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Doctor insights on: Lupus And Cellcept

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I have sle and bn diagnosed with colitis. Start mesalamine ,have to stop my cellcept. Will my lupus flare? What would happen if I don't take mesalamin

I have sle and bn diagnosed with colitis.
Start mesalamine ,have to stop my cellcept. Will my lupus flare? What would happen if I don't take mesalamin

Why: Why do you have to stop the Cellcept? Mesalamine is an anti-inflammatory so if you stop it there is a chance that colitis symptoms could get worse. However, it doesn't mean that you would automatically get worse if you stop it. Cellcept modulates the immune system and yes the risk of a flare up is higher with SLE especially if you've been well-controlled on it in the past. Chat with your GP. ...Read more

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Sle pt w/ flare in july. Hosp. Had dark brown urine but dr said kidneys ok. Recently GFR is 43. Could this be from plaquenil/cellcept/pred or lupus?

Sle pt w/ flare in july. Hosp. Had dark brown urine but dr said kidneys ok. Recently GFR is 43. Could this be from plaquenil/cellcept/pred or lupus?

See Nephrologist: Early detection and treatment of sle kidney is very important to prevent damage to the kidneys. Creatinine may be normal at certain stages/ types of kidney disease in sle. It is best to be evaluated by a nephrologist. ...Read more

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Sle pt on cellcept (mycophenolate mofetil). If cellcept (mycophenolate mofetil) can cause increased bun why is it used for lupus nephritis? Also can it increase creatinine?

Sle pt on cellcept (mycophenolate mofetil).  If cellcept (mycophenolate mofetil) can cause increased bun why is it used for lupus nephritis? Also can it increase creatinine?

Because it works: Cellcept (mycophenolate mofetil) is the preferred drug for lupus nephritis because it is very effective and has much less risk than alternative meds. It does not cause significant elevations of BUN or creatinine. ...Read more

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On 40mg of Prednisone, Cellcept (mycophenolate mofetil) 1000mg for abt 3wks for CNS lupus. Before meds - norm WBC of 6ish. New CBC + Diff WBC 12.75, abs neut11.60. Concern?

On 40mg of Prednisone,  Cellcept (mycophenolate mofetil) 1000mg for abt 3wks for CNS lupus. Before meds - norm WBC of 6ish. New CBC + Diff  WBC 12.75, abs neut11.60. Concern?

Probably not: The increases in WBC and neut are expected when on high doses of prednisone. However you need to have follow up with your rheumatologist to address this issue since only a direct exam can help detect the presence of an infection which may be masked by the medications you are taking. ...Read more

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I have SLE Lupus and pulmonary fibrosis. Is there a way to get rid of the cough. I use oxygen, take prednisone, cellcept, (mycophenolate mofetil) antimalarial meds.

I have SLE Lupus and pulmonary fibrosis. Is there a way to get rid of the cough. I use oxygen, take prednisone, cellcept, (mycophenolate mofetil) antimalarial meds.

Could not help much: I am sorry to tell unfortunately ,with the SLE and pulm. fibrosis bec. of the lung scarring you have this cough which couldn't be helped much . Supressing cough with medicines like codeine linctus help in heart failure patients ,but in ur case ,should not precipitate infections by suppressing cough. If you are on medicatio like lisinopril for HTN/kidney dz from lupus , it can also contribute ...Read more

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Who all gets lupus?

Who all gets lupus?

Genes, environment: This answer will change as we know more about lupus. We believe that for a person to get lupus, from the limited genetic information we have now, about 10% is from known genetic causes and remaining 90% unknown genetic causes and environmental causes. Environmental causes are largely undefined but important. Think about this: only 30% of identical twins develop lupus together. ...Read more

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Is Lupus reversible?

Is Lupus reversible?

No: Lupus in all its various presentations is treatable but it is not curable nor reversible. In some cases, lupus may go into remission but if it does go into remission, it does so on its own and does not go into remission as a result of treatment. ...Read more

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Is lupus hereditary? 

Somewhat hereditary?: Sle (lupus) is an auto-immune disorder in which a person's immune system is reacting strongly against parts of his own body. The inflammation from the immune system reaction leads to symptoms. It is believed to be partly genetic or familial (some people may be genetically more likely to get sle) and partly environmental (something happens in a person's life that sets off the auto-immune reaction). ...Read more

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What is systemic lupus?

What is systemic lupus?

Autoimmune disease: Lupus erythematosus is a chronic inflammatory disease of unknown cause. The immune system attacks the patient's own body (autoimmunity) and can inflame the skin, joints, kidneys, nervous system, lungs, mucous membranes, and other internal organs. A red rash is often but not always present. Thus, it was named lupus erythematosus meaning "red wolf.". ...Read more

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What are lupus symptoms?

See details: There are 11 diagnostic criteria for lupus. Google them. ...Read more

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How is lupus diagnosed?

Multiple factors: The diagnosis of lupus is made based on a constellation of clinical and laboratory criteria. That is there are a number of pre-determined symptoms, physical signs (things a Dr. sees when examining you), and findings on bloodwork. A minimum number of these must be present in order for the diagnosis to be made. So, you would need to have a physical exam and have blood work drawn. ...Read more

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What are tests for lupus?

See details.: Start with an ana. If that is positive check for dna, ena, ssa and ssb antibodies. If the ANA is negative, i strongly suggest that no other tests be done. ...Read more

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What is the cause of lupus?

What is the cause of lupus?

Genes, environment: This answer will change as we know more about lupus. We believe that for a person to get lupus, from the limited genetic information we have now, about 10% is from known genetic causes and remaining 90% unknown genetic causes and environmental causes. Environmental causes are largely undefined but important. Think about this: only 30% of identical twins develop lupus together. ...Read more

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What are symptoms of lupus?

What are symptoms of lupus?

Complex: Lupus is a complex autoimmune disease in which the body is attacking its own tissue. Lupus is famous for affecting different people in different ways. The effects can be so different from person to person that it does not even look like they have the same diagnosis. The diagnosis is best made by a rheumatologist who sees a lot of lupus patients. ...Read more

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What is lupus and symptoms?

What is lupus and symptoms?

Complex: Lupus is a complex autoimmune disease in which the body is attacking its own tissue. Lupus is famous for affecting different people in different ways. The effects can be so different from person to person that it does not even look like they have the same diagnosis. ...Read more

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How to tell if I have lupus?

How to tell if I have lupus?

See a rheumatologist: I would see a rheumatologist. To have lupus, you have to have symptoms compatible with the diagnosis and lab results to help confirm the diagnosis. ...Read more

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How to know if I have lupus?

See details: You see a rheumatologist. If the history and blood work are compatible with the diagnosis, you have lupus. ...Read more