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Doctor insights on: Lupron Depot 3 Month Medication

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Dr. Jan Lei Iwata
157 Doctors shared insights

Leuprolide Acetate (Definition)

Leuprolide acetate is a GnRH stimulator which is a kind of women's ...Read more


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I have been diagnosed with endometriosis I have had two laproscopy and also been treated with 2 six month doses of lupron depot to help control the pain I also have mirena my doctor tells me there is nothing else he can do for the pain I constantly have p

I have been diagnosed with endometriosis I have had two laproscopy and also been treated with 2 six month doses of lupron depot to help control the pain I also have mirena my doctor tells me there is nothing else he can do for the pain I constantly have p

Endometriosis: First, has your doctor treated all visible disease at each laparoscopy - or used it mainly for diagnosis? If the latter, you might benefit from seeing a specialist surgeon. If 'yes, ' has your doctor helped you rule out other possible causes of pain (besides endometriosis?) bladder or intestinal disease? A pain management specialist may also be able to help. Best wishes! ...Read more

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My son had an allergic reaction (severe rash & hives) to a supprelin implant. Is it likely he will react to lupron-depot too?

My son had an allergic reaction (severe rash & hives) to a supprelin implant. Is it likely he will react to lupron-depot too?

Maybe...but unsure.: Supprelin la (histrelin) is a Histrelin Acetate implant; whereas Lupron depot is a Leuprolide Acetate suspension. Obviously there is worthwhile concern on your part about this alternative therapy for central precocious puberty in that both medications act to suppress development of puberty artificially. Regardless, the best source of information on this matter is your son's endocrinologist. Contact her today. ...Read more

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Lupron (leuprolide) depot not covered by ins. Pharmacy will not accept medication discount from drug company. Any lower cost alternatives for tx of endometriosis?

Lupron (leuprolide) depot not covered by ins. Pharmacy will not accept medication discount from drug company. Any lower cost alternatives for tx of endometriosis?

Endo: First off, I wouldn't give up so easily. Call the pharmaceutical company and ask for help obtaining your prescription from a different pharmacy. But if that fails, there are other less effective options: Depo-Provera provera, (medroxyprogesterone) continuous low dose birth control pills, and danocrine. And, I've seen people get pain relief from acupuncture! also an herbal supplement called "pine bark extract" may help. ...Read more

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My 7 year old daughter has been diagnosed with cpp and her doctor wants to start her on lupron (leuprolide) depot ped 7.5mg monthly. How safe is this medication?

My 7 year old daughter has been diagnosed with cpp and her doctor wants to start her on lupron (leuprolide) depot ped 7.5mg monthly. How safe is this medication?

Safe up to 55 lbs wt: Central precocious puberty requires both early development of both pubic hair + breast development. Should be safe for girls weighing up to 55 lbs. Should be given regularly every 28 days. Consider 2nd opinion if daughter is older than age-8-years. ...Read more

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When considering the use of lupron (leuprolide) depot 11.25 3 month injection for precious puberty, would you ever use that dose every 28 days instead? Why/why not

When considering the use of lupron (leuprolide) depot 11.25 3 month injection for precious puberty, would you ever use that dose every 28 days instead? Why/why not

Consult your doctor: For precocious puberty, the 11.25 mg Lupron (leuprolide) every 3 months is sufficient 90-95% of the time. If her breasts are getting bigger or she continues to grow too rapidly, your daughter's ped endo might consider giving the Lupron (leuprolide) every 2 months but it is usually not necessary to give it more often as it is designed to be released slowly enough to last 3 months ...Read more

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Does green coffee extract really work? I started taking some after gaining 10 lbs in one month after taking depot lupron (leuprolide)

Does green coffee extract really work? I started taking some after gaining 10 lbs in one month after taking depot lupron (leuprolide)

Weight gain on Lupro: Unfortunately a commonly seen side effect of Lupron (leuprolide) is weight gain (mimics menopause). I doubt that green coffee extract will help you lose weight, but it won't hurt. You have to increase your excersize daily, and reduce food intake while on the medication. It will take some time to lose weigh once you stop lupron (leuprolide). ...Read more

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I have been on the 3 month lupron (leuprolide) depot injection but still having multiple periods. Does this mean I have been ovulating through the shot?

I have been on the 3 month lupron (leuprolide) depot injection but still having multiple periods. Does this mean I have been ovulating through the shot?

Possibly: Some women will ovulate through lupron (leuprolide). Since you are still getting periods, you should discuss increasing the dose with your doctor. ...Read more

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I was on lupron (leuprolide) depot shots for 6 months--when should I expect a period to return?

I was on lupron (leuprolide) depot shots for 6 months--when should I expect a period to return?

Soon: Generally if you took a monthly shot, your period should return about 1-2 months after the last shot. However that is assuming your periods were regular to begin with and nothing in your body changed while on lupron (leuprolide). Otherwise your period should revert back to normal. ...Read more

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Lupron (leuprolide) depot not helping. What are some alternatives?

Lupron (leuprolide) depot not helping. What are some alternatives?

Lupron for what?: Need more information. For what problem are you on Lupron? What symptoms are you having that are not going away on Lupron. Best wishes! ...Read more

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Lupron (leuprolide) depot not helping. What are some alternatives?

Lupron (leuprolide) depot not helping. What are some alternatives?

Assume Pelvic Pain: ? Diagnosis endometriosis and pain. If Lupron (leuprolide) is not helping, the pain is either coming from very severe endo, or from another source. A common associated pain is from the inguinal region and is often associated with endo. Surgery to correct this relieves pain in more than 80%. There are other potential causes of pain that should be evaluated. Seek pelvic pain/endo specialist for more help. ...Read more

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What are your experiences with prescribing depot lupron (leuprolide)?

What are your experiences with prescribing depot lupron (leuprolide)?

Terrible: Hate the drug. It has bad side effects and very few indications in my opinion. If it's given for endometriosis or pain, there are other treatments. The most effective treatment of endo is surgical excision. This can cure the disease but there are few providers capable of this procedure. Recurrent pain after surgery needs to be addressed but Lupron (leuprolide) is not the answer. Ther are a few indication. ...Read more

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What are the side effects of lupron (leuprolide) depot?

What are the side effects of lupron (leuprolide) depot?

Side effects: Lupron (leuprolide) side effects are hot flashes and head aches. If taken for longer than 6 months some reversible bone loss can be found with bone scans. ...Read more

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How does lupron (leuprolide) depot work for endometriosis?

How does lupron (leuprolide) depot work for endometriosis?

In the brain: Receptors in the brain get saturated to a that point the pulses of gnrh cannot stimulate the ovarian production of estrogen. ...Read more

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How severe do the side effects of lupron (leuprolide) depot?

How severe do the side effects of lupron (leuprolide) depot?

Usually Mild: When I treat patients with Depo-Provera Lupron (leuprolide) (for instance for endometriosis) I usual;y use add back therapy, this is a second medicine used to prevent the side effects from lupron (leuprolide). The addback usually reduces or gets rid of any hot flashes, any vaginal dryness, or any mood swings. So in this way I usually prevent side effects from ever occurring. ...Read more

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What are the side effects of lupron (leuprolide) depot 11.25 mg?

What are the side effects of lupron (leuprolide) depot 11.25 mg?

Low estrogen: They're typically those that are related to low estrogen. These are hot flashes, vaginal dryness, difficulty with memory, sleep disturbances, and bone demineralization. ...Read more

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Is it safe to be receiving lupron (leuprolide) depot shots for 11 years?

Is it safe to be receiving lupron (leuprolide) depot shots for 11 years?

Depo-Lupron: It is incredibly unusual for a doctor to recommend treatment with depo-lupron for 11 years. This medication is not considered a long-term treatment of any gynecological condition. It's normally used for 6-12 months at a time to control endometriosis, shrink fibroids ; a few other situations. The main concern is poor bone health. Although other complications are possible from early menopause. ...Read more

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What are the effects of depot lupron (leuprolide)?

What are the effects of depot lupron (leuprolide)?

Few: Low estrogen causes hot flashes, dry vagina, and osteoporosis (week bones).
Local reaction at the injection site.
Some of the effects of low estrogen can be minimized by estrogen add back therapy (taking very small amount of estrogen). ...Read more

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What are the medical uses of lupron (leuprolide) depot injections?

What are the medical uses of lupron (leuprolide) depot injections?

Endometriosis. ..: Depo-lupron monthly or 3-month injections are used for women with endometriosis or chronic pelvic pain, men with prostate cancer, and children with puberty too young. It may be used to shrink uterine fibroids before surgery. Depo-lupron is used in fertility treatment to prevent ovulation in frozen embryo transfer cycles & egg donor recipients, and can be used before ivf in women with endometriosis. ...Read more

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Is it okay to try lupron (leuprolide) depot shot can we try for having kids?

Is it okay to try lupron (leuprolide) depot shot can we try for having kids?

Yes, not together: It's safe to use Lupron (leuprolide) depot for limited treatments and it's okay to try having kids before or after, you just can't do the two at the same time. ...Read more

Dr. AARATHI Cholkeri-Singh
168 Doctors shared insights

Lupron (Definition)

Lupron is a GnRH stimulator which is a kind of women's ...Read more