Doctor insights on:
Lupus And Cymbalta
Cymbalta (duloxetine) is an "antidepressant" medication. However, it is an approved treatment for a variety of indications to include (unipolar) depression, anxiety, and chronic pain (related to diabetic neuropathy, musculoskeletal and/or fibromyalgia). Pharmacologically, it primarily enhances 2 different neurotransmitters (serotonin and norepinephrine). It can cause a ...Read more
Hi, i'm concerned about my wife who has lupus and crohns. Despite years of immuno suppressant therapy and steroids she has more days of pain and fatig?
Teasing out the pain: Sometimes the sx are not from the sle or ibd. Fibromyalgia (fms) afflicts 20% of lupus patients. This is a non-inflamatory pain syndrome. Primary symptoms of fibromyalgia are pain and fatigue. Fms is not treated with steroids or immunosuppressant medication. Fms requires a multidisciplinary approach and is not easy to treat. Fms is treated with certain meds (lyrica, cymbalta, savella) and exercise. ...Read more
I'm having terrible chronic pain in my back right knee and ankle and also I guess it's my tail bone it burns and hurts. I also have lupus and fibromya?
Somewhat hereditary?: Sle (lupus) is an auto-immune disorder in which a person's immune system is reacting strongly against parts of his own body. The inflammation from the immune system reaction leads to symptoms. It is believed to be partly genetic or familial (some people may be genetically more likely to get sle) and partly environmental (something happens in a person's life that sets off the auto-immune reaction). ...Read moreSee 1 more doctor answer
Many Sx:: Lupus is both a clinical and laboratory diagnosis. I have many people with some labs indicating sle, but virtually no symptoms or findings suggestive of actual disease. V the attached figure has the cardinal potential problems clinically associated with active lupus. Even if a patient of mine has serologic lupus with no disease, a place them on generic plaquenyl at the appropriate dose. ...Read moreSee 1 more doctor answer
Many possible signs: Lupus has many possible symptoms, depending on what part of the body is affected, and on how severe the condition is. Some symptoms are: fatigue, fever, weight changes, joint pain or stiffness, swollen joints, rash on the cheeks and bridge of the nose, skin rash from sunshine, sores in the mouth, hair loss, poor circulation in fingers or toes from stress or cold temperatures, etc... ...Read moreSee 1 more doctor answer
Estimate: Numbers are difficult to obtain but the estimate for the United States is between 500, 000 and 1.5 million have lupus. Women greatly outnumber men with this disease. Black skinned individuals have the highest incidence. The peak ages are between 15 and 40. ...Read more
Lupus erythematosus is a name given to a collection of autoimmune diseases, in which the human immune system becomes hyperactive and attacks normal, healthy tissues.Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood ...Read more
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