Doctor insights on:
Lou Gehrig Disease
Unfortunately no : At this time, we do not possess effective treatment to stop or reverse classical motor neuron disease (als), and perhaps the best we can do is delay tracheostomy with riluzole. The disease ultimately causes death in spite of careful and thorough care. We have found some patterns involving superoxide dismutase, but no breakthroughs yet. ...Read more
Paralysis of muscles: Lou gehrig's disease is also known as amyotrophic lateral sclerosis. The disease attacks nerve cells in the brain and spinal cord that run the muscles that we can normally control. The cause of the disease is not known. In about 10% it is genetic. People with lou gehrig's disease slowly become weak in the arms and legs, and can have difficulty speaking, swallowing, and breathing. ...Read moreSee 1 more doctor answer
ALS: Amyotrophic lateral sclerosis or lou gehrig's disease is a degeneration of upper and lower motor neurons. The symptoms include weakness of the upper arms and legs. Often the muscles will appear to move under the skin like a bunch of worms. The diagnosis is made with an EMG, a lumbar puncture and an MRI of the brain and spinal cord. An opinion from a neurologist will provide you further information ...Read moreSee 2 more doctor answers
No: Als is relatively rare, with 90% sporadic and 10% genetic (25% of which have mutations involving copper/zinc superoxide dismutase). There is no specific or successful treatment to date, and no known approach to prevent the disease even if one is a member of a family at risk. ...Read moreSee 2 more doctor answers
Most are sporadic: While most cases of lou gehrigs disease do not have a known cause ("sporadic als"), approximately 5% of cases do run in families ("familial als"). There have been many proposed risk factors for developing sporadic als, but no clear smoking gun has been found to date. ...Read moreSee 1 more doctor answer
Neither: 90-90% of case of ALS are not inherited, it occurs at random at its cause is not known. In 5-10% of cases there is a familial form of the disease. In these 5-10% of cases it is usually dominant (meaning it is only necessary to have one copy of the defective gene) remember however most of the time it is not inherited at all. ...Read moreSee 1 more doctor answer
Not close: We have learned that some cases are associated with fronto-temporal dementias rarely, and some cases cluster in certain areas of the world. We do know that it is a disorder of "misfolded proteins" (superoxide dismutase), but we only have palliative meds and approaches. Lastly, ALS was thot to cause lou gehrig's demise, but this is being reassessed. ...Read more
Symptom treatment: A tracheotomy may be used to access the airway for suctioning and ventilation as a person with ALS gets weaker and needs help with respiration and secretion removal. This treatment itself just helps manage symptoms of the disease but does not do anything in regards to curing the disease itself. ...Read more
NOT fully clear: We do know it is a disease which results in loss of motor nerve cells in brain and spinal cord, and there is an incidence of 10% familial involvement. Rarely, there is a mutation in gene encoding of copper/zinc superoxide dismutase, but otherwise, we are not clear as to what is causing this devastating condition. ...Read moreSee 1 more doctor answer
GORK: It is unpredictable of how fast ALS (lou gehrig disease) will end up in death. It depends on the person, its presenting symptoms, the velocity of progression, institution of treatment etc. There's only one medication approved for that by far called riluzol. In most cases, though, it progresses to significant disability in a matter of 2-3 years. ...Read moreSee 1 more doctor answer
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