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Doctor insights on: Long Term Imitrex

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Are there risks associated with taking Imitrex (sumatriptan) for migraines on a long term basis, for 1-2 migraines per month?

Are there risks associated with taking Imitrex (sumatriptan) for migraines on a long term basis, for 1-2 migraines per month?

None that we know of: So long as the long term usage remains at 1-2x/month. If at some point the patient or doctor recognizes that things are escalating to 2-3/month or 3-4/month...even though these are still below what would be considered CHRONIC patterns of dependency it should be clear that something is changing that needs to be dealt with...otherwise, long term use @ 1-2x/month is fine. BTW, you should start DIARY ...Read more

Dr. Jennifer White
208 doctors shared insights

Sumatriptan (Definition)

Sumatriptan is a synthetic drug belonging to the triptan class, used for the treatment of migraine headaches. Structurally, it is an analog of the naturally occurring neuro-active alkaloids dimethyltryptamine (dmt), bufotenine, and 5-methoxy-dimethyltryptamine, with an n-methyl sulfonamidomethyl- group at position c-5 ...Read more


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I get migraine headaches 5x/week and take Imitrex (sumatriptan) for it. Are there short / long term risks?

I get migraine headaches 5x/week and take Imitrex (sumatriptan) for it.  Are there short / long term risks?

OVER USING IMITREX (sumatriptan): Serious side effects include heart arrhythmia (irregular heart beat)/palpitation, and rare heart attack especially older folks with risks. Being male at 61, it is a bit risky. Using 5x/wk is excessive. There are daily meds to help prevent migraine attacks and so i suggest consulting doc for eval and treatment. Since you are taking med 5x/wk for severe headaches, why not daily to stop it? Good luck. ...Read more

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How long does Imitrex (sumatriptan) last?

How long does Imitrex (sumatriptan) last?

Long enough: The effect of immitrex should be several houirs, long enough to resolve a headache. It can be given as a second dose in 2-4 hours. It should be given with a non steroidal antiinflammmatory such as Ibuprofen or naprosyn, (naproxen) to supplement its effect and speed relief. ...Read more

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I've been suffering with migraines for almost a decade, taking up to 9 imitrex per month. About two weeks ago, I stopped the Imitrex and started eliminating dietary triggers. Yet, I'm still having migraines. How long should I expect to be in pain while "d

Migraines: This is very disabling. While you try to do a life-style changes this may not help. Have you tried nerve blocks - which even if thy work for short durations you may be a candidate for possible PNS to control the headaches. ...Read more

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Imitrex (sumatriptan) side effects how long do they last commonly? And can taking Imitrex (sumatriptan) cause toxic neuropathy?

Imitrex (sumatriptan) side effects how long do they last commonly? And can taking Imitrex (sumatriptan) cause toxic neuropathy?

Imitrex (sumatriptan) side effects: The side effects of imitrex, (sumatriptan) which are normally changes in heart rate, dizziness, or sleepiness, normally last less than one day. Imitrex should not cause neuropathy. If you have neuropathy, there is probably some other cause. ...Read more

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Breastfeeding and Imitrex (sumatriptan) for migraine safe? If not, how long will it stay in my breastmilk after taking?

Breastfeeding and Imitrex (sumatriptan) for migraine safe? If not, how long will it stay in my breastmilk after taking?

No info available: Sumatriptan (imitrex) is excreted into human breast milk. Caution is advised when considering the administration of sumatriptan to a nursing woman. The american academy of pediatrics has no position on the use of sumatriptan during breast-feeding. Infant exposure to sumatriptan can be minimized by avoiding breastfeeding for twelve hours after treatment with sumatriptan. (by the fda website). ...Read more

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Is frova (frovatriptan) used to treat menstrual migraines? My neurologist says it lasts longer than Imitrex so it should help. Do you agree?

Is frova (frovatriptan) used to treat menstrual migraines? My neurologist says it lasts longer than Imitrex so it should help. Do you agree?

Migraine: Of the triptans, Frova (frovatriptan) and Amerge (naratriptan) have a the longest half life. They have been associated with lesser incidence of a headache relapse after an initial good response. It is ideal for catamenial migraines if menses are periodic and predictable. Some report successful treatment when the medications are taken daily for 4-5 days at menstral onset or a day before onset. ...Read more

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Was advised by neurologist to take hydrocodone if Imitrex (sumatriptan) didn't work. Can that help w migraine pain?  after 100 mg Imitrex (sumatriptan) how long till nxt pill?

Yes, it can, but...: Hydrocodones is a codeine/narcotic derivatives which can relieve any pain for several hours. If used too frequently in some people who are addictive-prone, that is major problem. Presuming neurologist worked up for causes of migraine, the treatment depends on the severity and the frequency. If they occur every month, rx should try a med to prevent them entirely. Max dose over 24 hrs = 100 mg more. ...Read more

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History of headaches/migraines, but none this long. This was a migraine for a day and still mild headache for over 1 week. On verapamil & imitrex. Can't take nsaids. Avoiding tylenol (acetaminophen) so doubt rebound.

History of headaches/migraines, but none this long. This was a migraine for a day and still mild headache for over 1 week. On verapamil & imitrex. Can't take nsaids. Avoiding tylenol (acetaminophen) so doubt rebound.

Chronic daily HA's: Could be your headache pattern has altered, and with this frequency, do not even try to use imitrex, (sumatriptan) it will not work, and may make things worse. Verapamil is a mediocre preventative for such headaches and is not approved by the fda. First see your doc, and get evaluated. You might break up pattern with steroids, depakote, topirimate, or otc's but get some guidance. ...Read more

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Can one build a tolerance to imitrex (sumatriptan)? 

In a way: There does seem to be a waxing and waning effect of many headache medications, and a drug that works well for years can become less effective with time. In addition, using Imitrex (sumatriptan) more than 2-3 times per week can lead to the development of a medication overuse headache, which is very difficult to effectively treat. You may wish to consider adding a prophylactic medication. ...Read more

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Imitrex (Definition)

Sumatriptan is an anti-migrane agent which is a kind of ...Read more