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Doctor insights on: Lupus Ana Test

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I have been diagnosed with fibromyalgia, but have a lot of lupus symptoms. My ANA test came back as "indeterminate". What does this mean?

I have been diagnosed with fibromyalgia, but have a lot of lupus symptoms. My ANA test came back as "indeterminate". What does this mean?

Better test: Still the better test to determine the difference between lupus and fibromyalgia (fms) is a history and physical exam done by a rheumatologist. Lupus and fms have some similar symptoms but are very different. Lupus - autoimmune disease. Fms - not autoimmune. The ANA is not the deciding factor between the two. The ANA never makes a definite diagnosis. Other blood tests (by rheumatologist) can help. ...Read more

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Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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Can you have symptoms of lupus years before the ANA test positive?

Can you have symptoms of lupus years before the ANA test positive?

No: If the ANA and other autoantibodies are negative, it is very unlikely that you have lupus. ...Read more

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I have pos ANA and all other lupus test normal but have symptoms of lupus can you have lupus with only pos ANA test and other lupus test negative?

LUPUS: A low positive ANA alone may be non diagnostic. If all other labs are normal, it can be repeated in a 2-3 mth window. Lupus also has a list of criteria that needs to be met to fulfill the diagnosis. Follow up with your doctor and if still concerned see a rheumatologist. ...Read more

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Can you have lupus with a negative ANA test? What about other autoimmune disorders?

Can you have lupus with a negative ANA test? What about other autoimmune disorders?

ANA testing: ANA is a screening test for autoimmune disease, (generally present in 80-90% of cases). A higher titer over 1:160 is more significant. There are more definite testing for lupus such as anti-smith antibody and anti ds dna antbody. There are many more other specific testing for other specific autoimmune disorders. Syphilis and lyme disease can give false positive ANA test as well. See your md. ...Read more

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Unexplained high platelets (572), WBC (17.2), leukocytes, neutrophils, low hemaglobin. Bone marrow, jak2 and lupus test negative, ANA positive. Help?!

Reactive/ autoimmune: Discuss further with your hematologist. Certain conditions like iron deficiency , infection /inflammation vs autoimmune vs. Other solid tumor need to be ruled out. Need to check iron level, bcr/abl, imaging study like ct scan chest /abd/ pelvis will be needed. If you smoke - will suggest you to quit smoking., need to do work - up to find the anemia as well. If iron is low - GI w/u is needed. ...Read more

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I have fibromyalgia. I have many symptoms of autoimmune diseases.Lupus & RA test normal.ANA & CRP test are positive and elevated.What does this mean?

Exam: You should see a rheumatologist to undergo a full history and exam. No single test can diagnose a rheumatological disease. ANA alone is not indicative of sle. The titer and type is imp. High CRP again in a non specific sign of inflammation. So should see a rheumatologist and have this a exam. ...Read more

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Will mild lupus show up on a ANA test?

It depends: Lupus has many different symptoms. There are varieties of lupus limited to the skin. In these types, the ANA can be negative. However there are more severe forms of lupus, that can effect almost any part of the body. Commonly effected organs include the joints, kidneys, lungs, brain, and blood vessels. In these forms of lupus, the ANA test is almost always positive ...Read more

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Can ANA test be false negative for lupus?

Lupus: Has specific criteria for diagnosis, ANA is just one of them and canot be relied on by itself for a diagnosis. ...Read more

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Will my ANA test positive if my lupus is mild?

Yes: The degree of ANA positivity does not correlate with disease activity. ...Read more