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Doctor insights on: Lupus Anticoagulant And Factor V Leiden

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My mum has lupus i have been tested and tould i have factor v Leiden can someone please explain what it is and how it will affect me in my life?

My mum has lupus i have been tested and tould i have factor v Leiden can someone please explain what it is and how it will affect me in my life?

Depends: The risk of blood clot development depends on weather you have one or two copies of the gene for Factor V deficiency, A person with 2 copies of the gene have increase in risk of DVT, pregnancy loss and pregnancy complications. Your physician can give you more information based on your test results. ...Read more

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Dr. Boris Aronzon
503 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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I have factor v and lupus anticoagulant syndrome....For the past year my face has darkening spots on my cheeks..Fingers hurt..My hair is thinning bad?

I have factor v and lupus anticoagulant syndrome....For the past year my face has darkening spots on my cheeks..Fingers hurt..My hair is thinning bad?

APL vs Medication : There are many options. This could be related to an associated lupus like syndrome in your settings or it could be due to your medications or both. Your evaluation will be able to clarify these issues. ...Read more

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Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?

Are  any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?

Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more

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Can blood work result in a false positive result for lupus anticoagulant factor?

Can blood work result in a false positive result for lupus anticoagulant factor?

No: Positive is positive. However, it is the degree of positivity that is clinically important. Low positive values are generally not clinically important. ...Read more

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Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Normally: a factor V deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time. ...Read more

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I have lupus anticoagulant and dr. Is wanting to put me on xorelto! i've read mixed reviews mostly against, & cost is a factor? What is your opinion?

I have lupus anticoagulant and dr. Is wanting to put me on xorelto! i've read mixed reviews mostly against, & cost is a factor? What is your opinion?

Use caution: Xarelto is awesome if you listen to the manufacturer. Unlike coumadin, (warfarin) you do not require regular blood draws to evaluate effect. However, there is also no clear reversal agent if one does sustain a bleed. It can be a terrible situation when someone has a brain hemorrhage, etc, from relatively trivial fall. ...Read more

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My father has factor v leiden, does that mean i also have it?

Is he homozygous?: If your father is homozygous for factor v leiden, then you are at least a carrier or heterozygous. Even heterozygous people have about five fold greater risk of thrombosis. If he is heterozygous then you have a 50% chance of being heterozygous. ...Read more

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If my father has factor v leiden, does that mean i also have it?

If my father has factor v leiden, does that mean i also have it?

Depends: If your father is homozygous for the mutation, you are heterozygous for factor v leiden. If your father is heterozygous for the mutation you have a 50% chance of being heterozygous. This is assuming that your mother does not have the mutation. Even heterozygotes/carriers have about 5 fold greater risk of thrombosis. T. ...Read more

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My sis tested (+) factor V Leiden and her Dr suggested I get tested. I was fixing to start Clomid (clomiphene) 4 secondary hypergonadism. R SERMS contraindicated?

My sis tested (+) factor V Leiden and her Dr suggested I get  tested. I was fixing to start Clomid (clomiphene) 4 secondary hypergonadism. R SERMS contraindicated?

FH Leiden factor: Estrogens increase the risk of clotting. Clomid (clomiphene) is a non steroidal selective estrogen receptor modulator.It is not an estrogen. It has not been associated with significant increase in clotting to date, so should be OK. With FH of Leiden positive (I assume means deficient in Leiden V) which increases the risk of clots, get tested and let your doctor know of the results prior to starting. ...Read more

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Lupus Anticoagulant (Definition)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more