Doctor insights on:
Lupus Like Anticoagulating Molecule
Have common variable immune deficiency, and rheumy thinking lupus. Just checked complement system and c1q binding assay came back high? Lupus? Other
Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?
Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?
Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more
Developed anca positive vasculitis with antihistone ab 1.4 after 2 months on losartan 50. disc reversedanemia. is angiogenesis critical 4 vasculitis?
This is more than o: Thisis more than one answer. The histone ab is seen in lupus and drug induced lupus. ANCA positivity can mean a variety of issue related to vasculitis but other conditions also, Uncertin about you commetn on anemia. Angigenesis is usually part of a variety of conditions including vasculitis but is seen in non-vaculitis syndromes also. Would advise you disucss this with your rheumatologis ...Read more
Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?
Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read moreSee 1 more doctor answer
Seizures mouth ulcers hepatocellular disease low blood count anticardiolipin antibodies 1:80 speckled ANA osteoarthritis spine Si joints LUPUS maybe?
Might methotrexate help w/dysautonomia symptoms caused by autoimmune disorder like lupus when standard tx (floninef & salt)don't' work but prednisone does?
May not be best: Dysautonomia due to lupus could be due to neurological involvement such as autonomic neuropathy, or due to adrenal suppression as a consequence of prolonged steroid treatment. In the first case Methotrexate might not be a strong enough immunosuppressor; its role in lupus is mainly limited to treating arthritis. In the second case, the treatment would be supplemental steroids such as florinef (fludrocortisone). ...Read moreSee 2 more doctor answers
Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.
Maybe: ANA positive diseases are related. Diagnosis is based not just on serologic testing, but also on your clinical symptoms. You should be evaluated by a rheumatologist in order to receive an accurate diagnosis and then receive the most appropriate treatment. ...Read moreSee 1 more doctor answer
Does plaquenil (hydroxychloroquine) prevent/slow down organs from being attacked, or just mask lupus symptoms?
Plaquenil (hydroxychloroquine): or hydroxychloroquine is actually an antimalarial medication but it is useful in treating inflammation such as found in lupus. It works by shutting off part of the immune system, so it's not really masking the symptoms- it's stopping the disease process in your case. Be sure to have regular check ups while on this medicine, esp eye examinations. That's one of the dangerous side effects 2 look out4 ...Read more
Developed anca positive vasculitis with antihistone ab 1.4 and ESR 80. Can Losartan inhibit angiogenesis and make vasculitis or inflammation worse?
Rheumatology: Studies show that losartan can be associated with a drug induced ANCA positive Henoch-Schonlein purpura which is a form of vasculitis. Antinuclear antibody test looking to rule out not rule in drug induced systemic lupus erethematosus may have been performed. If you had another ANCA associated vasculitis and you are on losartan rheumatologist will instruct you if you should be taking it, call them ...Read moreSee 1 more doctor answer
I have mild SLE (no organ involvement), only on Plaquenil (hydroxychloroquine). No antiphospholipid antibodies, high BP or f. history of blood clots. Is birth control safe?
Probably safe: Per Uptodate Oral contraceptives containing low levels of estrogen are probably safe in patients with mild well-controlled SLE. Avoid use in pts with with increased risks of clotting. Patients with anti phospholipid antibodies, nephrotic syndrome, hx of thrombophlebitis, CAD, migraines, smokers. uncontrolled HTN. Of course weigh the risks and benefits with your personal Doctor. ...Read more
Could an immunoglobulin deficiency effectively mask an autoimmune disorder from auto-antibody screens such as AMA ANA etc.or is it a separate thing ?
No: When there is a total deficiency of the immunoglobulin, there can be no autoantibody formed from that particular class of immunoglobulin. Thus it is not a masking. However this does not rule out that other immune mechanisms may not be the cause for a certain illness. ...Read moreSee 1 more doctor answer
+ana, postive 320 and anti ribosomal p antibodies. All other labwork is normal. Symptoms are photosenstivity, livedo reticularis, mouth sores.....?
See allergist and dermatologist: Your symptoms and clinical picture suggests to different diagnosis as -either simple allergic condition ,or connective tissue disease,lupus erythrommatosus .You should be further investigated as blood test and may be skin biopsy may give clue to diagnosis .Avoid sun exposure ,taking anti allergic medication and steroids may help .Consult the dermatologist ...Read moreSee 9 more doctor answers
Selectively separating plasma from undesirable components such as autoimmune antibodies is called what?
Plasmaphoresis: PlasmaphoresisGet a more detailed answer ›
1 small red purpura on leg no itch. Lab = drug reaction. Doc says senile purpura. Now rust color, Same dx? Daily aspirin. Platelets MVP CBC normal.
Not a disease: An isolated purpuric patch in someone taking aspirin is not a cause for concern. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more
I have a positive ana, positive lupus anticoagulant, 386 value for microsomal antibodies. C3 of 113, C4 of 53. A rash on face could it be lupus?
Yes: If the rash fits the butterfly or discoid rash or the subacute lupus skin lesion. ANA titer is usually high in lupus; you have not listed yours. The c3 and c4 are markers of disease activity and famously nonspecific. Don't try to self-diagnose; your age of 54 is a bit high for new-onset lupus though it's not impossible. ...Read moreSee 1 more doctor answer
Whether New oral anticoagulant drugs (pradaxa 150 2x/day) may be combined with anti-platelet drugs (Plavix (clopidogrel) 75 mg/day)?? i'm in Af also CAD??
Yes: be carful about bleeding because there is no antidote for these new agents. ...Read more
Abnormal hemostasis lab results but negative for von willenbrand disease. Pfa-100 ordered. What other platelet disorders are being considered? 31f
Abn platelet fnctn: Hereditary platelet function disorders disorders of platelet adhesion disorders of platelet aggregation disorders of platelet secretion disorders of platelet procoagulant activity combined abnormalities of number and function acquired platelet function disorders( by Aspirin etc). ...Read more
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