in order to make sensible and accurate conclusions from the numbers. ...Read more

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Is an IgG positive Lyme test a risk?

Lyme disease: Lyme diagnosis is made on one's history, exposure to tick that carry lyme disease in the setting of typical signs and symptoms . If a doctor confirms the typical bulls-eye rash lab testing is not required for diagnosis. Igb g positive indicates potential infection with lyme disease and may be present even after the infection has resolved and should be utilized in conjunction with clinical featue. ...Read more

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I got a Lyme disease test done.& IgG 66 came positive out of the other 10 bands. What does this mean? Do I have Lyme or had it? Should i worry? Thanks

Not enough info: This test is not evidence of lyme but also not proof you don't have it! ultimately lyme is a clinical diagnosis. 20-30% of those who have it never have a positive western blot. It's really important that the test include the 31 & 34 bands & most labs don't check it- igenex is the best lab for a thorough test. See a doc who uses igenex as that is someone able to make a proper diagnosis.See comment:. ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more