Top
40
Doctor insights on: Lupus Anticoagulant Symptoms

Share
1

1
Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?

Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?

POSSIBLE: Your lab outcomes plus the prior DVT, seem consistent, but other labs may further assist such as changes in PTT. Might get additional opinion to confirm your diagnosis, and exclude other problems, but certainly antiphospholipid antibody syndrome seems high on list. ...Read more

Dr. Boris Aronzon
533 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


2

2
Do people with lupus have the lupus anticoagulant?

Do people with lupus have the lupus anticoagulant?

Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read more

See 1 more doctor answer
3

3
Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.

Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.

Maybe: ANA positive diseases are related. Diagnosis is based not just on serologic testing, but also on your clinical symptoms. You should be evaluated by a rheumatologist in order to receive an accurate diagnosis and then receive the most appropriate treatment. ...Read more

See 1 more doctor answer
4

4
Need information on circulatory lupus anticoagulant?

Need information on circulatory lupus anticoagulant?

See below: It is an immunoglobulin that binds to protein and phospholipids of the cell membrane.In fact it can be prothrombotic unless treated with an anticoagulant such as coumadin! ...Read more

7

7
Symptoms of lupus crisis?

It depends: The symptoms of a lupus flare depend on the exact organ systems involved and the extent of the involvement. ...Read more

8

8
How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

9

9
1280 ANA, -ENA and compliments. lupus symptoms, but rheum said no lupus because I have Blau Syndrome, rare autoinflammatory, doesn't cause ANA. Help!

1280 ANA, -ENA and compliments. lupus symptoms, but rheum said no lupus because I have Blau Syndrome, rare autoinflammatory, doesn't cause ANA. Help!

Talk to your MD: Blau syndrome, systemic granulomatous syndrome, is a rare autoimmune disease affecting many organs. It can simulate, at least initially, other autoimmune diseases. There is effective treatment for most patients with the disease. Either talk with your rheumatologist or go to a tertiary medical center. ...Read more

10

10
Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

13

13
What are lupus symptoms?

See details: There are 11 diagnostic criteria for lupus. Google them. ...Read more

14

14
Is it sle or lupus anticoagulant that causes pregnancy problems?

Is it sle or lupus anticoagulant that causes pregnancy problems?

Lupus and pregnanacy: Sle or lupus is less likely to cause serious problems in pregnanacy if the disease is well controlled before conception, especially if you are cared for by both a rheumatologist and "high risk" ob. Also presence of lupus anticoagulant can be managed suceesfully. ...Read more

See 1 more doctor answer
16

16
Can you explain the diagnosisof purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome?

No: This is a question that can be adequately answered only by complicated drawings, references to appropriate testing of several clotting factors, and analysis by a rheumatologist and a hematologist. In my patients such a discussion would take at least an hour. Hire a hematology consultant. ...Read more

18

18
Autoimmune symptoms (fatigue, joint/muscle pain, headaches, gastro issues, etc.)Tested for lupus. RNP was 2.5. No lupus. Rheum said restest. Thoughts?

Autoimmune symptoms (fatigue, joint/muscle pain, headaches, gastro issues, etc.)Tested for lupus. RNP was 2.5. No lupus. Rheum said restest. Thoughts?

These are not: specific to autoimmune disease. Lupus would have specific and fairly severe and quite noticeable symptoms. http://www.lupus.org/answers/entry/what-is-lupus ...Read more

20

20
What are the symptoms of systemic lupus erythematosus?

What are the symptoms of systemic lupus erythematosus?

Many: People with lupus may have joint pain, skin rashes, chest pain, heart probelms, hair loss, fingers changing color in the cold, rash in the sunshine, neuro-psychologic problems. These are only soemof the symtpoms peopel can have. They can also have none of these. Your physician will evaluate all of these, get labs tests and imaging. ...Read more

See 1 more doctor answer
22

22
What is the lupus anticoagulant?

Clotting antibody: The lupus anticoagulant is a phospholipid antibody that can bind to cell membranes to make them sticky and increase the risk of blood clotting. It can occur transiently as the result of infections or medicines, or it can occur as spontaneous auto-antibodies or with autoimmune diseases. It may increase the risk of infertility or recurrent miscarriages. ...Read more

23

23
How does someone get lupus anticoagulant?

Part of lupus : You produce antibodies that can interact with the process of blood clotting to cause the blood to clot more easily than normal. This is part of the immunologic abnormalities associated with lupus in some affected individuals. ...Read more

24

24
How many lupus anticoagulant tests are there?

How many lupus anticoagulant tests are there?

many: There are tests for 3 forms of anticardiolipin antibodies, 3 forms of antiphospholipid antibodies, russell viper coagulation test and tests for specific components of coagulation and general tests (e.g., prothrombin time). ...Read more

25

25
Do people with lupus have the lupus anticoagulant?

Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read more

See 1 more doctor answer
26

26
What medicine do I take for the lupus anticoagulant?

None.: Lac is a laboratory finding of uncertain clinical significance. It predisposes to the development of autoimmune diseases such as lupus erythematosus, vitiligo, pernicious anemia, thyroiditis, inflammatory bowel disease, type i diabetes mellitus and addison's disease. If your rheumatologist has diagnosed you with a particular disorder, medications may be warranted on a clinical basis - not for lac. ...Read more

28

28
What is the definition or description of: lupus anticoagulant?

Poorly Named Test: If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune disease should have done. ...Read more

See 1 more doctor answer
31

31
Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

32

32
I was recently tested for lupus anticoagulant and it was postitive. Does that mean I have lupus?

No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for. ...Read more

See 1 more doctor answer
33

33
I have lupus anticoagulant and dr. Is wanting to put me on xorelto! i've read mixed reviews mostly against, & cost is a factor? What is your opinion?

I have lupus anticoagulant and dr. Is wanting to put me on xorelto! i've read mixed reviews mostly against, & cost is a factor? What is your opinion?

Use caution: Xarelto is awesome if you listen to the manufacturer. Unlike coumadin, (warfarin) you do not require regular blood draws to evaluate effect. However, there is also no clear reversal agent if one does sustain a bleed. It can be a terrible situation when someone has a brain hemorrhage, etc, from relatively trivial fall. ...Read more

35

35
Need information on circulatory lupus anticoagulant?

See below: It is an immunoglobulin that binds to protein and phospholipids of the cell membrane.In fact it can be prothrombotic unless treated with an anticoagulant such as coumadin! ...Read more

36

36
Can i get disability for lupus anticoagulant disorder.

Can i get disability for  lupus anticoagulant disorder.

Impossible to say: It depends on many factors, not just on a diagnosis. If you are able to work, you are not disabled no matter what the underlying medical issues. ...Read more

37

37
What are dangers of conceiving if one has lupus anticoagulant and pcos?

Danger small but ...: Pcos makes becoming pregnant difficult without treatment; pregnancy is usually ok though excess weight raises risk mildly; lupus anticoagulant requires careful study and may raise the risk of late miscarriage and require special treatment throughout pregnancy. ...Read more

39

39
How risky is it to get pregnant with lupus anticoagulant?

No big deal usually.: Depending on whether you have a diagnosis of lupus or prior clotting problems, this may or may not be significant for your pregnancy. Studies show that most women with lac have normal pregnancies. Lupus anticoagulant (lac) is a laboratory finding and in and of itself not significant for predicting clinical outcomes. If you have systemic lupus erythematosus the plot thickens and you need to see mfm. ...Read more

40

40
Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Lupus Anticoagulant (Definition)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more