Doctor insights on:
Lutrepulse Gnrh Stimulator
FSH,LH: Gnrh stimulates follicle stimulating hormone & luteinizing hormone which stimulates the ovary to produce estrogen and Progesterone which stimulates ovulation which causes increased Progesterone which causes secretory endometrium which prepares the endometrium to allow implantation of a fertilized egg. If no fertilized egg, Progesterone falls which stimulates gnrh to again rise & the cycle repeats. ...Read more
Good question: Gnrh would seem by its name to help release gonadotropin. And if used in a certain fashion it could cause the release of gonadotropins (lh, fsh). However when given in a shot and having a sustained effect on the pituitary, it actually suppresses the release of lh and fsh. And this aspect of the medication can be used to help in many situations. ...Read more
Please resubmit: Can you please be more specific with your question? It's not clear if you are asking whether you need a followup, or with whom, or have other questions. Please contact the doctor who implanted the stimulator if you have specific questions about your procedure, and YES, you need followup afterwards. ...Read more
Her how it works: The g protein-coupled, seven-pass transmembrane molecule present in the parathyroid gland and kidney controls calcium homeostasis by releasing parathyroid hormone (pth). Manipulating calcium-sensing receptor (casr) using small-molecule allosteric modulators can affect PTH secretion. ...Read more
No: At this time, there is no evidence to suggest this. As one may imagine, few if any studies have been performed in humans to look for this. ...Read more
Insulin: GnRH is stimulated by an increase in insulin (as can be seen in PCOS). An increase in prolactin causes a decrease in GnRH. GnRH is low in early childhood, then is activated in puberty, and has a pulsatile release for normal reproductive function. What exactly initiates puberty is not completely known with biological and environmental factors playing a role. ...Read more
1998 journal article:bodybuilders testicular function permanently restored by 3month HCG. By what mechanism? Isnt HCG suppressive of lh?
1998: A 1998 journal is a bit outdated. If you testosterone is normal - have you had it measured - it is unwise to take any extra T. If your testosterone is low, or you think it is, please see your doctor who will take your history, examine you, and order labs. By now you must know the problems super athletes get if they continue taking excess testosterone. ...Read more
Clomid (clomiphene) is an estro receptor.Brain needs estrogen surge to release lh.Which means ppl on Clomid (clomiphene) don't have LH surge?How egg burst out?
Got confused?: You are getting yourself confused. Clomid (clomiphene) is not an 'estro receptor' at all; it is mainly an estrogen receptor antagonist, but it has pro-estrogenic actions in some tissues and anti-estrogenic actions in others. Women on Clomiphene do mostly have an lh surge; not surging means the Clomiphene dose was likely too low. ...Read more
Unlikely: Generally no, not pain unless you mean pain at the injection site. ...Read more
After 5dys IVF therapy (1 Cetrotide 0,25mg&1 Fostimone daily) I stopped it due to the follicle small growth. Why small growth beside stimulation?
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Would using Dihydrotestosterone (DHT)blockers like an Antiandrogen to block DHT's from affecting hair follicle growth have unpleasant side effects?
Risk vs benefits: Infection is the #1 risk which is less than 4% per 2004 study in journal neurosurgery spine. Less common risks include bleeding, nerve irritation/damage, allergic reaction, hardware malfunction, pain at implant site, dysesthesias, and spinal headache. The risks are fairly low in the hands of an experienced physician, and the benefits can be great. Talk to your doc about details. ...Read more
Is there a drug like Clomid (clomiphene) that trick hypotalamous you have low testosterone and stimulate lh?
Its no trick: Clomid (clomiphene) as well as other aromatase inhibitors block estrogen receptors in the pituitary, causing the release of LH. In women, this helps with ovulation (egg production), in men it can raise testosterone levels. However, at age 16, you should not be using these medications unless under the guidance of an endocrinologist. ...Read more