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Doctor insights on: Long Term Effects Zoloft

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Dr. Donald Jacobson
1,041 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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Are there any long term side effects for zoloft (sertraline)? Like months after taking it?

Are there any long term side effects for zoloft (sertraline)? Like months after taking it?

Yes, but...: Two common longer term side effects are: 1) sexual [difficulty having an orgasm, reduced sex drive, difficulty having an erection] and 2) weight gain [although weight gain on zoloft (sertraline) is less than another similar antidepressant like paroxetine]. All this being said, there are approaches to minimize side effects that you should speak with your doctor about. Hope this answer helps. ...Read more

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What are the short term and long term effects of consuming alcohol while on 200mg of Zoloft (sertraline)? Is 4 to 5 drinks only once in awhile okay?

Not ok.: Zoloft (sertraline) and alcohol should not be mixed per the drug manufacturer. Zoloft (sertraline) may enhance the effect of alcohol. The combination may impact both motor skills and depressive symptoms. Drinking four to five drinks in a sitting is not considered moderation. ...Read more

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What is the max amt of time one should take Zoloft and buspar (buspirone)?What are the long term effects of taking these.

What is the max amt of time one should take Zoloft and buspar (buspirone)?What are the long term effects of taking these.

As long as necessary: In conjunction with the prescribing physician you should take these medications as long as is necessary to successful treat the condition for which they are prescribed. There are no significant long term adverse effects. ...Read more

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I've been taking Adderall for 10 years (30 mg 2xday). What are the long-term effects of central nervous system stimulants?#nqlu i'm 57 & in addition to adderall, take Zoloft (50 mg), Armour Thyroid (90 mg), bystolic (10 mg), and tamoxifen (20 mg).

I've been taking Adderall for 10 years (30 mg 2xday). What are the long-term effects of central nervous system stimulants?#nqlu i'm 57 & in addition to adderall, take Zoloft (50 mg), Armour Thyroid (90 mg), bystolic (10 mg), and tamoxifen (20 mg).

Usually not many: Some doctors recommend having "holidays" from stimulants, for times when not having the best concentration and focus might not matter as much - like weekends, vacations etc. There is little or no evidence that long-term medicinal stimulants taken as prescribed cause any significant damage to the cns, although sleep disturbance/anxiety and hopelessness (depression) may be related. Talk to your doc. ...Read more

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Where can I find the long term effects of sertraline drug esp in patients that have been taking it since teens (long meaning >7yr)?

Where can I find the long term effects of sertraline drug esp in patients that have been taking it since teens (long meaning >7yr)?

Nat Library of Med: Doing a literature search in the national library of medicine shows the adverse events reported with sertraline were most likely to occur early in the course of treatment and there was no evidence of any increase in events in the elderly or with longer-term treatment. Sertraline was not associated with excess of death from any cause, suicides, suicide attempts or serious life-threatening events. ...Read more

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I'm currently taking 300 mg of Zoloft (sertraline) and my dr. may move up to 400. Are there long term side effects for these doses?

Drug dosing: Zoloft (sertraline) more than 200mg/day is not the usually recommended dose, but individuals vary in their requirements. It is also recommended if you not responding with one medication, instead of keep increasing the dose which may cause more side effects. Changing to different agent or adding another group of medicine might help ...Read more

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How does increased ambient heat affect side effects of long term psychotropic drugs like zoloft (sertraline)?

Doesn't matter: Long term use of medications shouldn't be affected by ambient temperature unless you're referring to its storage in which case usually cool dark cabinet should be fine. Ambient temperature is more a matter of comfort. What's warm for you might be cool for someone else. But temperature shouldn't affect effectiveness nor side effect profile of medications. ...Read more

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What are the consequences in the short & long term..... If i used "zoloft 50mg" for 1 month for my anxiety and then i decided to give up ?

What are the consequences in the short & long term..... If i used "zoloft 50mg" for 1 month for my anxiety and then i decided to give up ?

Zoloft (sertraline) consequences: There are no direct consequences from having taken zoloft (sertraline) for one month. However, what concerns me is that i believe that would be a mistake to not try either a different medication or getting into psychotherapy, yoga, acupuncture, meditation, neural feedback, or any of the other modalities that are capable of treating anxiety. Chronic anxiety is a miserable experience. Take it from one who's been there. ...Read more

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Dr. Alan Ali
993 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more