low platelet high mpv

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Dr. Martin Morell answered:

What is the diagnosis for low white blood cells, low platelets, high mpv, and fatigue?

Could

Blood
be from pancytopenia, certain vitamin deficiencies, myelodysplasia, lupus among others.
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Dr. Kevin Passer answered:

What could low platelet count with high mpv mean in someone with an eating disorder involving severe restricting?

Bad things

Open-uri20130110-17422-17wcdor
It can mean that the body is not functioning properly, in that the bone marrow is being suppressed and the normal way in which blood cells and platelets are manufactured is being disturbed. There may be other detectable and non-detectable changes as well. It's part of malnutrition and the harm to the body. Eating Disorders are DEADLY, with up to a 25% mortality rate in untreated cases.!
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Dr. Ed Friedlander answered:

Mean platelet volume 5.9 which is low. Hematocrit 45.2 slightly elevated. All other test within normal range. Any cause for concern??

No

Hematocrit
But I am concerned that you infarcted some of your spleen, especially as a young woman. Please try to find out why -- and if it was atherosclerosis, do everything you can to keep this at bay.
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Dr. Ed Friedlander answered:

Mean platelet volume .7-.9 points low for 7 years... platelets vary from high to high end of normal.... should i be concerned?

No

Platelet
If this is the only finding, and your physician is not concerned, I'd ignore it. Some people have smallish platelets. I trust you're not iron deficient. Best wishes.
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Had my complete blood count test, find Mean Platelet Volume High - 11.4fl and Hydroxyvitamin D Low - 22.90ng/ml. Please advice reasons and remedy. ?

Follow up

Blood_count
Follow up with your doctor about increase platelet count,if need your doctor can refer you to hematologist for further evaluation.As far as vit,.D level,normal is 30--100, your level is 22.9, i am sure your doctor does recommend vit D3 supplementaion.Just follow their instruction,recheck after 3 months or so.
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I have an arteriovenous malformation (prefrontal cortex). Now, also really low mean platelet volume. Is the AVM's bleeding risk high because of this?

Platelets

Platelet
A low MPV in and of itself is not necessarily a risk factor for bleeding if the total platelet count is normal. If treating the AVM is not an option, then do avoid aspirin and ginkgo biloba, which can both increase bleeding tendency. Speak to your doctor about getting an Ivy bleeding time test, as it will tell you how well your platelets are working. And do make sure your BP is not elevated.
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Reasons why mean platelet volume are low?

Just means

Platelet
the average size of the platelets are small. May not mean anything
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Dr. H Prasad answered:

What does it mean if I have low RBC, WBC, Mean Platelet Volume, Monocyte ABS, and Neutrophil. I have had a fever for the last 2 months;?

Low counts

Fever
sounds like you have low blood counts and fever. could be infection need to see a doctor and have more tests
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Dr. Ed Friedlander answered:

I'm a 37m. I have a constant high bilirubin (~2.1mg/dl), and for several years, high MPV (~13.4fl), and low platelets(140-160k). What does this mean?

Probably nothing

Bilirubin
I'm going to assume you are not taking any medications that will raise your bilirubin, and do not have a mild birth defect causing hemolysis. You probably have Gilbert's non-disease. Your physician knows the workup, which is simple -- if you turn a bit more yellow if you skip a few meals, you're basically got the diagnosis. I would not be worried about the platelets, but monitor them.
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