Doctor insights on:
Lupus And Endometrial Hyperplasia
Overgrown lining: The lining of the uterus is called the endometrium. When it is too thick and/or overgrown, it is called hyperplasia. Frequently this is just a benign thickening but it can be atypical (abnormal) or even cancerous. Thickened lining in older women is more worrisome and should be biopsied. It is a diagnosis made by ultrasound, so it is typically found when evaluating abnormal bleeding.See 1 more doctor answer
Depends on patient: A woman will have a higher risk of endometrial hyperplasia if they have prolonged exposure to unopposed estrogen. Women with higher risk include those suffering from anovulation (no menstrual cycle), hirsutism (abnormal nhair growth), polycystic ovarian disease, obesity, estrogen replacement therapy after menopause.
Cancer or not: Neoplasia of the uterine lining is an early cancer. Hyperplasia refers to exuberant growth, which can be a cancer precursor.
It's a indicator: Endometrial hyperplasia (overgrowth of the uterus lining) means that the uterus is being exposed to continuous estrogen, which is a risk factor for endometrial cancer. So it indicates that conditions are favorable for the development of cancer, and it can also allow an early cancer to hide more easily. Atypical hyperplasia means overgrowth of abnormal cells and an even higher risk of cancer.See 1 more doctor answer
Not really curable: You'll be taught how to manage it. In addition to meds and eating sensibly, consider getting back into the aerobic sports activities that you enjoy most, much more intensely.
Hyperplasia: Technically endometrial hyperplasia can only be diagnosed by an endometrial biopsy. An ultrasound can reveal a thickened endometrium which may aid in the decision process to have a biopsy. Endometrial hyperplasia itself is not malignant but left untreated it could potentially develop into endometrial cancer. Speak with your doctor and see if you need a biopsy.
Endometrial dx: Endometrial hyperplasia is not "sudden, " it is a progressive thickening of the lining of the uterus due to estrogen effect. Early phases are called "simple hyperplasia." this can progress if untreated to "complex hyperplasia" or "atypical hyperplasia" - if left untreated, it can progress to endometrial carcinoma. Treatment is progesterone hormones to counteract the estrogen.
Is it normal to take medroxyprogesterone every day continuously to treat endometrial hyperplasia with atypia?
Endometrial hyperplasia simple not responding to 100mg progesteron day 10 onwards of cycle; 7 days in start bleeding more than ever?
Clarify: This all depends on many things, and your question if very unclear. Are you saying you start the Progesterone on day 10? And you don't indicate what kind of progesterone. And are you 7 days into your period, or the progesterone? And is this the first month you are on it? Really, none of this doesn't mean it isn't working. You should call the physician who prescribed the medication to discuss.
My gynecologist said I have endometrial hyperplasia and I need an iud. She is sending me to an oncologist. Why is this?
Don't panic: Endometrial hyperplasia is the precursor lesion that has the potential to develop into frank uterine cancer. Your gynecologist is sending you to an oncologist not because you have cancer but because oncologists manage patients who are at high risk of progression to cancer or may have concomitant cancer that is not detected yet. An iud will often reverse hyperplasia.See 1 more doctor answer
Missing issue: It seems your question got cut off. As to hyperplasia it depends on whether it is simple or complex and if there is atypia (weird cells). What type dictates the next step in treatment options.
D&C vs hysterectomy: Endometrial hyperplasia can cause bleeding, and possibly lead to cancer. One effective treatment is hysterectomy, which also allows for thorough pathology examination to be sure there is no cancer already present. Other treatments to avoid hysterectomy include a thorough D&C to remove the abnormal endometrial lining, and possibly hormonal treatments. Your gyn can discuss what is optimal for you.
Yes: Simple endometrial hyperplasia without atypia should respond to cyclic progesterone.
Perhaps: Need more information. Do you have any atypia? How old are you? How much do you bleed? Is a repeat sampling planned? Best Wishes
```EM thickness: US is one way to look at the interior of the uterus, the endometrial lining. If it appears thickened, it can be due to both physiologic or pathologic growth. In patients over 40, pre-neoplastic or neoplastic hyperplasia becomes more likely, but other things may also be present like polyps. Usually a biopsy or curettage would be needed to sort this out.
D&C: Dilation and curettage is one option, in which the lining is gently removed to fully evaluate for higher grade abnormalities concerning for cancer. If there are also atypical cells present, many would recommend a hysterectomy due to the high risk of underlying cancer, or of the abnormality progressing to cancer.See 1 more doctor answer
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