Doctor insights on:
Lovenox Enoxaparin Heparin
What are the risks in taking lovenox (enoxaparin) /heparin during pregnancy? What if baby aspirin is taken as well?
Heparin: Plain Heparin and Lovenox (enoxaparin) (lmw heparin) can both cause easy bruising and bleeding, even hemorrhage, decrease in normal platelet numbers, bone thinning - scary stuff - but usually are very safe. The trick is never to use them without a clear benefit to outweigh the risks, and always monitored under a specialist care. ...Read more
Lovenox (enoxaparin) vs. heparin: Unfractionated Heparin (UFH) & enoxaparin (lovenox or lmwh) both prevent blood clots by indirectly inhibiting the function of 2 important clotting factors, xa and iia (thrombin). Ufh is very large , while lmwh is smaller. Dosing of UFH is IV or sq every 8-12 hrs, and lmwh sq every 12-24 hrs. Care is needed with lmwh if renal failure. Ufh is more likely to cause hit, a dangerous allergic reaction. ...Read more
Discuss with doctor: Not sure what a&c means. Mthfr mutation is very weakly associated with miscarriage. If you are heterozygous then blood thinning medicines are not indicated. If you are homozygous then possibly. Ask about a fasting homocystine test. Your age of 41 is also a risk factor for miscarriage. ...Read moreSee 1 more doctor answer
For pregnancy for someone with history of uedvt...What is diff b/w heparin and lovenox (enoxaparin)? Why would one also be on baby aspirin?
Heparins, etc: Unfractionated Heparin (UFH) can be given IV or sq (as prophylaxis) and was used historically and is used now especially if want to turn on/off and be able to reverse it (w/ protamine). Enoxaparin (lovenox) is a low molecular weight Heparin (lmwh) that can be given subcutaneously (sq) for prophylaxis or treatment. Aspirin is used more to prevent arterial (mi, tia, stroke) not venous clots. ...Read more
Yes, you can: Unfractionated Heparin and low molecular weight Heparin are safe and useful drugs during pregnancy for women with increased risk for having blood clots. A history of having a blood clot or a strong family history of a blood clot associated with a familial thrombophila disorder are indicators for the prophylactic use of heparins. These agents can be used throughout pregnancy, but if low molecular weight heparins are used, a switch to unfractionated Heparin is required if epidural anesthesia is considered for labor and delivery, because of risk of epidural hematoma if low molecular weight Heparin was used within 24 hours before delivery. Since onset of labor is unpredictable, most obstetricians will make the switch at 36 weeks gestation. A discussion with your obstetrician before pregnancy or early in pregnancy about management with Heparin should help alleviate concerns you have about its use. ...Read moreSee 2 more doctor answers
Lovenox (enoxaparin) & bones: Yes, long-term use of Lovenox (enoxaparin) over many months is known to cause bone loss. If this is a concern, a different anticoagulant shot known as Arixtra can be considered. Additionally, there are new oral anticoagulants such as xarelto that can be considered as well. ...Read more
Tendency to clot: Factor v leiden is a hereditary abnormality of a clotting protein that increases your risk of forming clots, notably in the veins (phlebitis). If you are undergoing a procedure that would also increase this risk (surgery, prolonged immobilization), Lovenox (enoxaparin) might be used preventively. It is only for short-term use, and oral drugs such as warfarin would be used if you need long-term protection. ...Read more
Do: you mean at the site of subcutaneous injection? if yes then it could be normal. iIf not then it is abnormal. Could be minimized by ice application and changing sites off injection? if infected may need I&D or antibiotics ...Read more
Factor 5: Factor 5 leiden deficiency is a inherited condition that increase risk for bleeding. Often these patients need bloodthinners lifelong. ...Read more