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Doctor insights on: Lupus Anticoagulant

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Lupus Anticoagulant (Overview)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune disease should have done.


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What is the lupus anticoagulant?

What is the lupus anticoagulant?

Clotting antibody: The lupus anticoagulant is a phospholipid antibody that can bind to cell membranes to make them sticky and increase the risk of blood clotting. It can occur transiently as the result of infections or medicines, or it can occur as spontaneous auto-antibodies or with autoimmune diseases. It may increase the risk of infertility or recurrent miscarriages. ...Read more

Lupus Anticoagulant (Overview)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune disease should have done.


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Do people with lupus have the lupus anticoagulant?

Do people with lupus have the lupus anticoagulant?

Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read more

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Living with Lupus (Checklist)

Schedule regular clinic visits with rheumatologist & don't miss them
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Take all of your medications every day. Discuss changes with rheum doc.
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Avoid unprotected sun exposure. Wear SPF30+ and a hat everyday.
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Get plenty of rest every day -- fatigue can trigger flares
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Need information on circulatory lupus anticoagulant?

Need information on circulatory lupus anticoagulant?

See below: It is an immunoglobulin that binds to protein and phospholipids of the cell membrane.In fact it can be prothrombotic unless treated with an anticoagulant such as coumadin! ...Read more

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I have factor v and lupus anticoagulant syndrome....For the past year my face has darkening spots on my cheeks..Fingers hurt..My hair is thinning bad?

I have factor v and lupus anticoagulant syndrome....For the past year my face has darkening spots on my cheeks..Fingers hurt..My hair is thinning bad?

APL vs Medication : There are many options. This could be related to an associated lupus like syndrome in your settings or it could be due to your medications or both. Your evaluation will be able to clarify these issues. ...Read more

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Can blood work result in a false positive result for lupus anticoagulant factor?

No: Positive is positive. However, it is the degree of positivity that is clinically important. Low positive values are generally not clinically important. ...Read more

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I was recently tested for lupus anticoagulant and it was postitive. Does that mean I have lupus?

No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for. ...Read more

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Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more

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Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Normally: a factor V deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time. ...Read more

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Dr. Boris Aronzon
504 doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more