Doctor insights on:
Lupus Anticoagulant And Factor V Leiden
Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?
Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more
Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more
Risk for blood clots: People homozygous for factor v leiden are about 50 times more at risk of developing blood clots in their veins and complications related to that. See this site for more info. http://www.mayoclinic.org/diseases-conditions/factor-v-leiden/basics/definition/con-20032637. ...Read more
Yes: Factor v leiden is a genetic condition. If you have one copy of a fvl mutation, you are heterozygous with an increased risk of blood clotting. If you have 2 copies you are homozygous with an even higher risk of clotting. The inheritence pattern is simple mendelian genetics. You get one copy of the gene from your mother and one from your father. ...Read moreSee 1 more doctor answer
Thrombosis: People who inherit the leiden variant of coagulation factor v are at incresed risk of venous thrombosis. Those who are heterozygotes their risk is 5-10 fold higher, homozygotes are about 50 fold greater risk. Women on birth contol pills are partiuclarly susceptible to thrombosis if they have leiden factor v. If the affected individual develops thromobsis, life long anti-coagulation may be needed. ...Read more
Is a simple coagulation lab test (PT/PTT INR & Fibrinogen) sufficient to diagnose Protein C,
&/or Factor V leidmen mutation disorders?
Hbg, hct, rbc, plt, mvc, all at top of normal range. Does this ^ clotting risk? Hx: fact v leiden & aps. On lovenox (enoxaparin) 100mg bid
No: These values would not increase the risk. Normal is normal. ...Read more
Tendency to clot: Factor v leiden is a hereditary abnormality of a clotting protein that increases your risk of forming clots, notably in the veins (phlebitis). If you are undergoing a procedure that would also increase this risk (surgery, prolonged immobilization), Lovenox (enoxaparin) might be used preventively. It is only for short-term use, and oral drugs such as warfarin would be used if you need long-term protection. ...Read more
No: Both are very common and this is probably a coincidence. The factor v gene isn't part of the pathway by which new vessels form, and this speaks against there being any correlation. There are a few other genetic syndromes with distinctive hemangiomas, but factor v has not been linked to any. ...Read more
Hemotologist confirmed Enoxaparin causing me to have elevated liver enzymes. 6w pregnant- history of PEs, Factor V, Factor II. Any other options?
Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?
All could be: Depending on the spectrum of abnormalities associated with the syndrome all of these tests results could be abnormal. ...Read more
20y o woman, have thrombophilia factor vii (7) heterozygote gene mutation, I have had 7week miscarriage, is thromb. the cause? I am very healthy
What does high thrombin 14.5, prothrombin 22.7, APTT 79, APTT 1:1 NP 47 mean? SLE patient. Risk of bleed or risk of clots? C3-70,CH50- 22, C4-norm.
I have venous insufficiency and factor v leiden mutation. What can do for debilitating leg/body cramps? (pcp has ruled out the usual causal suspects.)
I found out I have Factor V Deficiency. My mother has Factor V leiden. What is the difference between those?
Huge difference: Factor V deficiency of a clotting factor which can result in a hemophilia like illness with excessive bleeding. On the other hand Factor V Leiden refers to a mutation which increases the risk of clotting and thrombosis. The distinction is very important. Women with Factor V Leiden should not take hormonal contraception. Please clarify your diagnosis with your physician as soon as possible! ...Read more
When testing for Antiphospolipid Antibody Syndrome, does taking baby aspirin affect the Lupus Anticoagulant (PTT-LA, dRVVT) test results?
40yr old Fem Sed Rate Rising (Cont 2) History: Pos ANA, FM, Lupus Anticoagulant, Hypothyroidism, LE Edema. What does all this mean?
See your MD: The positive ANA and lupus anticoag may be associated with potential for blood clotting issues and clearly represent autoimmune disease potentially, of which the hypothyroidism may be a part. You must be seen by an hematologist or immunologist and be evaluated for systemic autoimmune issues. the elevated sed rate is also associated with inflammatory disease. Feel better! ...Read more
Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more
If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more
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