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Doctor insights on: Lupus Versus Mixed Connective Tissue Disease

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Labs are coming back suggestive of Lupus or Mixed Connective Tissue Disease. What is the difference between the two?

Labs are coming back suggestive of Lupus or Mixed Connective Tissue Disease. What is the difference between the two?

Mystery of....: rheumatology! Lupus difficult to diagnose because of many manifestations and wide range of severity. No clear diagnostic criteria. Diagnosis made on clinical grounds with supporting labs- requires a great deal of expertise and exclusion of other causes for symptoms. If your doc cannot confidently diagnose lupus then you may be given an alternative Dx such as MCTD or undifferentiated CTD. ...Read more

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Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


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Does kidney stones go along with having lupus and mixed connective tissue disease?

Does kidney stones go along with having lupus and mixed connective tissue disease?

No, ....: To find and establish a connection of a disease with others is essential in medical care with a mind of prevention, but not easy. In the case of kidney stone with le, I have exhausted my recollection of studies, articles, professional meeting and discussion over my 45-yr study and practice in urology, but I have never come across such concern that you raised. So, i would say "no." for now. ...Read more

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Whats the difference between connective tissue disease and lupus?

Whats the difference between connective tissue disease and lupus?

Not the same.: Systemic lupus is one of the so called "connective tissue diseases, " which includes many other diseases, some related to sle, and other's which are not. The term connective tissue disease more broadly means autimmune disease and the term is somewhat antiquated! ...Read more

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How would I be diagnosed with a connective tissue disease (lupus)?

Symptoms and test: To diagnose lupus you need certain combination of symptoms and positive blood test, very typical symptoms oflupus are "butterfly rash" over the nose, join pain/swelling, oral sores, eyes symptoms, lupus can also give lung, heart, kidneys involvment, blood with anemia, low WBC counts. Blood test that can be positive in lupus is ANA (95% patient), anti-dsdna, also blood and urine testing may suggest. ...Read more

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Could undifferentiated connective tissue disease (poss sjogrens +\or lupus) cause increased feeling of being winded when it is humid outside?

Could undifferentiated connective tissue disease (poss sjogrens +\or lupus) cause increased feeling of being winded when it is humid outside?

Difficult question: And one that probably can not be answered on this sit specific to you. Some kinds of connective tissue diseases can cause constriction and make you feel short of breath, others not. It is vert variable. The ones you mentioned probably not ...Read more

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How does connective tissue disease with lupus factor affect the eyes?

How does connective tissue disease with lupus factor affect the eyes?

In several ways!: Lupus can be associated with dry-eye syndrome, typically more severe in sjogren's syndrome. Very severe lupus can causes optic neuritis, but this is quite rare. The most common problem with the eye in lupus patients is the development of cataracts from treatment with steroids, one of many reasons doses should be kept low. Plaquenyl eye toxicity is nill, by using less than 6 mg/kg of body weight. ...Read more

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Connective Tissue (Definition)

There are many types of connective tissue, but in general it is a mass of fibers and thick "goopy" fluids secreted by specialized cells. The body often uses connective tissue to help ...Read more