Doctor insights on:
Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read moreSee 1 more doctor answer
How/why can lupus symptoms present & diagnosis of lupus be made by clinical picture &high ANA titer only?Why don't other labs show positive?Two rheum mds dx'd me.
Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.
Maybe: ANA positive diseases are related. Diagnosis is based not just on serologic testing, but also on your clinical symptoms. You should be evaluated by a rheumatologist in order to receive an accurate diagnosis and then receive the most appropriate treatment. ...Read moreSee 1 more doctor answer
Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read moreSee 1 more doctor answer
1280 ANA, -ENA and compliments. lupus symptoms, but rheum said no lupus because I have Blau Syndrome, rare autoinflammatory, doesn't cause ANA. Help!
Talk to your MD: Blau syndrome, systemic granulomatous syndrome, is a rare autoimmune disease affecting many organs. It can simulate, at least initially, other autoimmune diseases. There is effective treatment for most patients with the disease. Either talk with your rheumatologist or go to a tertiary medical center. ...Read more
Labs,imaging, biopsy: Lupus and sarcoidosis affects many organs and both can have similar symptoms.However doctor(rheumatologist) can differentiate these two diseases by various blood tests, imaging and sometimes biopsy - skin, liver and kidney depending on the organ involved.So the diagnosis is often clear, raraly misdiagnosed. The diagnosis must be confirmed as the treatment options are quite different. ...Read more
Ana direct positive ANA , ifa neg , rnp 2.3, CRP 5.4 ss-b2.7.Diag with lupus connective tissue and sjorgen all at once? Why 2 ANA tests different answ
They can change!: Appears you have mctd with sjogren's like features based on the labs and titers. No lupus marker present! ...Read more
Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read moreSee 1 more doctor answer
Autoimmune symptoms (fatigue, joint/muscle pain, headaches, gastro issues, etc.)Tested for lupus. RNP was 2.5. No lupus. Rheum said restest. Thoughts?
Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read moreSee 1 more doctor answer
Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more
- Talk to a doctor live online for free
- Misdiagnosis of ibs
- Misdiagnosis of schizophrenia
- Ask a doctor a question free online
- Misdiagnosis of herpes
- Misdiagnosis of shingles
- Multiple sclerosis misdiagnosis
- Ectopic pregnancy misdiagnosis
- Talk to a rheumatologist online for free