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Doctor insights on: Losec Proton Pump Inhibitor

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Is pantoprazole as good as Nexium (esomeprazole) or losec?

Is pantoprazole as good as Nexium (esomeprazole) or losec?

Yes, but...: A review in Journal of the American Pharmacists Association(Eval of Omeprazole,Lansoprazole,Pantoprazole,&Rabeprazole in Treatment of Acid-Related Diseases,J Am Pharm Assoc. 2000;40(1)),there is no difference amongst the proton pump inhibitors(pantoprazole, omeprazole, esomeprazole, rabeprazole). Clinically, we find some people respond better to one than another; if one doesn't work, try another. ...Read more

Dr. Tri Huynh
824 doctors shared insights

Omeprazole (Definition)

Omeprazole is the generic equivalent of prilosec, the first oral acid-reducer agent of the proton pump inhibitor ...Read more


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What are the effects of proton pump inhibitors used long term? prescription omeprazole, 40mgm sig 1 cap daily

Malabsorption: The major concern with long-term use is poor absorption of nutrients such as magnesium and many vitamins. Stomach is there for a purpose - it helps in the digestive process. I'd suggest at least annual monitoring by your doctor with blood tests. ...Read more

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Hello doctors. Can GERD eventually stop responding to proton pump inhibitors like omeprazole?

Hello doctors. Can GERD eventually stop responding to proton pump inhibitors like omeprazole?

Yes and No: Remember the goal in medicine and in health is to not just 'treat' GERD forever, but to find the cause of it and to eliminate the cause so that treatment for the long term is unnecessary. Many in the U.S. fail to do this and continue their very dangerous habits causing GERD and think it safe to take PPI's for the long term. This is erroneous thinking and dangerous for health. ...Read more

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Is calmepan contraindicated with proton pump inhibitor?

No problem: These two medications should have no significant interactions. ...Read more

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Can you get bad side effects taking proton pump inhibitor (ppi) tablets?

Can you get bad side effects taking proton pump inhibitor (ppi) tablets?

PPI side effects: There are concerns that reducing stomach acidity may be contributing to clostridium difficile-associated diarrhea. There also may be a link between long-term use of ppis & osteoporosis. If you develop resistant diarrhea or are at risk for osteoporosis, consult your fp for further evaluation. ...Read more

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What are the differences between a proton-pump inhibitor and a h2-antagonist?

Proton pump: Ever heard of wikipedia>\? Great resource. The work ind different ways and not enough room here to give you all the details. ...Read more

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Can there any long term side effects of using proton pump inhibitor medicines for say a period of 20 days?

Can there any long term side effects of using proton pump inhibitor medicines for say a period of 20 days?

Antacids & Long Use: The biggest problem of long term antacid use is that the cause of the acid problem is often not sought. Also long term acid can be a cause of a very dangerous esophageal cancer and can represent other serious illnesses. Thus it is always best to be using these medications in conjunction with good health care and good testing and monitoring. ...Read more

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Is it safe to take a proton pump inhibitor like tecta, for a long time? I am 24 yrs old and have been taking ppis for 6 years now?

Is it safe to take a proton pump inhibitor like tecta, for a long time? I am 24 yrs old and have been taking ppis for 6 years now?

Proton pump blocker: The long term use of ppi have been linked to poor calcium absorption, increased risk if intestinal infections in older people etc. Most of these side effects have been noted in people using ppi twice daily for several years. It is usually advisable to limit long term use of ppi if at all it is possible like switching to every other day if that will control your symptoms. ...Read more

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Can using proton pump inhibitor medicines for 20 days cause any damage?

Can using proton pump inhibitor medicines for 20 days cause any damage?

Probably not, but...: Usually not, but we don't know you nor your entire medical history so this would be a question to ask the doctor who suggested you take the medication. In general, ppi's are well tolerated and safe in otherwise healthy people without major medical problems, and who don't take any medications that have an interaction with the ppi. Hope that helps. ...Read more

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Can you take an over-the-counter proton pump inhibitor continuously for gerd?

Same as prescription: You need to see your doc to figure out what you have, why you need to be on such a med, if other less potent meds will work as well, or if they are needed at all. In general, the lowest dose, of the least potent medicine, for the shortest period of time to do the job is a good approach. You can't figure that out without your doc. ...Read more

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I'm a med. Rep. And i would like to ask you , what is - in your opinion- the best proton pump inhibitor molecule ? That will help me doing my job :)

I'm a med. Rep. And i would like to ask you , what is - in your opinion- the best proton pump inhibitor molecule ?  That will help me doing my job :)

Comparative studies: Studies comparing 3 or more drugs, head to head, are what you are looking for. Seems like drug companies are not doing those studies, so we don't really know which drugs are better. A doctor's favorite drug may be the one that has been in use longest, the one he has had years of experience with, or the one that is available to his patients (on formulary). Demand the company do comparative studies. ...Read more

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Can mild acalculous gb wall thickening with fatty liver be managed by proton pump inhibitor medicines?

Can mild acalculous gb wall thickening with fatty liver be managed by proton pump inhibitor medicines?

Fatty liver: Managing both fatty liver and gallbladder disease means low fat diet. Fatty liver can be reversed if treated, and low fat diet with weight loss helps. Proton pump inhibitor will decrease acid stomach. Be well. ...Read more

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Does taking a proton pump inhibitor like Nexium (esomeprazole) (40 mg day) greatly reduce the chance of bleeding from taking asprin daily?

Does taking a proton pump inhibitor like Nexium (esomeprazole) (40 mg day) greatly reduce the chance of bleeding from taking asprin daily?

Yes: initial studies showed pretty good effects.those were in people taking a LOT of aspirin like drugs. in people taking daily aspirin.... http://www.ncbi.nlm.nih.gov/pubmed/24326741 maybe drugs like aspirin work 100% of the time ?!? looked really good.......... ...Read more

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What are proton pump inhibitors ? Does any food product act as proton pump inhibitor? What foods to avoid when I want to avoid PPI? I have vitiligo.

What are proton pump inhibitors ?
Does any food product act as proton pump inhibitor?
What foods to avoid when I want to avoid PPI?
I have vitiligo.

Hydrogen ion: The stomach's proton pumps start to pump out hydrogen ion to form hydrochloric acid when you eat. If a PP inhibitor is present in the blood, it will shut down the PP when they start to activate. There is no natural way to inhibit the PP although dietary modifications (avoiding tea, coffee , acidic foods, fatty foods, spicy foods) may reduce your symptoms. Vitiligo has nothing to do with it. ...Read more

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Which proton-pump inhibitor is best? Nexium, (esomeprazole) Prilosec, or Prevacid and why?

Which proton-pump inhibitor is best? Nexium, (esomeprazole) Prilosec, or Prevacid and why?

Each has relative...: ...merits based on duration of action, side effects, tolerance, cost/insurance coverage. All are equally efficacious, so your question should be better phrased, "which is better for me?", and that we can't answer since we don't know your particular circumstances. ...Read more

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Do you have to stop taking a proton pump inhibitor like Prilosec two weeks before a h. Pylori biopsy?

H. Pylori: In general u are not asked to stop ppi for h. Pylori biopsy. Ppi can suppress h pylori in the antrum of the stomach but it may migrate to the body. Biopsies should be taken from the body of the stomach too. ...Read more

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How can the therapeutic effects of antacid drugs, h2 blockers, proton pump inhibitor drugs, misoprostol?

How can the therapeutic effects of antacid drugs, h2 blockers, proton pump inhibitor drugs, misoprostol?

Question?: I'm not sure I fully understand what your question is? The drugs you listed all help with symptoms of GERD or stomach ulcers, and they have different means by which they help patients with these problems. The safest and easiest to take are antacids and H2 blockers. Please consider rephrasing your question more specifically. ...Read more

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I take a proton pump inhibitor for acid reflux, but have bad breath despite excellent oral hygiene. If my ppi is to blame, what can I do?

I take a proton pump inhibitor for acid reflux, but have bad breath despite excellent oral hygiene. If my ppi is to blame, what can I do?

Maybe LERD?: Likely lerd with sourbrash. Stomach acid & pepsin will result in inflammation of the vocal cords and oral cavity (with acid regurgitation) = lerd. Acute laryngitis may result, but watch out for chronic hoarseness, throat clearing, hallitosis, airway spasms, cough, bronchitis, an asthma-type presentation, & even a higher risk of throat cancer. Maybe you need a stronger acid reducer? See doc. ...Read more

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I am using voltaren (diclofenac) 75mg. And proton pump inhibitor for my stomach. How long should I wait to take voltaren (diclofenac) after i take the inhibitor?

I am using voltaren (diclofenac) 75mg. And proton pump inhibitor for my stomach. How long should I wait to take voltaren (diclofenac) after i take the inhibitor?

PPI + NSAID: For GI prophylaxis, ppi is preferably taken on empty stomach first thing in morning or at least 30 minutes prior to eating/drinking. Voltaren (diclofenac) can then be taken with meal. May need twice daily ppi dosing if underlying gerd/gastritis or symptoms of NSAID induced GI irritation. 2nd dose is preferably taken 2 hours after last meal. Rx pills that contain combination nsaid/ppi can be taken w/ food. ...Read more

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Medical Records state, GASTROINTESTINAL PROPHYLAXIS W/PROTON PUMP INHIBITOR & DEEP VEIN THROMBOSIS PROPHYLAXIS W/SEQUENTIAL COMPRESSION DEVICE. What does that mean?

Medical Records state, GASTROINTESTINAL PROPHYLAXIS W/PROTON PUMP INHIBITOR & DEEP VEIN THROMBOSIS PROPHYLAXIS W/SEQUENTIAL COMPRESSION DEVICE. What does that mean?

Precaution care: It sounds like these are precautions taken to prevent surgical or hospitalization (bedrest) complications due to inactivity and not eating. Stomach acid is reduced with proton pump inhibitor meds and deep vein thrombosis caused by venous stasis prevented with a device that wraps around the calves and squeezes intermittently. ...Read more

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Is it okay to combine h2 blockers like Zantac (ranitidine) with proton pump inhibitors (ppi)?

Is it okay to combine h2 blockers like Zantac (ranitidine) with proton pump inhibitors (ppi)?

Sure, best at night: Some ppi's don't last all day, so acid production rises by evening. Such patients may benefit from either a second dose of ppi medication before dinner, a switch to a longer acting ppi, or the addition of h2 blocker medication at bedtime. ...Read more

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Are there any safer alternatives to proton pump inhibitors (PPI) for treating GERD / Acid reflux? I'm concerned about the long term side effects

Are there any safer alternatives to proton pump inhibitors (PPI) for treating GERD / Acid reflux?  I'm concerned about the long term side effects

PPIs. : All medications have the potential to cause side effects, which I understand is disconcerting. However, the PPIs are a very effective class of medication for GERD, so the benefit should be considered with respect to the potential for risk. ...Read more

Dr. Linda Callaghan
498 doctors shared insights

Losec (Definition)

Losec is a proton pump inhibitor which is a kind of ...Read more


Dr. Sanjiv Kaul
291 doctors shared insights

Proton Pump Inhibitor (Definition)

Proton pump inhibitors are a kind of ...Read more