Doctor insights on:
Lutrepulse Gnrh Stimulator
GnRH hormones: While normally gnrh stimulates sex hormones, it achieves this only when it is secreted in bursts by the hypothalamus. When given in injections, it circulates continuously and it suppresses the hormones that in turn stimulate the ovary in women and the testes in men. As a consequence, there is a lack of sex hormones (estradiol in women, testosterone in men, leading to bone loss as in menopause. ...Read moreSee 1 more doctor answer
Why do FSH levels rise around day 14 of the cycle? Is it just because of the higher GnRH that cause the LH surge?
You asked...: FSH rises because 1) it induces expression of its own receptor and 2) it stimulates E2 production, which also induces expression of more FSH receptors. GnRH is not "higher" or lower, GnRH is pulsatile: the frequency of the pulses is as important (or more) than the pulse amplitude. If this unclear, I suggest consulting an endocrinology text, there is no short version. ...Read moreSee 1 more doctor answer
FSH,LH: Gnrh stimulates follicle stimulating hormone & luteinizing hormone which stimulates the ovary to produce estrogen and Progesterone which stimulates ovulation which causes increased Progesterone which causes secretory endometrium which prepares the endometrium to allow implantation of a fertilized egg. If no fertilized egg, Progesterone falls which stimulates gnrh to again rise & the cycle repeats. ...Read more
Yes: Testosterone (from the testicles) and gnrh (from the hypothalamus) are connected by a feedback mechanism much like the thermostat in one's house. When testosterone levels rise for whatever reason, the hypothalamus decreases its release of gnrh to help bring t back to normal levels and vice versa. ...Read moreSee 1 more doctor answer
Unlikely: Generally no, not pain unless you mean pain at the injection site. ...Read more