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Doctor insights on: Low Aldosterone Treatment

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Aldosterone was 2 ng/dL (fasted, early morning, upright) is this normal or low? Does it warrant further testing? Cortisol was high/normal 22.2 mcg/dL

Aldosterone was 2 ng/dL (fasted, early morning, upright) is this normal or low? Does it warrant further testing? Cortisol was high/normal 22.2 mcg/dL

More history: I don't know much about your history or what has caused you to have this testing in the first place so I won't be of much help, BUT the aldosterone level is low and may warrant further testing for Cushing's syndrome, 17-alpha-hydroxylase deficiency,Liddle's syndrome,ectopic ACTH syndrome, or mutations of your mineralcorticoid receptors. You need to talk to your doctor for more direction. ...Read more

Dr. Narina Baburyan
372 doctors shared insights

Aldosterone (Definition)

Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer section (zona glomerulosa) of the adrenal cortex in the adrenal gland. It is involved in blood pressure regulation, potassium ...Read more


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High pregnenolone levels and low aldosterone levels, is this a bad hormone problem?

High pregnenolone levels and low aldosterone levels, is this a bad hormone problem?

Could be: Could be a sign of congenital adrenal hyperplasia with one of several enzyme defects. This is rare. Depends on who's ordering the test. If endocrinology, this is the reason. Adrenal fatigue is a popular diagnosis now but really represents metabolic stress and is a reaction of the system to stress. The answer is not to address the symptom of the stress but to address the stress itself. ...Read more

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If someone was to have low angiotensin II and low aldosterone would you expect to see a lower renin also?

If someone was to have low angiotensin II and low aldosterone would you expect to see a lower renin also?

Renin levels: If one has a low aldosterone and angiotensin ii, one would expect a high renin level. Renin leads to angiotensin i and ii synthesis. If those levels are low and the person is ambulatory, the person's renin would be expected to be high. For a diagram of the renin-angiotensin-aldosterone system go to this link; http://www.Google.Com/search?Hl=en;site=imghp;tbm=isch;source=hp;biw=2556;bih=1234;q=renin+angiotensin+system;oq=+angiotensin+sy;gs_l=img.1.1.0j0i5l9.576.4679.0.9029.16.9.0.5.5.0.227.974.0j5j1.6.0....0...1ac.1.35.Img..5.11.985.Luxw_l48srm#fa. ...Read more

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Should all hypoaldosteronism patients have edema /can a person have low aldosterone without this symptom/?

Should all hypoaldosteronism patients have edema /can a person have low aldosterone without this symptom/?

Hypoaldo & edema: It would be rare for a person with a low aldosterone to have edema. But would depend on kidney function, cause of low aldo and salt intake. If you have had both kidneys removed which causes low aldo then you will get edema related to how much salt you eat. if your aldo is low because u eat way to much salt you might have edema. If no adrenals is causing low aldo then rare to have edema ...Read more

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My hormone tests came in with high 3α-Androstanediol, high aldrosterone, high aldosterone, high 5a-THB, elevated 5α-reductase, and low 11b-hydroxyetiocholanolone. What can this mean?

My hormone tests came in with high 3α-Androstanediol, high aldrosterone, high aldosterone, high 5a-THB, elevated 5α-reductase, and low 11b-hydroxyetiocholanolone. What can this mean?

Tests steroid metab: Apparently you are undergoing a work up for steroid and male hormones/androgen metabolism. These are unusual blood tests, and typically only performed when, usually a specialist, has a specific diagnosis in mind. I'm certain you can receive a better, more satisfying explanation by working with the doctor who ordered these tests. Pursuing that is your best option. Good wishes:) ...Read more

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Is an a.m. Aldosterone of 6ng/dl on the low side? Range is < or = 28 which seems dumb because a value of 0 or 1 would be "in range".

No: That is an acceptable level in and of itself, but it must be evaluated in the context of other hormonal levels and other symptoms and signs you are experiencing. ...Read more

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How can a person have normal Sodium while he have low aldosterone and testosterone at the same time ??

Easy: Physiology is deeper than we can explain at the undergraduate level. Water follows sodium and the body does everything it can to protect its osmolarity. You don't simply pee out all your sodium even if you tend to lose because you're on an aldosterone blocker, taking a diuretic, or whatever. Be thankful for this. ...Read more

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Is it true that many people with adrenal fatigue also have low aldosterone?

Is it true that many people with adrenal fatigue also have low aldosterone?

No: Patient with adrenal insufficiency, not fatigue, can have low aldosterone. It's easy to check. All you need is a blood test. ...Read more

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Aldosterone 161 pmol/l - renin/aldosterone ratio 5 - renin 11.4 ng/l - angiotensin II 8ng/l. I have postural orthostatic tachycarda. Why low angioten?

All connected: I am not an expert on this and you don't mention your lab standards so it is hard to say, but they are all connected to each other to regulate the volume of fluid and salt held or released by your kidney and there for your blood pressure. Too little salt then too little volume of blood and BP drops when you stand. ...Read more

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In what circumstances will aldosterone be secreted over ADH (vasopressin) and vice versa. Are they both secreted in response to low BP? What about low plasma osm?

In what circumstances will aldosterone be secreted over ADH (vasopressin) and vice versa. Are they both secreted in response to low BP? What about low plasma osm?

Good questions!: Aldosterone release is regulated by renin. I believe hypotension (or rather long-standing hypoperfusion) may be a trigger, especially in secondary aldosteronism (due to CHF, for example) ADH (vasopressin), (vasopressin) on the other hand, is triggered by hyperosmolarity, rather than hypotension. Low osmolarity will, of course, suppress ADH (vasopressin). ...Read more

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How can a hyposecretion of aldosterone and cortisol hormones lead to low blood sugar?

Gluconeogenesis: Hi. In prolonged fasting, cortisol plays an important role in a process the liver uses to make sugar from amino acids called gluconeogenesis. If glycogen (stored sugar) is depleted (happens in less than 24 hours of fasting), and the body cannot make enough new sugar from amino acids, low blood sugar can occur. Aldosterone does not play a role in gluconeogenesis. ...Read more

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Without having an instantaneous blood draw, how can one know for sure if their near-death experiences are from adrenal emergencies? (Dangerously low cortisol and aldosterone)?

Without having an instantaneous blood draw, how can one know for sure if their near-death experiences are from adrenal emergencies?  (Dangerously low cortisol and aldosterone)?

Near death: If you are talking about near death experiences like seeing 'the light' or dead loved ones, I am unaware of anyone proving a mechanism for this. ...Read more

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Male 22 angiotensin II was 8ng/l and aldosterone 161 pmol/l i urinate a lot and have pots. Could this cause low blood volume?

Male 22 angiotensin II was 8ng/l and aldosterone 161 pmol/l i urinate a lot and have pots. Could this cause low blood volume?

Can't answer: Normal values vary from lab to lab. This question is complex and can't be answered in a vacuum. ...Read more

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Low aldosterone ~3, normal renin and cortisol. Which type of adrenal issue and remedy available? Finding out reason for hyperkalemia and low hco3

Low aldosterone ~3, normal renin and cortisol.  Which type of adrenal issue and remedy available? Finding out reason for hyperkalemia and low hco3

Hypoaldosteronism: You may have normoreninemic hypoaldosteronism. It can be treated by a daily dose of fludrocortisone, under a physicians care. Could be due to medications or primary adrenal gland failure (zona glomerulosa). Additional tests could confirm this. ...Read more

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Low aldosterone ~3, normal renin. Low Na, co2, high k. Creatinine 1.4-2.2 in same week.Can type 4 RTA cause this fluctuation in ckd? Neph endo no help

Type 4 RTA: If anyone can figure it out it should be a nephrologist. What did he, she or it say? There are many causes of Type 4 RTA and will need to ask a number of questions to help get to the cause. 1. Meds u r on? 2. were u on meds when renin and aldo were measured. 3.What did 24 hr urine at the same time show? 4. Other medical illnesses. Happy to have you consult directly with me. ...Read more

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Conflicting info on diuretics use in ckd4 with hyperkalemia issues (low aldosterone) with 2 g proteinuria. Will 20 mg lasix (furosemide) daily dose harm kidney?

Conflicting info on diuretics use in ckd4 with hyperkalemia issues (low aldosterone) with 2 g proteinuria. Will 20 mg lasix (furosemide)  daily dose harm kidney?

Follow MD advice : You already have kidney problems and should be monitored by a kidney specialist. Follow their advice closely rather then trying to treat yourself. What is appropriate for your problem is best determined by some who does this for a living then try to make sense of all the information that you get from your well meaning friends and the internet ...Read more

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Low aldosterone ~3, normal renin. Low Na, co2, high k in blood. Creatinine 1.4-2.2 in same week.Can type 4 RTA cause this fluctuation in diabetic ckd?

Creat fluctuates: Many things cause Cr to go up or down. So need to answer these questions. 1.What meds r u taking? 2. Any imaging procedure with contrast? 3. recent dehydration? 4 recent illness" and many more. When you had gotten all this together consult with me and can probably help figure out what is going on. ...Read more

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If someone had low angiotensin ii, low aldosterone and low vasopressin. Took florinef (fludrocortisone) would it retain water even though low vasopressin?

Yes: Florinef (fludrocortisone) is a mineralocorticoid. It works in a way similar to aldosterone to increase salt and water retention by the kidneys. It does not rely on angiotensin, vasopressin, or aldosterone for its action. ...Read more

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I pee a lot of what i drink low normal aldosterone low angiotensin ii. Will florinef (fludrocortisone) help me retain more and pee less?

Think about this:: If you urinate just 10 cc more than you take as food or drink per day, in 1 year, you'll be 3.6 liters drier and in 5 years, 20 liters behind! (not possible). No, your kidneys carefully balance your fluids. What low aldosterone and angiotensin control is your BP and your sodium ; potassium. Flurinef will raise your BP and help you retain sodium and excrete potassium. ...Read more

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Blood co2 low ~15 on arb with low aldosterone. Neph prescribed sodium bicarb but cardiologist does not recommend. High phos, k. Is calcium bicarb ok?

Blood co2 low ~15 on arb with low aldosterone. Neph prescribed sodium bicarb but cardiologist does not recommend.  High phos, k. Is calcium bicarb ok?

Details, details: You can't really expect someone to recommend how to treat you by looking at a few numbers. You have to sit down with a doc face-to-face with whatever info you have and discuss your situation with him/her. This is not to be done in 400 spaces. You noted that 2 doc's you spoke to had differing opinions! What is that telling you! ...Read more

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Kidney function worsens on benicar (olmesartan) 20 mg (scr 1.6 to 2.6 in a month) but proteinuria improves. No stenosis in us. Need MRA? Low aldosterone, ok renin.

Kidney function worsens on benicar (olmesartan) 20 mg (scr 1.6 to 2.6 in a month) but proteinuria improves. No stenosis in us. Need MRA? Low aldosterone, ok renin.

Depending ...: What and how the evaluation should be done for individuals should be based on the conclusion of detailed history, physical exam, and preliminary testing. As to yours, which one you need can be deduced by your treating doctor & consultants. Elevating creatinine suggests some impairing blood perfusion through kidneys by fluid contraction + already marginal renal function. More? Ask your doctors... ...Read more

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My aldosterone was < 1.0 ng/dl is this low? Being checked for tiredness, hair falling out, acne, weight gain. She is checking all of my hormones

My aldosterone was < 1.0 ng/dl is this low? Being checked for tiredness, hair falling out, acne, weight gain. She is checking all of my hormones

Low: Normal values for aldosterone in adults are 5 to 80 ng/dl when standing or sitting and 3 to 16 when lying down. Acne and weight gain are more commonly seen with Cushings Disease, but sounds as if your doctor is on track to find the your cause of your tiredness. ...Read more

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Low Aldosterone 10 range 15-70 with normal sodium and potassium?? and I eat a normal sodium diet, not too much and not too little sodium..

ACTH challenge tes: A low aldosterone could be due to a problem with the adrenal glands or due to other causes. An ACTH stimulation test for aldosterone can be done - a low aldosterone response to the stimulation would indicate that there is dysfunction in the adrenal glands. A high aldosterone response would indicate that the problem is not due to adrenal gland dysfunction. ...Read more