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Doctor insights on: Lupron Leuprolide Depot

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Lupron (leuprolide) depot not helping. What are some alternatives?

Lupron (leuprolide) depot not helping. What are some alternatives?

Lupron for what?: Need more information. For what problem are you on Lupron? What symptoms are you having that are not going away on Lupron. Best wishes! ...Read more

Leuprolide Acetate (Definition)

Leuprolide acetate is a GnRH stimulator which is a kind of women's ...Read more


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What are the medical uses of lupron (leuprolide) depot injections?

What are the medical uses of lupron (leuprolide) depot injections?

Endometriosis. ..: Depo-lupron monthly or 3-month injections are used for women with endometriosis or chronic pelvic pain, men with prostate cancer, and children with puberty too young. It may be used to shrink uterine fibroids before surgery. Depo-lupron is used in fertility treatment to prevent ovulation in frozen embryo transfer cycles & egg donor recipients, and can be used before ivf in women with endometriosis. ...Read more

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Lupron (leuprolide) depot not helping. What are some alternatives?

Lupron (leuprolide) depot not helping. What are some alternatives?

Assume Pelvic Pain: ? Diagnosis endometriosis and pain. If Lupron (leuprolide) is not helping, the pain is either coming from very severe endo, or from another source. A common associated pain is from the inguinal region and is often associated with endo. Surgery to correct this relieves pain in more than 80%. There are other potential causes of pain that should be evaluated. Seek pelvic pain/endo specialist for more help. ...Read more

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What are the side effects of lupron (leuprolide) depot?

What are the side effects of lupron (leuprolide) depot?

Side effects: Lupron (leuprolide) side effects are hot flashes and head aches. If taken for longer than 6 months some reversible bone loss can be found with bone scans. ...Read more

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How does lupron (leuprolide) depot work for endometriosis?

How does lupron (leuprolide) depot work for endometriosis?

In the brain: Receptors in the brain get saturated to a that point the pulses of gnrh cannot stimulate the ovarian production of estrogen. ...Read more

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How severe do the side effects of lupron (leuprolide) depot?

How severe do the side effects of lupron (leuprolide) depot?

Usually Mild: When I treat patients with Depo-Provera Lupron (leuprolide) (for instance for endometriosis) I usual;y use add back therapy, this is a second medicine used to prevent the side effects from lupron (leuprolide). The addback usually reduces or gets rid of any hot flashes, any vaginal dryness, or any mood swings. So in this way I usually prevent side effects from ever occurring. ...Read more

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What are the side effects of lupron (leuprolide) depot 11.25 mg?

What are the side effects of lupron (leuprolide) depot 11.25 mg?

Low estrogen: They're typically those that are related to low estrogen. These are hot flashes, vaginal dryness, difficulty with memory, sleep disturbances, and bone demineralization. ...Read more

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Is it safe to be receiving lupron (leuprolide) depot shots for 11 years?

Is it safe to be receiving lupron (leuprolide) depot shots for 11 years?

Depo-Lupron: It is incredibly unusual for a doctor to recommend treatment with depo-lupron for 11 years. This medication is not considered a long-term treatment of any gynecological condition. It's normally used for 6-12 months at a time to control endometriosis, shrink fibroids ; a few other situations. The main concern is poor bone health. Although other complications are possible from early menopause. ...Read more

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When considering the use of lupron (leuprolide) depot 11.25 3 month injection for precious puberty, would you ever use that dose every 28 days instead? Why/why not

When considering the use of lupron (leuprolide) depot 11.25 3 month injection for precious puberty, would you ever use that dose every 28 days instead? Why/why not

Consult your doctor: For precocious puberty, the 11.25 mg Lupron (leuprolide) every 3 months is sufficient 90-95% of the time. If her breasts are getting bigger or she continues to grow too rapidly, your daughter's ped endo might consider giving the Lupron (leuprolide) every 2 months but it is usually not necessary to give it more often as it is designed to be released slowly enough to last 3 months ...Read more

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Is it okay to try lupron (leuprolide) depot shot can we try for having kids?

Is it okay to try lupron (leuprolide) depot shot can we try for having kids?

Yes, not together: It's safe to use Lupron (leuprolide) depot for limited treatments and it's okay to try having kids before or after, you just can't do the two at the same time. ...Read more

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After taking lupron (leuprolide) depot 11.25, when should I expect to get periods?

3 months: Lupron (leuprolide) Depot 11.25 is usually a 3 month dose, so you'd not expect to have periods until it wears off. ...Read more

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I was on lupron (leuprolide) depot shots for 6 months--when should I expect a period to return?

I was on lupron (leuprolide) depot shots for 6 months--when should I expect a period to return?

Soon: Generally if you took a monthly shot, your period should return about 1-2 months after the last shot. However that is assuming your periods were regular to begin with and nothing in your body changed while on lupron (leuprolide). Otherwise your period should revert back to normal. ...Read more

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Lupron (leuprolide) depot not covered by ins. Pharmacy will not accept medication discount from drug company. Any lower cost alternatives for tx of endometriosis?

Endo: First off, I wouldn't give up so easily. Call the pharmaceutical company and ask for help obtaining your prescription from a different pharmacy. But if that fails, there are other less effective options: Depo-Provera provera, (medroxyprogesterone) continuous low dose birth control pills, and danocrine. And, I've seen people get pain relief from acupuncture! also an herbal supplement called "pine bark extract" may help. ...Read more

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How long does it take for lupron (leuprolide) depot to get out of your system, trying to conceive?

How long does it take for lupron (leuprolide) depot to get out of your system, trying to conceive?

Depends on the dose: If you had the three month it could be up to four months. If you had the monthly, more than likely ok at six weeks. ...Read more

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I have been on the 3 month lupron (leuprolide) depot injection but still having multiple periods. Does this mean I have been ovulating through the shot?

I have been on the 3 month lupron (leuprolide) depot injection but still having multiple periods. Does this mean I have been ovulating through the shot?

Possibly: Some women will ovulate through lupron (leuprolide). Since you are still getting periods, you should discuss increasing the dose with your doctor. ...Read more

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Does lupron (leuprolide) depot cause severe acne?

Does lupron (leuprolide) depot cause severe acne?

No: Lupron (leuprolide) disconnects the association of the brain with the ovaries or the brain to the testicles. This in turn suppresses fsh/lh levels. Subsequently lowering estrogen and testosterone levels. ...Read more

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When taking lupron (leuprolide) depot what can be done to prevent bone loss?

When taking lupron (leuprolide) depot what can be done to prevent bone loss?

Medications: Lupron causes bone loss by markedly decreasing testosterone and estrogen production in the body. Estrogen loss seems to be more important for this effect. A variety of drugs including alendronate, residronate, ibandronate, zoledronic acid and Denosumab can prevent bone loss. Normal vitamin d and calcium intake are to be continued. ...Read more

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How long does it usually take for lupron (leuprolide) depot to begin altering a woman's menstrual cycle?

How long does it usually take for lupron (leuprolide) depot to begin altering a woman's menstrual cycle?

Different for All: In general, Lupron (leuprolide) will stop menstruations but exactly when it takes effect is a bit debatable and likely different for all women. In general the effect is seen after 2 weeks (following an initial hormonal surge). ...Read more

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Can someone explain how lupron (leuprolide) depot injections can help in the treatment of premenstraul dysphoric disotder?

Supression of ovarie: It causes suppression of ovaries and ovulation.It is caused by reduction of lh (leutenising hormone)and fsh (follicle stimulating hormone) both produced by the pituatary gland. And that causes reduction in estrogen level and thereby suppressing ovaries and ovulation. ...Read more

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Can lupron (leuprolide) depot cause fatigue, memory loss?

Can lupron (leuprolide) depot cause fatigue, memory loss?

Yes: Lupron (leuprolide) can cause fatigue and short term memory loss. Also taken beyond six months can cause bone loss. ...Read more

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Can lupron (leuprolide) depot cause an increase in blood platelets?

Can lupron (leuprolide) depot cause an increase in blood platelets?

Yes: There are reports showing that depo-lupron can decrease platelet production. If you plan on being on it for extended periods of time than you should measure your platelets on a regular basis especially if you have other risk factors that lower platelet counts. ...Read more

Dr. AARATHI Cholkeri-Singh
168 Doctors shared insights

Lupron (Definition)

Lupron is a GnRH stimulator which is a kind of women's ...Read more


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