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Doctor insights on: Lupron Leuprolide Injection

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Dr. Mark Ingerman
157 Doctors shared insights

Leuprolide Acetate (Definition)

Leuprolide acetate is a GnRH stimulator which is a kind of women's ...Read more


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What is the risks for lupron (leuprolide) injections to induce menopause at 30 years old?

What is the risks for lupron (leuprolide) injections to induce menopause at 30 years old?

Minimal, if: Minimal risks if used appropriately for the right reasons, and for a limited period of time. A few symptoms, but no significant risks. It is not appropriate to treat a solid/septate ovarian mass with Lupron (leuprolide) without a firm diagnosis though. ...Read more

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How long should you wait after the 3 month Lupron (leuprolide) injection to try to conceive?

How long should you wait after the 3 month Lupron (leuprolide) injection to try to conceive?

Depends: Why are you taking the Lupron (leuprolide)? is the underlying condition such that it is safe to proceed? You need to discuss this with your doctor who I suppose operated on you to diagnose the condition. In general, yes, after 3 months passes you might start ovulating and it will be a chance to get pregnant ...Read more

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How long do lupron (leuprolide) injections work to increase chances of getting pregnant?

How long do lupron (leuprolide) injections work to increase chances of getting pregnant?

It depends: Lupron (leuprolide) does not directly improve pregnancy rates. It actually works to suppress ovulation and prevent pregnancy. There is a misperception that it can be used to improve pregnancy rates in people with endometriosis. Lupron (leuprolide) can be used as an adjunct in fertility treatments. If you have a fertility problem, it is best to see a specialist - a reproductive endocrinologist. ...Read more

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After having a 3 months dose of lupron (leuprolide) injection, after how long till my menstrual cycle be back to normal?

After having a 3 months dose of lupron (leuprolide) injection, after how long till my menstrual cycle be back to normal?

Variable: Lupron (leuprolide) suppresses estrogen production from the ovary. Ovulation usually does not occur but Lupron (leuprolide) is not considered a contraceptive hormone. Menstrual bleeding does not normally occur with Lupron (leuprolide) administration but periods should resume within six months of stopping this medication. ...Read more

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Had lupron (leuprolide) injection about a week and a half ago and have been having bad pelvic pain and a bad headache. How soon should this resolve?

Had lupron (leuprolide) injection about a week and a half ago and have been having bad pelvic pain and a bad headache. How soon should this resolve?

2-3 weeks after shot: Since Lupron (leuprolide) initially stimulates the receptors, it is common to have some pain (if that's the problem) for 2-3 wks after the injection. This shouldn't be a problem with subsequent injections. ...Read more

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If I had my last lupron (leuprolide) injection on dec 19th, and I'm trying to conceive. Will the effects continue this month or harm a possible implantation?

If I had my last lupron (leuprolide) injection on dec 19th, and I'm trying to conceive. Will the effects continue this month or harm a possible implantation?

It's safe: Lupron (leuprolide) is often used as a part of the preparation for an in vitro fertilization cycle. The medication is given in different dosages depending upon the purpose for it. But regardless, if you are able to ovulate, and conceive, it should not interfere with implantation, especially this long since your last dose. Good luck! ...Read more

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Is it common to develop ovarian cysts after a lupron (leuprolide) injection? Just had sn us w/ a 1.5cm cyst on r ovary, lupron (leuprolide) injection was on 10/30.

Is it common to develop ovarian cysts after a lupron (leuprolide) injection? Just had sn us w/ a 1.5cm cyst on r ovary, lupron (leuprolide) injection was on 10/30.

Not uncommon: Lupron (leuprolide) works initially by causing your pituitary gland to release fsh and lh. This explains why it is used in certain ivf protocols. In patients taking Lupron (leuprolide) for endometriosis patients can sometimes experience some worsening of their symptoms initially and then improvement after a couple of weeks. A 15 mm cyst is relatively small...Usually the follicle (cyst that contains an egg) reaches 20 mm. ...Read more

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Last mens was 10/29-11/2 w/a lupron (leuprolide) injection on 10/30. Started having vag bleeding w/ bad pelvic pain today, normal w/ lupron (leuprolide)? Making appt tues.

Last mens was 10/29-11/2 w/a lupron (leuprolide) injection on 10/30. Started having vag bleeding w/ bad pelvic pain today, normal w/ lupron (leuprolide)? Making appt tues.

Yes: Pelvic pain often gets worse the first two weeks after lupron (leuprolide). This is due to an increase in estrogen from a transient increase in pituitary fsh. This can cause vaginal bleeding also. After two weeks the fsh and estrogen level markedly drop and your pain and abnormal bleeding should improve. ...Read more

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I've had no period for a year thanks to lupron (leuprolide) injections I had administered for 6 months last year. Can I get pregnant currently?

I've had no period for a year thanks to lupron (leuprolide) injections I had administered for 6 months last year. Can I get pregnant currently?

Yes: If you're past the 12 weeks since your last injection, you can definitely get pregnant. If you don't want to be pregnant, make sure that you see doctor for birth control and wear condoms as well to prevent against std exposure. Good luck! ...Read more

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I have fibroids that are very painful and it's causing me to lose sleep and my gyno suggested lupron (leuprolide) injections what are the pros and cons? I am 42yrs old and my periods are getting more painful each month.

I have fibroids that are very painful and it's causing me to lose sleep and my gyno suggested lupron (leuprolide) injections what are the pros and cons? I am 42yrs old and my periods are getting more painful each month.

Shrinkage: Lupron (leuprolide) will shrink your fibroids, but they will grow back after the medication is stopped. In addition, it will cause signs and symptoms of the menopause. Depending on the size of the fibroids, luprom is frequently used to shrink fibroids prior to definitive surgery to make the surgery easier. ...Read more

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Started mens 10/30 & had a 3 month lupron (leuprolide) injection yesterday. Soaked pads in 1hr30min, been very nauseas & vomiting, headache, & dry mouth. Normal?

Started mens 10/30 & had a 3 month lupron (leuprolide) injection yesterday. Soaked pads in 1hr30min, been very nauseas & vomiting, headache, & dry mouth. Normal?

Normal side effects: Some of the symptoms you mentioned are among other side effects that Lupron (leuprolide) causes. Nausea, vomiting, head ache and dry mouth are more serious side effects. It would be wise to consult with your prescribing physician about these. ...Read more

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Lupron (leuprolide) injection yesterday and having heavy bleeding, headache, increased pelvic pain, dry mouth, nausea & vomiting. Is this normal reaction to lupron (leuprolide)?

Lupron (leuprolide) injection yesterday and having heavy bleeding, headache, increased pelvic pain, dry mouth, nausea & vomiting. Is this normal reaction to lupron (leuprolide)?

Adverse reactions: Even thought some of the reactions you report sound common, the fact that you report having several significant reactions, including the dry mouth which seems to be very soon to present since the injection, I would urge you to visit the prescribing doctor so that you may discuss your reactions addressing the severity as well as the duration, also ruling out other possible causes. ...Read more

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What are the medical uses of lupron (leuprolide) depot injections?

What are the medical uses of lupron (leuprolide) depot injections?

Endometriosis. ..: Depo-lupron monthly or 3-month injections are used for women with endometriosis or chronic pelvic pain, men with prostate cancer, and children with puberty too young. It may be used to shrink uterine fibroids before surgery. Depo-lupron is used in fertility treatment to prevent ovulation in frozen embryo transfer cycles & egg donor recipients, and can be used before ivf in women with endometriosis. ...Read more

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I have been on the 3 month lupron (leuprolide) depot injection but still having multiple periods. Does this mean I have been ovulating through the shot?

I have been on the 3 month lupron (leuprolide) depot injection but still having multiple periods. Does this mean I have been ovulating through the shot?

Possibly: Some women will ovulate through lupron (leuprolide). Since you are still getting periods, you should discuss increasing the dose with your doctor. ...Read more

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Can someone explain how lupron (leuprolide) depot injections can help in the treatment of premenstraul dysphoric disotder?

Supression of ovarie: It causes suppression of ovaries and ovulation.It is caused by reduction of lh (leutenising hormone)and fsh (follicle stimulating hormone) both produced by the pituatary gland. And that causes reduction in estrogen level and thereby suppressing ovaries and ovulation. ...Read more

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Had lupron (leuprolide) injection on 10/30 for endometriosis and hqve follow up 1/17 to set up totwl hysterectomy. Started having pelvic pain today, sould I reschedule my follow up?

Had lupron (leuprolide) injection on 10/30 for endometriosis and hqve follow up 1/17 to set up totwl hysterectomy. Started having pelvic pain today, sould I reschedule my follow up?

No: Keep your appointment. The Lupron (leuprolide) injections can last for a month or 3 months depending on your dose. If you got a 1 month injection, your endometriosis may be regrowing. Could also be other causes: uti, intestinal - there is a lot of overlap in the nerves to the pelvic organs (bladder, uterus/ovaries, colon) and it can be hard to differentiate which organ system is causing the pain. ...Read more

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Lupron (leuprolide) injection 10/29 for endometriosis, follow up appt to start process for me to have a total hysterectomy. Started to have pelvic pain a couple of days ago. What can I do for the pelvic pain at home between now and my appt?

Lupron (leuprolide) injection 10/29 for endometriosis, follow up appt to start process for me to have a total hysterectomy. Started to have pelvic pain a couple of days ago. What can I do for the pelvic pain at home between now and my appt?

Aleve (naproxen): You can use aleve (naproxen) 2 2x per day if appliicable for pain control, and if necessary start back on an ocp; iot depends on if it was the trhree month shot, if so it should still be working and may be yoiur bladder. ...Read more

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Headaches, acid reflux, fatigue and muscle aches. Are these symptoms due to my 3 month lupron (leuprolide) depot injection?

Headaches, acid reflux, fatigue and muscle aches. Are these symptoms due to my 3 month lupron (leuprolide) depot injection?

Maybe: All these are symptoms that patients complain on Depo-Provera Lupron (leuprolide) but have not been substantiated by the company. My experience is that when you take hormone replacement back they get better. Ask your md if you could have add-back therapy, although typically this is done after 6 mo of Depo-Provera Lupron (leuprolide) for endometriosis or cancer. ...Read more

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Lupron (leuprolide) 11.25 3mnt injection feb 12, cycle was 10days period lasted 5 of those, last period may 12 was 4 days, could I be pregnant? Symptoms seem to be

Lupron (leuprolide) 11.25 3mnt injection feb 12, cycle was 10days period lasted 5 of those, last period may 12 was 4 days, could I be pregnant? Symptoms seem to be

Lupron (leuprolide): Lupron (leuprolide) lasts 3 months. While its very unlikely your pregnant, do a test. More likely, your not getting a period because of the the lupron (leuprolide). ...Read more

Dr. AARATHI Cholkeri-Singh
168 Doctors shared insights

Lupron (Definition)

Lupron is a GnRH stimulator which is a kind of women's ...Read more


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