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Doctor insights on: Lubiprostone Medication

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When is the onset of action and peak action of the drug, amitiza (lubiprostone)? For once daily dosing, what time of day should it be taken?

When is the onset of action and peak action of the drug, amitiza (lubiprostone)? For once daily dosing, what time of day should it be taken?

A couple of hours: Amitiza (lubiprostone) can help one have a bowel movement in a couple of hours. It can be taken at anytime, but probably works better if taken with a meal that includes water or beverages. That means one should not take Amitiza (lubiprostone) without knowing where the nearest bathroom is (for 1-4 hours after taking the medicine). ...Read more

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How. & for what is amitiza (lubiprostone) to be taken?

How. & for what is amitiza (lubiprostone) to be taken?

Constipation: Generally Amitiza (lubiprostone) is prescribed for chronic constipation taken as a pill twice daily with food and water. ...Read more

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What is the difference between amitiza (lubiprostone) and lizness? Preference?

What is the difference between amitiza (lubiprostone) and lizness? Preference?

Amitiza (lubiprostone) vs Linzess: Both r used for irs w/constipation ; for chronic constipation of unknown cause. Price may be a factor as may ins co's formulary. Dose of Amitiza (lubiprostone) may need adjustment in presence of liver disease. Given these factors, it is prescribing doc's preference. ...Read more

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Why is amitiza (lubiprostone) described in the literature as being "for women"?

Why is amitiza (lubiprostone) described in the literature as being "for women"?

Testing: It has been tested and determined to be safe in men and women for "chronic iatrogenic constipation". It is approved for women with irritable bowel but there hasn't been enough testing in men to get the approval or show it is beneficial. ...Read more

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Will taking amitiza (lubiprostone) cause body aches?

Will taking amitiza (lubiprostone) cause body aches?

Not common...: ...but I have seen that complaint in some of my patients. Only way to tell is to stop the Amitiza (lubiprostone) & see if those aches go away. ...Read more

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Can amitiza (lubiprostone) cause tachycardia?

Can amitiza (lubiprostone) cause tachycardia?

Possibly: Amitiza (lubiprostone) has active ingredients of Lubiprostone commonly reported side effects of Amitiza (lubiprostone) include breathing difficulty, nausea, chest pain, pain, constipation.

Tachycardia
tachycardia has been reported by people with high blood pressure, depression, schizophrenia, pain, and osteoporosis who use this drug. Advise your physician of any adverse reactions. ...Read more

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Which is better for gastroparesis amitiza (lubiprostone) or linzess?

Which is better for gastroparesis amitiza (lubiprostone) or linzess?

Gastroparesis: Have you already been diagnosed with gastroparesis? Documentation of delayed emptying of gastric contents is required before treatment. All patients with symptoms of gastroparesis which include nausea, vomiting, early satiety &fullness/bloating need to be screened for diabetes mellitus, hypothyroidism, neurological disease, autoimmune disease, past surgery. Please see your MD for a full exam. ...Read more

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Why shouldn't you take amitiza (lubiprostone) with a bowel obstruction?

Why shouldn't you take amitiza (lubiprostone) with a bowel obstruction?

AmitizaTab: This drug is for the treatment chronic idiopathic constipation. If you have a bowel obstruction this has to be removed to allow your stool to go through the colon. If the obstruction is due only from stool compaction then the best way to clear the bowel is. By means of an enema or a suppository. If constipation persists then AmitizaTab may be of value but you should see your doctor to make that dec ...Read more

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What is the difference between peri-colace, amitiza, (lubiprostone) and miralax?

What is the difference between peri-colace, amitiza, (lubiprostone) and miralax?

Explanation of lax: colace (docusate sodium) is not a laxative, just a softener-acts a litle like adding slipperyness to stool so it comes out easy-no stimulants
miralax is a lavage, so it just goes thru your pipes and takes everything with it. So it acts like a laxative but not by stimulation of the intestines
amitiza (like Linzess) simply interferes with absorption of water from the colon, making the stools more moist ...Read more

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Was put on amitiza (lubiprostone) for constipation/ibd how long before I should see improvement. Will I still have flares?

Was put on amitiza (lubiprostone) for constipation/ibd how long before I should see improvement. Will I still have flares?

IBS: You should feel better on amitiza (lubiprostone). On average it will take about 2 weeks to see full response. Even with good response to medication you will have occasional flare ups depending on your level of anxiety or stress. Just relaxed and you be fine. ...Read more

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Can I drink prune juice while taking amitiza (lubiprostone)?

Can I drink prune juice while taking amitiza (lubiprostone)?

Yes: They should not interact. Just keep an eye on whether the combination works too well in which case you may get some diarrhea. ...Read more

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Can I take linzess or amitiza (lubiprostone) even with gallstones?

Can I take linzess or amitiza (lubiprostone) even with gallstones?

Yes: Having gall stones should not preclude your use of these medications, but note, you should get your gall stones treated so they do not cause serious issues in the future. Best wishes. ...Read more

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My doctor gave me samples of amitiza (lubiprostone) 8mcg to try for constipation but didn't explain how to take. Once or twice daily?

My doctor gave me samples of amitiza (lubiprostone) 8mcg to try for constipation but didn't explain how to take. Once or twice daily?

Get appropriate dose: Doctors define constipation as stools less frequently than once every 3-4 days. Patients feel they are "constipated" when passing hard or small volume stool, or they feel full ; bloated. Had an x-ray to show you're not blocked? Do we know if your gut is sluggish or your rectum works correctly--these can be tested for. Call the prescribing doc for the correct starting dose appropriate to your case. ...Read more

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Is amitiza (lubiprostone) a laxative and how does it affect sibo breath test if I take it a week before. Also how long does it take amitiza (lubiprostone) 8mcg to work?

Is amitiza (lubiprostone) a laxative and how does it affect sibo breath test if I take it a week before. Also how long does it take amitiza (lubiprostone) 8mcg to work?

Yes and no: Amitiza (lubiprostone) is a novel type of "laxative". Technically speaking, it is a locally acting chloride channel activator in the gut. It should not affect the breath test (which measures for bacterial overgrowth). It's onset of action can range from a few minutes to a few hours dependent upon your motility. ...Read more

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What happens when amitiza (lubiprostone) or linzess is used in patient with existing intestinal obstruction?

What happens when amitiza (lubiprostone) or linzess is used in patient with existing intestinal obstruction?

Should not be used: In a proven intestinal obstruction, which needs physician supervised care (even surgery). Amitiza (lubiprostone) (Lubiprostone) irlinzess (linaclotide) are the medications for chronic constipation, due to drugs, ibs etc contraindicated in intestinal obstruction ...Read more

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Upper abdominal pn, seeing tertiary GI in a few weeks. Gone on for many mths, would like all good suggestions. On Librax, & Amitiza (lubiprostone) & better w/ liq.

Upper abdominal pn, seeing tertiary GI in a few weeks. Gone on for many mths, would like all good suggestions. On Librax, & Amitiza (lubiprostone) & better w/ liq.

Exam: GI specialist, blood testing, upper endoscopy, abdominal ultrasound. You may have IBS, GERD, gallbladder/panreastic disease, gastritis, ulcer or pancreatic illness. Sorry, but this is the best information I can give: I would avoid aspirin, alcohool, Advil and Aleve (naproxen). You can try OTC Mylanta or Pepcid to reduce stomach acid until seen. Alcohol and NSAIDS/-avoid. ...Read more

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Why was zelnorm for IBS pulled off market? Is linzess or amitiza (lubiprostone) the same? I'm confused & nervous as I just started taking linzess

Why was zelnorm for IBS pulled off market? Is linzess or amitiza (lubiprostone) the same? I'm confused & nervous as I just started taking linzess

IBS: Bental may be effective. Amitiza (lubiprostone) is for idiopathic constipation and not indicated. You should see a gastroenterologist for more help. ...Read more

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I'm only 35 and can't hold in my urine. I'm on plaquenil, amitiza, (lubiprostone) meloxicam and myfortic. Can any of these be the cause of my incontinence?

I'm only 35 and can't hold in my urine. I'm on plaquenil, amitiza, (lubiprostone) meloxicam and myfortic. Can any of these be the cause of my incontinence?

No: None of the meds have incontinence of urine as a side effect. Since you are on immunosuppressant, which organ was replaced? Could you have injury to, the urinary sphincter? This requires an eval, by urologist to determine the cause. ...Read more

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Are propranolol, synthroid, zyrtec, & amitiza (lubiprostone) gluten free? I am on gluten free diet

Are propranolol, synthroid, zyrtec, & amitiza (lubiprostone) gluten free? I am on gluten free diet

Most likely: Gluten is not usually used in formulating any medication. However given that your medications are likely generic, there is no 100% sure way to tell. In general, I would say no, but if you are unsure, read the ingredient label and ask your pharmacist to check if you have doubts. ...Read more

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Can sronyx cause cramping a mild back pain? I just started it for two days. Also started amitiza (lubiprostone) and librax on 4/16 and 2xs a day.

Can sronyx cause cramping a mild back pain? I just started it for two days. Also started amitiza (lubiprostone) and librax on 4/16 and 2xs a day.

No: Neurological symptoms like numbness and extremity weakness tend to predominate over pain. Post traumatic syringomyelia can present with pain from a herniated disc or a fracture deformity that caused the syrinx but a de novo syrinx is usually not painful. Make sue you get a contrast MRI to rule out spinal cord tumor. ...Read more

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Is amitiza (lubiprostone) or linzess safer for long term use for ibs? 18 year old male with Wolff-Parkinson-White syndrome.

Is amitiza (lubiprostone) or linzess safer for long term use for ibs? 18 year old male with Wolff-Parkinson-White syndrome.

Ok: Neither are contraindicated for WPW but Amitiza (lubiprostone) has no black box warnings and Linzess does - since clinical experience with both is limited, i'd go with the former. ...Read more

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Is it concerning if I started amitiza (lubiprostone) and now have a full bladder (increased urination) every hour with no change in fluid intake?

Is it concerning if I started amitiza (lubiprostone) and now have a full bladder (increased urination) every hour with no change in fluid intake?

Very unusual...: I have never heard of this side effect from the drug in question, nor is it identified in the pdr as a significant adverse reaction. Perhaps the two issues are coincidental, so that your polyuria (urinary frequency) might then deserve further medical attention (rule out uti, high blood sugar, passing stones, etc). You can also stop the Amitiza (lubiprostone) ; see if the increased urination returns to baseline. ...Read more

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I have cronic constipation and diagnosed w ibs. I take amitiza (lubiprostone) but would prefer a treatment that provided a more normal stool and is less "urgent".

I have cronic constipation and diagnosed w ibs. I take amitiza (lubiprostone) but would prefer a treatment that provided a more normal stool and is less "urgent".

Ibs: If you have ibs and not happy with amitiza, (lubiprostone) you can try Linzess this is relatively new medication and many of my patients have good results. I would still take fiber supplement and increase exercise and hydration. Need to work closely with your GI if having other symptoms. ...Read more

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Can I take librax a week before sibo testing? Prescribed for IBS because I get cramps but I am also chronically constipated can I take amitiza (lubiprostone) too?

Can I take librax a week before sibo testing? Prescribed for IBS because I get cramps but I am also chronically constipated can I take amitiza (lubiprostone) too?

Librax (clinidium and chlordiazepoxide) ok: Taking Librax (clinidium and chlordiazepoxide) (chlordiazepoxide) should not cause problems with tests of your small bowel function. ...Read more

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