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Doctor insights on: Lupus Anticoagulant Miscarriage

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Can lupus anticoagulant be detected before a miscarriage occurs? Can you get rid of the anticoagulant?

Can lupus anticoagulant be detected before a miscarriage occurs?  Can you get rid of the anticoagulant?

Yes. Maybe.: Lupus anticoagulant can be diagnosed by a blood test, and in women with recurrent miscarriages, it can be treated with Heparin and aspirin. But not everyone with lupus anticoagulant has recurrent miscarriages. Some people may have natural protective factors. And most people with one miscarriage will have a normal work-up & normal next pregnancy. So we usually test for it after 2 miscarriages. ...Read more

Dr. Boris Aronzon
504 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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I miscarried twice. Doc advised me to do thrombophilia screen, anticardiopin antibody and lupus anticoagulant - what are they?

I miscarried twice. Doc advised me to do thrombophilia screen, anticardiopin antibody and lupus anticoagulant - what are they?

Tests for clotting: These are tests for abnormal clotting factors that, if present, may be causing you to miscarry. Someone of these causes can be treated during pregnancy. ...Read more

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I have been having recurrent miscarriages.I tested weakly positive for lupus anticoagulant. Can I have a successful pregnancy on baby aspirin?

I have been having recurrent miscarriages.I tested weakly positive for lupus anticoagulant. Can I have a successful pregnancy on baby aspirin?

No: Low dose Aspirin is not an effective therapy for this issue. You need to be on subcutaneous heparin. See a rheumatologist or hematologist for appropriate treatment. ...Read more

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I have had two miscarriages pcos thin. I tested positive for mthr-gene and lupus anticoagulant. Should i look at IUI next time? I get period 18 days

I have had two miscarriages pcos thin. I tested positive for mthr-gene and lupus anticoagulant. Should i look at IUI next time? I get period 18 days

Before pregnancy!: Make sure that both you ; your hubby (if + for the mthfr 677 or 1298 genotypes), are first being treated with l-methylfolate, p5p, and methylcobalamin (at the minimum), to give any pregnancy a best chance for success. Also, do not take a prenatal vitamin that has regular fa if you are a known mthfr+ person. The regular Folic Acid blocks the receptors that need to let l-mthf through. Pm me! ...Read more

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Chance of conceiving if one has lupus anticoagulant?

Issue is safety: Issue is safety. Conception should not be an issue as long as the anticoagulant effect controlled and warfarin/coumadin not used. ...Read more

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Have lupus anticoagulant, how soon can I become pregnant?

No concern: Lac may increase the risk of some complications in pregnancy, but has no impact on when you should get pregnant. It may be, however, that there was a condition that led your doctor to test for lac, that has some impact on this question. Check with your doctor. ...Read more

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How common is an elevated lupus anticoagulant level in a 4 year old girl?

How common is an elevated lupus anticoagulant level in a 4 year old girl?

Not common, but can.: It can occur. However, it would be much rarer for your four year old to have sle. Antiphospholipid syndrome can occur by itself, or with other conditions. ...Read more

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What to expect with a diagnosis of purpura fulmicans and lupus anticoagulant?

What to expect with a diagnosis of purpura fulmicans and lupus anticoagulant?

Catastrophic APS Syn: You must get the full panel exam for an antiphospholipid syndrome like labs and good history and physical. Aps can lead to arterial and venous thrombosis, frequent miscarriages and may need Coumadin (warfarin) - blood thinner. ...Read more

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Can blood work result in a false positive result for lupus anticoagulant factor?

No: Positive is positive. However, it is the degree of positivity that is clinically important. Low positive values are generally not clinically important. ...Read more

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Lupus Anticoagulant (Definition)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more