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Doctor insights on: Lupus And Plaquenil

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I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?

I have  recurring flares of  rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back.  My ANA is 6:40.  I'm on plaquenil. Why are all my other antibodies neg for lupus?

Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more

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Dr. Janice Alexander
172 doctors shared insights

Hydroxychloroquine Sulfate (Definition)

Hydroxychloroquine sulfate is an addiction reducing agent which is a ...Read more


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I have lupus. On Plaquenil.Eat very health & exercise daily.My current labs & cholesterol look great & normal. Is it possible I no longer have lupus?

I have lupus. On Plaquenil.Eat very health & exercise daily.My current labs & cholesterol look great & normal. Is it possible I no longer have lupus?

Unlikely: It's quite unlikely that you are now lupus free. I am not aware of any cases where patients have been able to resolve their lupus unless it started due to medications. You could have your lupus bloodwork repeated however I am not sure if that would be accurate. ...Read more

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I have lupus and take plaquenil (hydroxychloroquine). I've been taking biotin for a while to see if it would help hair loss. Is there anything I can do?

I have lupus and take plaquenil (hydroxychloroquine). I've been taking biotin for a while to see if it would help hair loss. Is there anything I can do?

Hard choice: If it controls your lupus that makes it a difficult choice. Lupus itself can cause hair loss, but on the other hand if placqunil works it is an excellent choice. You and your doctor need to discuss how bad it is, what other choice is available.because other than stopping it there is no other treatment for hair loss due to placquenil. Some reports say the hair loss stops and reverses but no studies ...Read more

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I'm treated 4 lupus like disease. Plaquenil (hydroxychloroquine) controlled flares.But dizziness required constant prednisone.Can methotrexate help with my dizzy spells?

I'm treated 4 lupus like disease. Plaquenil (hydroxychloroquine) controlled flares.But dizziness required constant prednisone.Can methotrexate help with my dizzy spells?

Steroid-sparing: We call Methotrexate a steroid-sparing drug because it can often take the place of Prednisone in the long term. I do agree with the other md who mentioned you need a more specific diagnosis as well. ...Read more

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I am unsure that my dr is correct of mylupus diagnosis (no labs + other than ANA) 2nd opinion dr says no lupus if I take plaquenil (hydroxychloroquine) w/o disease will hurt me?

No plaquenil (hydroxychloroquine): Plaquenil (hydroxychloroquine) is not an innocuous drug and needs careful follow-up. A positive ANA is present in many apparently healthy people and a diagnosis of lupus must not be made lightly based on this test alone. Follow the 2nd opinion and consider finding another family doctor. ...Read more

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How dose such a small maintenance dose of prednisone 5 mg daily w/ plaquenil (hydroxychloroquine) prevent my lupus flares more than plaquenil (hydroxychloroquine) alone? It works great.

How dose such a small maintenance dose of prednisone 5 mg daily w/ plaquenil (hydroxychloroquine) prevent my lupus flares more than plaquenil (hydroxychloroquine) alone?  It works great.

Can help!: While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. There are a number of reasons you might feel so much better on a low (5mg) dose: 1.Plaquenyl has not fully kicked in. 2. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. 3. You will get a modest energy boost at 5mg! ...Read more

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I have postural orthostatic tachycardia syndrome from lupus. I only take plaquenil (hydroxychloroquine) since lupus gave me pots is that a poorer prognosis since its the nervous system (i heard if it affects CNS its bad)?

I have postural orthostatic tachycardia syndrome from lupus. I only take plaquenil (hydroxychloroquine) since lupus gave me pots is that a poorer prognosis since its the nervous system (i heard if it affects CNS its bad)?

YES and many more : Few listed: cardiomyopathy (rare, relationship to Hydroxychloroquine unclear) central nervous system: ataxia, dizziness, emotional changes, headache, irritability, lassitude, nervousness, nightmares, psychosis, seizure, vertigo dermatologic: alopecia, angioedema, bleaching of hair, pigmentation changes (skin and mucosal; black-blue color), rash (acute generalized exanthematous pustulosis, etc. ...Read more

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Dr. Sheila Smith
214 doctors shared insights

Plaquenil (Definition)

Plaquenil is an addiction reducing agent which is a ...Read more