Doctor insights on:
Low Urinary Copper Excretion
Possibly: High urinary copper excretion is most often associated with Wilson's disease, a hereditary disorder of copper metabolism. Other causes such as chronic liver disease may cause this. Further testing is indicated. Please follow up with your physician. Thanks for trusting HealthTap! ...Read more
Why would a doctor insist on a liver biopsy for someone with elevated urinary copper even though a fibroscan came back normal??
Confirmation, stage: Abnormal blood levels of copper/ceruloplasmin?. Liver biopsy confirms Wilson's disease, extent of damage to liver, help in prognosis, detailing a baseline for effects of treatment. Fibroscan is most accurate at the "extremes" (normal vs cirrhosis), but much less accurate in the middle. Likewise, it may show fibrosis (reversible scarring), but does not give information re: stage of inflammation ...Read more
Ceruloplasmin is .14 and urinary copper is high. patient is experiencing tremors, brain fog, hyperglycemia, neuropathy, would could be ?
Copper reference lev: 0-2 months: 0.40-1.40 mcg/ml 3-6 months: 0.40-1.60 mcg/ml 7-9 months: 0.40-1.70 mcg/ml 10-12 months: 0.80-1.70 mcg/ml 13 months-10 years: 0.80-1.80 mcg/ml > or =11 years: 0.75-1.45 mcg/ml cus - clinical: copper, serum - mayo medical laboratories these are in mcg/ml. Need to know 106-what? To interpret yours. www.mayomedicallaboratories.com/test-catalog/clinical+and.../8612?. ...Read more
Stabilized by copper: In this case, the protein that becomes ceruloplasmin (called apoceruloplasmin) is more stable in the presence of copper. So low copper levels will cause a faster degradation of the protein that otherwise becomes ceruloplasmin. Additionally, unlike some proteins, there is no increased production of ceruloplasmin when copper levels are low, . ...Read more
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