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Doctor insights on: Long Term Effects Of Zofran

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Are there any long term negative effects from taking too much zofran (ondansetron)?

Are there any long term negative effects from taking too much zofran (ondansetron)?

Many drug: Interactions -any h/x liver disease, minimal dosing. Not meant as a long duration medication to my knowledge. ...Read more

Dr. James Henning
425 doctors shared insights

Ondansetron (Definition)

Ondansetron is a nausea and vomiting agent which is a ...Read more


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What're the effects of long term Zofran (ondansetron) use for treating chronic nausea caused by anxiety? Been taking abt 3, 4mg pills per week for 1.5 years already

What're the effects of long term Zofran (ondansetron) use for treating chronic nausea caused by anxiety? Been taking abt 3, 4mg pills per week for 1.5 years already

Hi. I'm not aware of: Significant problems reducing and then eliminating Zofran (ondansetron) from your regemen. I would suggest to have an alternative plan to treat the nausea, when it comes. Start tapering by reducing your daily dose in half. Let us know how it goes. Shabbat Shalom. ...Read more

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Is it dangerous to take Zofran (ondansetron) for long periods of time?

Zofran (ondansetron): This depends on how you define a long time and what the dose is. The maximum dose was reduced a couple of years ago because of potential cardiac side effects. Nausea is generally a symptom of something else. If you are a chemotherapy patient, zofran (ondansetron) is fine. Otherwise, check with your physician as to why you are needing zofran (ondansetron). ...Read more

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Took 6mg sumatriptan injection. How long to wait till I can take 8mg Zofran (ondansetron) pill so the meds won't interact?

Took 6mg sumatriptan injection. How long to wait till I can take 8mg Zofran (ondansetron) pill so the meds won't interact?

Whenever: To my knowledge those teo medications won't interact so you don't have to wait. also, if you are needing triptans for headache then you may benefit from taking a med every day to prevent the headache. Butterbur is an over the counter supplement that can prevent migraines. Several safe meds are also effective. ...Read more

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Started feeling nausea like I was gonna a vomit out of nowhere. Took 8mg Zofran 20min ago how long till it works? Haven't vomited yet but nauseous.HELP

Started feeling nausea like I was gonna a vomit out of nowhere. Took 8mg Zofran 20min ago how long till it works? Haven't vomited yet but nauseous.HELP

Depends on why: Nausea and vomiting in a 20yo female can result from something as simple as an emotional reaction to very serious but rare emergency conditions. If it comes with diarrhea it's usually food poisoning or a virus. Without diarrhea could be pregnancy, a UTI*, or other pelvic problem. If there is abdominal or pelvic pain or fever, go to the ER. If your body has good reason to vomit, Zofran won't stop it. ...Read more

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How long does Buspar (buspirone) 5 mg 3xs day stay in your system. My last does was last night i only took for 6 days. My dr said to stop. when can I take zofran

How long does Buspar (buspirone) 5 mg 3xs day stay in your system. My last does was last night i only took for 6 days. My dr said to stop. when can I take zofran

Buspar/clearance: Under ordinary circumstances, the Buspirone should clear in 12-24 hrs, although traces could be detected in urine (if we could test). I don't believe there would be any interference if you are or not on Zofran (ondansetron). ...Read more

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I take Zofran (ondansetron) off for bouts of nausea but it takes too long to work, can Zofran (ondansetron) for injection be prescribed or is it just for hospital use?

I take Zofran (ondansetron) off for bouts of nausea but it takes too long to work, can Zofran (ondansetron) for injection be prescribed or is it just for hospital use?

Prescription only...: Prescription only but the bigger question is why you are having so much nausea. Ask your doctor if your medications could be contributing to this problem. Nausea is listed as a side effect of all three of your medications! ...Read more

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Is Zofran (ondansetron) 4mg safe if you have a healthy heart? How long after stopping the drug (I took one dose) does the risk for cardiac issues cease?

Ondansetron: Zofran (ondansetron) in doses greater than 16 mg at a time has been implicated in prolonging the qt interval. This effect would last for a few hours while the drug was in the system. A single 4 mg dose does not carry this risk. ...Read more

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How long does a typical 4mg pill of Zofran (ondansetron) take to start working on nausea due to gastroenteritis. Taken at the onset of symptoms, before any vomiting?

How long does a typical 4mg pill of Zofran (ondansetron) take to start working on nausea due to gastroenteritis. Taken at the onset of symptoms, before any vomiting?

Typically....: It usually begins to start relieving nausea within 30-60 minutes. Hopefully, you will get relief and not begin vomitting. If it doesn't help and/or your symptoms worsen, get back in touch with your doctor. Good luck!! ...Read more

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Esrd pt was just discharged from long hospital stay, receiving high dose dilaudid & Zofran (ondansetron) which were d/c'd abruptly. Now acute wd sx. Help w/ mgmt?

See Previous Answer: You basically have three options: resume opiates and taper gradually to minimize withdrawal. Use subutex (buprenorphine) as a replacement opiate which has less withdrawal issues. Use meds which block withdrawal symptoms like clonidine. The problem with the last option is that it can drastidcally lower your BP which might make your dialysis management difficult. ...Read more

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Does taking Zofran (ondansetron) make stomach virus last longer?

More's not better: Zofran (ondansetron) may slow the transit time in the gut and rarely the bowels can stop moving. Therefore, potential to prolong the period in wh/a virus is in contact w/the gut. In a study in children w/vomiting gastroenteritis who took zofran (ondansetron) x 48 hrs, return to the er w/diarrhea was higher in the kids w/zofran (ondansetron). Another study gave 1 dose & the er return was less w/zofran (ondansetron) but kids had more diarrhea. ...Read more

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Curious how long after swallowing a Zofran 4mg or 8mg pill does it have the effect of vomit prevention if taken at the onset of nausea caused by IBS?

Curious how long after swallowing a Zofran 4mg or 8mg pill does it have the effect of vomit prevention if taken at the onset of nausea caused by IBS?

That: Depends upon whether you have an empty stomach! A full or partially filled stomach will delay the absorbtion of the medication...otherwise 30 minutes should start the pill's effect(s)
Hope this helps!
Dr Z ...Read more

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Taking ketorolac, oxy/acetaminophen, flomax, (tamsulosin) zofran to manage kidney stone. No bm for 48 hours. Is this too long? What can I do to have a bm?

Taking ketorolac, oxy/acetaminophen, flomax, (tamsulosin) zofran to manage kidney stone. No bm for 48 hours. Is this too long? What can I do to have a bm?

Suppositories: YOu can get some glycerin suppositories to help bm. the constipation is from the oxycodone. If you will need it longer start on some bisacodyl and take as instructed on bottle. I would not worry about not having a BM is 48 hours. This is not unusual in the case of narcotics.
Best wishes ...Read more

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Think I'm coming down w stomach bug, have explosive diarrhea, severe nausea, foul smelling gas. Took 8mg Zofran pill 20min ago. How long till it works???

Think I'm coming down w stomach bug, have explosive diarrhea, severe nausea, foul smelling gas. Took 8mg Zofran pill 20min ago. How long till it works???

Nausea, Diarrhea !: Zofran tablet works for Nausea and vomits in half hour!
Nausea/Diarrhea usually is from Gastroenteritis Staph aureus exotoxin from Sandwiches that have become hot and spoiled!
Norovirus gives nausea and vomits, occasional diarrhea from exposure to it in cruise ships! ...Read more

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Can a one time dose of iv zofran cause side effects after 14 hours?

Can a one time dose of iv zofran cause side effects after 14 hours?

Zofran: Pharmacological studies on Zofran show that patients with moderate to severe hepatic impairment (liver) may have an extended half-life of Zofran. In most patients over half the drug is gone in 5.7 hours. Older patients may take longer to clear Zofran as well. It really depends on what side effects you are talking about as well.
https://tinyurl.com/yc9bvu99 ...Read more

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I left Zofran pills in the foil wrapping, inside the box in my bag in the car for 2days. Car wasn't extremely hot but def hotter than should be.effects?

I left Zofran pills in the foil wrapping, inside the box in my bag in the car for 2days. Car wasn't extremely hot but def hotter than should be.effects?

Well : If Madison stay around room temperatures they're generally fine if they get a little warmer they can get weaker if they get too hot they can become ineffective. If they're too hot they degrade and are not effective at all ...Read more

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Is it okay to take a Zofran (ondansetron) after taking Adderall or are there adverse effects?

Is it okay to take a Zofran (ondansetron) after taking Adderall or are there adverse effects?

Most likely OK: It doesn't appear, from searching a database, that are any significant drug-drug interactions between those two medications. ...Read more

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Can an anti-nausea medication be added to my i.v. sedation line? Such as Zofran (ondansetron) to prevent the effects of the anesthesia?

Can an anti-nausea medication be added to my i.v. sedation line? Such as Zofran (ondansetron) to prevent the effects of the anesthesia?

Discuss with anesthe: Siologist. This is their call. Based on your discussion they'll determine best what to use to make your procedure as comfortable as possible. ...Read more

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Is it possible to get Zofran (ondansetron) otc?

Prescription item: And, although advertisements for the purchase of this drug without a prescription are plentiful on the internet, caution is strongly advised. It's best to obtain a proper prescription. ...Read more

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Can you take exlax with zofran?

Absolutely.: Zofran is for nausea.
Exlax is to treat constipation.

They do not interact with each other, so unless you have an allergy or intolerance to one or both medicines, they should be fine to take together. Feel better! ...Read more

Dr. Dariush Saghafi
331 doctors shared insights

Zofran (Definition)

Zofran is a nausea and vomiting agent which is a ...Read more