Doctor insights on:
Lung Metastases From Liposarcoma
My uncle has been identified with non small cell lung cancer and it is metastases (4th stage). He is just 48 year old. Is there any cure?
Most time no cure fo: I am so sorry to hear this bad news. I have several patients who were diagnosed stage 4 lung cancer in their 40s, althought most our patients are 60-80s. In aptients with lung cancer who are young or never smoked, the likelihood of having a particularly gene mutation is high, so it is critical to have the patient's gene checked. If certain gene mutation idenfied, a tailored tgerapy can be given. ...Read moreSee 2 more doctor answers
Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more
Can medullary thyroid carcinoma metastase to the lungs while being undetectable on a thyroid sonogram? Or by that time throyd nod are present?
Theoretically yes: But unlikely. Theoretically all you need is a tiny group of cancer cells at the microscopic level to have the capability to metastasize. However in practice there is almost always a detectable nodule before it metastasizes because the cancer needs to be more advance and aggressive. ...Read more
Fair: There are several factors that affect prognosis. First the type of lung cancer. Is it small cell or non-small cell. Second, has there been a check on the molecular markers on the tumor (egfr, alk, ros 1?) there are targeted agents for those tyoe of tumors and patients do much better than the average. Discuss with your oncologist treatment options prognosis. Avoid internet for prognosis. ...Read moreSee 1 more doctor answer
Clinical trial: Clinical trial or standard chemotherapy. Bone mets can be treated with bisphosphonate (zometa) or Denosumab (xgeva). Mri of the brain should evaluate for brain mets. Trials: http://clinicaltrials.Gov/ct2/results?Term=small+cell+lung+cancer&recr=open&no_unk=y standard of care chemotherapy is a 2 drug combination with a "platinum". ...Read more
My mum, 67 , was diagnosed with colon cancer with liver metastases, lesions in lungs and kidneys. Starting folfox tomorrow?? Life expectancy?
Not enough: Need to assess for Kras and Nras mutation IF she is wild type she should receive FOLFIRI and Erbitux If she has mutation the treatment of choice FOLFOX and Avastin Life expex 22 - 26 months... If responsive disease can be extended with other agents and survival can extend several years. New agents add to OS sequencing of therapy is important to extend Overal survival ...Read more
What can we expect from a stage 4 lung cancer patient with bone metastases- what can be done in case all treatments are ruled out?
Biomarkers in lungCA: For stage 4 non-small cell lung cancer -- specifically adenocarincoma -- i would check the biomarkers alk and egfr. The response rate with oral drugs for those targets is ~80% vs. 20% with chemo. Bone mets can be treated with bisphosphonate (zometa) or Denosumab (xgeva). Palliative care provided early has a survival benefit. Ref: temel et al. Nejm http://www.Nejm.Org/doi/pdf/10.1056/nejmoa1000678. ...Read moreSee 1 more doctor answer
Urgent, doctors :'( my mom has metastases liver cancer, lung and bone nearby left thigh found tumors. Just found out few days ago, is stage 4. How?
This is too: Common. Some cancers are quiet until they infest other organs, and it is these organs working poorly or hurting that causes the cancer to be known. Some cancers can have life extended by treatment (prostate and breast), others can be treated to relieve symptoms. But for most, it means time to focus on comfort and symptom relief rather than rigorous treatment. ...Read moreSee 2 more doctor answers
Yes: Radiation is often used to alleviate many symptoms from cancer that has spread to organs and that includes liver and bone. Not every spot involved has to be treated only those causing some sort of problem. If the patient only has one small liver metastasis for example more aggressive treatment with radiosurgery can be considered. ...Read moreSee 1 more doctor answer
What is metastasis and at what stage during the devolopment of lung cancer does it start to occur?
Distant spread: A tumor is said to have metastasized when it spreads to a distant site through lymphatics or blood vessels. The molecular changes in the tumor associated with ability to metastasize vary with different tumors and are not clearly defined. In some types of lung cancers, metastases can occur even before cancer becomes detectable by x-ray. ...Read moreSee 1 more doctor answer
A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site ...Read more
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