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Not aware of any: Generally, stopping Lupron just allows the whole hypothalamic-pituitary-gonadal axis to start getting back to normal, with gradual increases in both testosterone and estrogen as the Lupron wears off. In some people who have been on multiple courses of lupron, or have been on it for a long time, there may not be recovery, and the low testosterone and estrogen may be permanent. ...Read more
Menopausal effects: Lupron injections are used for many reasons in gynecology, most commonly in the treatment of fibroids and endometriosis. Essentially, Lupron shuts down ovarian function and leads to a menopausal state. Therefore, side effects include hot flashes, vaginal dryness, mood swings, decreased libido, and bone loss. ...Read moreSee 1 more doctor answer
Hormone inhibitor: Lupron (aka leuprolide) inhibits the production of testosterone and estrogen from the testes and ovaries, respectively. It is used in the treatment of a number of things including endometriosis, prostate and breast cancer and inappropriately early puberty in kiddos, each of which is made worse by excessive testosterone or estrogen secretion. ...Read moreSee 1 more doctor answer
No time limit: It really depends upon its benefit to your husband. Men with metastatic disease can have long term benefit. ...Read more
Varies: There are three forms of lupron, one is a subcutaneous injection daily which will wear off very quickly. The second type is a depot form which last for approximately 30 days in the body, and lastly there is a 90 day form. A woman will usually ovulate 2 to 4 weeks after the effects of the Lupron has worn off. ...Read more
Depends/ indications: I agree with the prior answer in context, but want to weigh in on other uses. Studies show Lupron in the depot form is effective at shrinking fibroid volume by about 1/3 in 3 months. This gives a proven statistically lower blood loss in women preparing for surgical myomectomy. Also Lupron in the non-depot form is safe, effective and routinely used in stimulations for ivf. ...Read moreSee 1 more doctor answer
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