Doctor insights on:
Lupus Anticoagulant And Factor V Leiden
My mum has lupus I have been tested and tould I have factor v Leiden can someone please explain what it is and how it will affect me in my life?
Depends: The risk of blood clot development depends on weather you have one or two copies of the gene for Factor V deficiency, A person with 2 copies of the gene have increase in risk of DVT, pregnancy loss and pregnancy complications. Your physician can give you more information based on your test results.See 1 more doctor answer
Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more
I have factor v and lupus anticoagulant syndrome....For the past year my face has darkening spots on my cheeks. Fingers hurt. My hair is thinning bad?
APL vs Medication: There are many options. This could be related to an associated lupus like syndrome in your settings or it could be due to your medications or both. Your evaluation will be able to clarify these issues.
Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes.?
Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves.
No: Positive is positive. However, it is the degree of positivity that is clinically important. Low positive values are generally not clinically important.
Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.
I have lupus anticoagulant and dr. Is wanting to put me on xorelto! I've read mixed reviews mostly against, & cost is a factor? What is your opinion?
Use caution: Xarelto is awesome if you listen to the manufacturer. Unlike coumadin, (warfarin) you do not require regular blood draws to evaluate effect. However, there is also no clear reversal agent if one does sustain a bleed. It can be a terrible situation when someone has a brain hemorrhage, etc, from relatively trivial fall.
Is he homozygous?: If your father is homozygous for factor v leiden, then you are at least a carrier or heterozygous. Even heterozygous people have about five fold greater risk of thrombosis. If he is heterozygous then you have a 50% chance of being heterozygous.
Depends: If your father is homozygous for the mutation, you are heterozygous for factor v leiden. If your father is heterozygous for the mutation you have a 50% chance of being heterozygous. This is assuming that your mother does not have the mutation. Even heterozygotes/carriers have about 5 fold greater risk of thrombosis. T.
Dr Hoepfner, I was diagnosed with an enlarged spleen at 13.4 cm is that something to be alarmed about? I am a Factor V Leiden def. Patient who takes
That measurement: Is borderline and could be normal in a particular patient.
My sis tested (+) factor V Leiden and her Dr suggested I get tested. I was fixing to start Clomid (clomiphene) 4 secondary hypergonadism. R SERMS contraindicated?
FH Leiden factor: Estrogens increase the risk of clotting. Clomid (clomiphene) is a non steroidal selective estrogen receptor modulator. It is not an estrogen. It has not been associated with significant increase in clotting to date, so should be OK. With FH of Leiden positive (I assume means deficient in Leiden V) which increases the risk of clots, get tested and let your doctor know of the results prior to starting.
I have factor v leiden was wondering what contraception methods could people with this condition use?
Not oral: Contraceptive pill. You may use any of the barrier methods and iud. If you are done with childbearing, tubal ligation would be an option. It would be prudent to discuss the matter with your doctor.
No: Both are very common and this is probably a coincidence. The factor v gene isn't part of the pathway by which new vessels form, and this speaks against there being any correlation. There are a few other genetic syndromes with distinctive hemangiomas, but factor v has not been linked to any.
A good choice: The Skyla IUD is a good choice for patients with inherited thrombophilias such as Factor V and MTFHR. It is a safe choice as it does not contain Estrogen.
Lovenox (enoxaparin): The woman needs to be on long term Heparin treatment. Usually a subcutaneously injected preparation is used.
I have factor V Leiden. No longer have insurance can I take asprin 2x a day to help thin my blood?
YES: However, I do suggest a formal; hematology consultation and evaluation.
Can I take advil if I have a heterozygote mutation of factor V leiden? Any extra increase risk of clot? Thank you
No extra risk: Advil will not increase your risk for clots. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex.
I can't seat for extended periods of time w/out my lft leg hurting really bad when I try to get up&move. Could this be the factor v Leiden disorder?
Not likely: What you describe is more concerning for some compromise of the nerve (s) of the spine. Alternatively, it could just be increased muscle tone/spasm related to prolonged sitting. Factor V leiden predisposes people to blood clots and blood clots, if going to cause pain, usually cause pain whether seated or standing.
I have factor v leiden deficiency and take 20mg warfarin daily. Can I take ace? (it's a appetite suppressant)
I would not: Recommend as dietary changes can significantly alter warfarin metabolism.
I have factor v leiden, I'm having horrible cramping during my periods. Could this be caused from factor v, if so what should I do?
No association: Factor 5 Leiden is a disorder that increases your risk of clotting. Although I understand why you might think that this might affect your period, it is unlikely that they are associated. However you can lighting or eliminate your period by getting on a birth control method such as an IUD or using a combined hormonal methods. Please consult a gynecologist for more details.
Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more
If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more