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Doctor insights on: Low Cortisol Caused By Pituitary Failure

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Can elevated testosterone levels from PCOS cause secondary erythrocytosis?

Can elevated testosterone levels from PCOS cause secondary erythrocytosis?

Unlikely: I have never heard of high testosterone levels associated with PCOS causing erythrocytosis. Receiving testosterone (typically by injection) can do this, but you need very high testosterone levels. ...Read more

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Can a cardiac dilatation be caused by Adrenal insufficiency? because i have very very low basal cortisol levels.

Can a cardiac dilatation be caused by Adrenal insufficiency?  because i have very very low basal cortisol levels.

No: And low basal cortisol levels do not diagnose adrenal insufficiency. You need a cortrosyn stimulation test. We treat dilated cardiomyopathy with aldosterone (produced by your adrenal gland) antagonists. ...Read more

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If high cortisol can decrease serotonin levels then can low cortisol(like due to iatrogenic adrenal suppression) increase serotonin levels?

If high cortisol can decrease serotonin levels then can low cortisol(like due to iatrogenic adrenal suppression) increase serotonin levels?

That: Is a tricky one because there is not enough evidence of low cortisol causing low levels of serotonin. Depression, chronic and severe, is associated with low serotonin and could lower cortisol levels. ...Read more

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Would acth and cortisol be low or high with adrenal insufficiency?

Cortisol: Would be low. Acth would be high if it were an adrenal cause; low if it was a pituitary cause. ...Read more

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Can spironolactone cause low DHEA leading to adrenal insufficiency?

Can spironolactone cause low DHEA leading to adrenal insufficiency?

No: Spironolactone blocks some of the effects of "androgens" (including DHEA). It could potentially lower the levels of some of the androgens, but it will not lower cortisol and cause adrenal insufficiency. ...Read more

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Low dhea are caused by what?

Low dhea are caused by what?

Uncertain at most: If levels of dhea decline with age, can replacing the hormone reverse aging in humans? Nobody knows for sure. In studies, laboratory animals given dhea supplements live up to 50 percent longer than normal. But we humans metabolize dhea differently than animals, so these results don't necessarily apply to us. http://www.anti-agingmd.com/dhea.html#top. ...Read more

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Stress can increase tsh, but how high cortisol causes low TSH where as stress causes high cortisol production.?

Stress can increase tsh, but how high cortisol causes low TSH where as stress causes high cortisol production.?

Cortisol: This is a very complex system. In very basic terms cortisol is produced in response to stress and feeds back inhibiting production of itself (inhibiting crh and acth). Cortisol also inhibits TSH production (as well as growth hormone, estrogen, testosterone and lh production). Thus limiting the response to stress. It is though in chronic stress this feedback mechanism breaks down. ...Read more

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Can menopause be predicted by low hormone levels?

Can menopause be predicted by low hormone levels?

Yes and no: Menopause will happen. The diagnosis is made when Estradiol levels are below 40 and follicle stimulating hormone levels are above 40. However, most women have ovarian dysfunction starting around age 35 which leads to low levels and imbalances of estrogen and progesterone. Symptoms may be present for 15-20 years prior to the onset of ovarian failure (i.e. Menopause). ...Read more

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Can adrenal fatigue cause low grade fever? Are progesterone and estrogen levels related to adrenalin and cortisol?

Can adrenal fatigue cause low grade fever? Are progesterone and estrogen levels related to adrenalin and cortisol?

Dubious diagnosis: "adrenal fatigue" is a pop diagnosis, not an evidence-based one. Since true addison[s isn't a febrile illness, this isn't either. I've wondered if the "subclinical addison's" claims might have something to them, but would urge you not to self-diagnose. The danger of self-diagnosis / treatment is missing another real emotional, situational or physical problem. Your doctor should work your temp up. ...Read more

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Is secondary hypogonadism caused by anorexia reversible?

Is secondary hypogonadism caused by anorexia reversible?

Hypogonadism: About 50% of women who lose their regular cycles due to excess stress, exercise or an eating disorder when weight is regained. If your serum leptin level is low, it is a good sign that this could be a factor. If the LH and FSH levels are low, most physicians will check an MRI to insure that your absent periods are in fact due to the anorexia. ...Read more

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Is high blood Calcium caused by Metestatic Breast Cancer Reversable?

Is high blood Calcium caused by Metestatic Breast Cancer Reversable?

Yes: Osteolysis and hypercalcemia not uncommon in metastatic breast Ca to bone. It is primarily mediated by osteoclast not a direct effect of tumor cells but by factors that stimulate osteoclast production and action. Breast Ca cells in bone also express parathyroid-related protein (PTHrP). Locally produced PTHrP causes osteolysis that can be ameliorated by administration of anti-PTH mAbs and chemo ...Read more

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Would a very high prolactin level (no pituitary tumour) cause hypothyroidism or does hypothyroidism cause high prolactin levels?

Would a very high prolactin level (no pituitary tumour) cause hypothyroidism or does hypothyroidism cause high prolactin levels?

See below: Thyrotropine releasing hormone (trh) from hypothalamus stimulate prolactin and thyroid stimulating hormone (TSH) in anterior pituitary hormones. If you have problems on both, pls see an endocrinologist or neuroto check for pituitary tests . Good luck. ...Read more

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Relationship between high testosterone levels in a male and possible adrenal tumor? Other symptoms of adrenal tumor aside from testosterone levels?

Relationship between high testosterone levels in a male and possible adrenal tumor? Other symptoms of adrenal tumor aside from testosterone levels?

Doubt any: High testosterone levels in a normally-functioning young man probably mean nothing, perhaps a personal variant in the amount of the binding protein. I am most concerned about your pituitary adenoma, which as a prolactin-producer is likely to affect your libido independent of your testosterone levels. Adrenal tumors can produce other androgens but seldom testosterone. ...Read more

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43 yo f, afternoon cortisol high, cortisol suppression test high, CT of adrenal glands normal. Other causes of elevated cortisol?

43 yo f, afternoon cortisol high, cortisol suppression test high, CT of adrenal glands normal. Other causes of elevated cortisol?

Pituitary : Cortisol is under control of the pituitary. You need to know if the source is coming from the pituitary. We call this Cushing disease. See a specialist to work this up. Cushing's is one of the most difficult diagnosis to make, even for a specialist. ...Read more

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Can this be hypopituitairism: high cortisol, highish prolactin, low HGH, lowish TSH, low LH and FSH in luteal phase, (lowish in follicular), low ADH (vasopressin)?

Can this be hypopituitairism: high cortisol, highish prolactin, low HGH, lowish TSH, low LH and FSH in luteal phase, (lowish in follicular), low ADH (vasopressin)?

Pituitary: It is difficult to diagnose hypopituitarism vased on labs you provided. High cortisol goes against hypopituitarism. High prolactin can lower FSH and LH.. TSH normal range is 0.3-4.. If pituitary dysfunction is suspected , we check Free T4, not TSH.. I hope this answers your question ...Read more

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How to know either it's from adrenal or pituitary gland that cause my hypocortisolism MRI pituitary normal. Acth level low.H/o exogenous steroid 2010.

How to know either it's from adrenal or pituitary gland that cause my hypocortisolism MRI pituitary normal. Acth level low.H/o exogenous steroid 2010.

Stimulate adrenals: Have your doctor do an adrenal stimulation test to check your adrenal response. Acth levels are often inaccurate and frequently not diagnostic. If you're on cortisone replacement already, it doesn't make much difference what the cause is, however your pituitary function can be analyzed one hormone at a time. Check w/an endocrinologist. ...Read more