Doctor insights on:
Lupus Online Test
Probably not lupus: Many people have symptoms suggestive of lupus but most turn out not to have the disease. The ANA and other blood tests are virtually always positive in patients with lupus. Negative tests mean you're not likely to have lupus. A bigger problem is false positive anas, in which case the teat is positive but the patient does not meed other diagnostic criteria to lupus. ...Read more
TESTS FOR LUPUS:
Cbc, urine and sed rare. Following test are important to diagnose lups
1ana titer is an important test, it is positive in 97%of patients with lupus. When threeor more typical features of lupus are present like, skin, joints, kidneys, lungs, heart, blood or nervous system, positive ANA will confirm it
2anti ds dna +iin half patients
3apls antibody+in 30%
4ro/ss-a and la/ss-b in skin lupus
sm antibod 30-40%. ...Read more
Lupus: There are different tests for lupus. Diagnostic tests which can be positive even if you don't have a flare. Then there are test to determine disease activity which can be abnormal during flares. Mind you that a diagnosis of lupus depends on history, clinical exam in addition to lab. Best wishes ...Read more
Yes: Yes you can.Get a more detailed answer ›
Need further test: False positive RPR may suggest antibodies in the blood that is cross reacting with RPR test reagent. Common antibodies are antiphospholipid antibodies that gives false positive RPR. Lupus is diagnosed based on signs and symptoms PLUS presence of ANA antibodies in the blood. You can ask your MD to check for these antibodies by blood tests. ...Read more
Exam is best: The sores with pale center and dark rim, uneven scales / crusts are usually easy to diagnose on physical exam by a general physician; any dermatologist can make the call easily. If there is doubt, punch biopsy shows distinctive features to the pathologist that will remove any doubt; both a standard stain and a "lupus band test" may be performed. Dle is usually manageable but not curable. ...Read more
Not 100 %: There re several tests for lupus ana, double stranded dna and none of these tests is 100 per cent reliable for the diagnosis of lupus. A similar situation occurs in rheumatoid arthritis where there seedless negatives as well as false positives. If there is akin involvement a skin biopsy for direct exam as well as immunoflourescence can help with diagnosis. ...Read more
See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, a monocyte count of 156 is not a cause for concern. ...Read more
Is it possible to have lupus but come back negative on the test or is the test the only way to tell?
The test may be negative in early LUPUS and may give false POSITIVES as well...
No test is 100% "foolproof"
ANTI-NUCLEAR antibodies and if positive a certain TYPE of anti-nuclear response may be helpful!
Hope this info helps!
Dr Z ...Read more
Is there a quick, simple test I can have at the doctors for Lupus - having a few symptoms of it over the years?
No: A diagnosis of Lupus is made with a combination of blood tests and symptoms. There is not one simple test that will tell you for sure. ...Read more
Had a lupus test done and everything was normal except my thrombin time with a little high at 22.8 is this serious?
By itself, no: E by itself, no. Depends if there is evidence for any system involvement ...Read more
I'm from the state of Wyoming & have Lupus. My tests while living there were very high. Now live in Michigan & all come back Negative is this normal?
Unusual: However it is theoretically possible if you had far more sun exposure in Wyoming than in Michigan given that sunlight can induce LE. On the other hand, your problem may be from another autoimmune disease. If you are feeling well otherwise, no test is needed. But if you do have symptoms then I would suggest repeating the test in case there was a blood sample mix-up. ...Read more
Not really: The diagnosis is made based on symptoms, physical exam findings and some blood work. People frequently refer to some of the antibodies checked in lupus as "lupus tests" but just because the test is positive does not mean you have lupus. Less than 1/2 the patients I see for a "positive lupus test" end up having lupus. ...Read more
Anti-nuclear antibody test (ANA) to determine if autoantibodies to cell nuclei are present in the blood.
Anti-dna antibody test to determine if there are antibodies to the genetic material in the cell.
Anti-smith antibody test to determine if there are antibodies to sm, which is a ribonucleoprotein found in the cell nucleus. ...Read more
Spectrum of things: Lupus is diagnosed through a spectrum of findings and not just a blood test. Blood tests help us, but are certainly not the end all be all. There are cases where people have lupus wih negative blood tests. ...Read more
It depends: Lupus has many different symptoms. There are varieties of lupus limited to the skin. In these types, the ANA can be negative. However there are more severe forms of lupus, that can effect almost any part of the body. Commonly effected organs include the joints, kidneys, lungs, brain, and blood vessels. In these forms of lupus, the ANA test is almost always positive ...Read more