Doctor insights on:
Low Urinary Copper Excretion
Possibly: High urinary copper excretion is most often associated with Wilson's disease, a hereditary disorder of copper metabolism. Other causes such as chronic liver disease may cause this. Further testing is indicated. Please follow up with your physician. Thanks for trusting HealthTap! ...Read more
Why would a doctor insist on a liver biopsy for someone with elevated urinary copper even though a fibroscan came back normal??
Confirmation, stage: Abnormal blood levels of copper/ceruloplasmin?. Liver biopsy confirms Wilson's disease, extent of damage to liver, help in prognosis, detailing a baseline for effects of treatment. Fibroscan is most accurate at the "extremes" (normal vs cirrhosis), but much less accurate in the middle. Likewise, it may show fibrosis (reversible scarring), but does not give information re: stage of inflammation ...Read more
Ceruloplasmin is .14 and urinary copper is high. patient is experiencing tremors, brain fog, hyperglycemia, neuropathy, would could be ?
Out of range=12L
How high is this?n Low Ceruloplasmin, is this Wilson disez? coper 76 norm
Not Wilson's: Urine copper is very high in Wilson's. I'm going to assume that your urine copper was 12 mcg/24 hours. You're very right to be concerned about Wilson's -- it's among the most treacherous of all diagnoses. Reference ranges are set so that a few percent of healthies fall outside on either end. In Wilson's, your urinary copper is often 1000's. Best wishes. ...Read more
I have Low caeruloplamin 0.19g/L and low serum copper 12.5 umol/L - units (Australian). Do I have Wilson Disease? or Copper deficiency? Thanks.
Finish workup: If there is any concern at all that you have Wilson's, get a proper screen -- urinary copper and perhaps a genetic screen if you've got suggestive symptoms. Missing Wilson's leads to one of the most grisly deaths possible. Managing it is easy. Your ceruloplasmin is trivially low and reference ranges are set so that a few percent of healthies are outside on either end. ...Read moreSee 1 more doctor answer
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