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Doctor insights on: Long Term Effects Of Synthroid

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How long after getting proper dose of synthroid (thyroxine) should I begin to feel less symptomatic? Last tsh was 23.

How long after getting proper dose of synthroid (thyroxine) should I begin to feel less symptomatic? Last tsh was 23.

Usually on the order: Of two to three weeks. But I should warn you there are some patients that some neuromuscular and psychiatric symptoms can take months to resolve. It's also possible that some symptoms thought to be related to hypothroidism like fatigue or weight, may in fact be related to other factors/issues, even when the hypothyroidism is corrected. ...Read more

Dr. David Sneid
1,420 Doctors shared insights

Thyroxine (Definition)

Thyroxine is a thyroid agent. ...Read more


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What are the long term effects of synthroid (thyroxine)? I've read about connections to cancer.

What are the long term effects of synthroid (thyroxine)? I've read about connections to cancer.

No connection: With cancer. People with a history of thyroid cancer often take synthroid (thyroxine) for the rest of their lives. Synthroid (thyroxine) is T-4 a form of thyroid hormone! ...Read more

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If our on-demand delivery of drugs like Synthroid (thyroxine) were interrupted by economic collapse, what could I do to acquire my med? Can I stock it long term?

If our on-demand delivery of drugs like Synthroid (thyroxine) were interrupted by economic collapse, what could I do to acquire my med? Can I stock it long term?

Don't worry: ' be a bull not a a bear ' will not going to a economic collapse, if it happens unfortunately we have to worry more issues than availability of synthroid (thyroxine), ii you want you can stock, but no need for it. ...Read more

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After long term Synthroid (thyroxine) over dose of 200mcg for 5 years how long will it be till I feel better? Lowered to 175 cancer suppression.

After long term Synthroid (thyroxine) over dose of 200mcg for 5 years how long will it be till I feel better? Lowered to 175 cancer suppression.

patience required: With history of cancer (? Thyroid you did not mention), TSH stimulates not only thyroid cell also cancer cell, (tsh levels 0.3 to 3) need to know your age and weight, status of tumor to calculate the dose, 200 mcg I don't think is over dose, always needs adjustment, you may have associated diseases, speak to your doctor will make you better with other medication good luck. ...Read more

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Can asgwaghanda be taken long term? Me thyroid dr told me 2 stop taking levoxyl (thyroxine) because my body is producing enough. He knows I take this herb

Can asgwaghanda be taken long term? Me thyroid dr told me 2 stop taking levoxyl (thyroxine) because my body is producing enough. He knows I take this herb

There is no: Scientific information to confirm ANY benefits to taking asgwaghanda. There is no way to confirm that your thyroid levels would be normal without replacement if the lab tests were drawn while you were receiving replacement. The only way to tell for sure is to be totally off replacement for at least six weeks before lab is drawn. ...Read more

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My 4 year old took 8 of my 200mcg synthroid (thyroxine). The p.A.-c said it would not bother him. But I am still worried. Is there instant side effects or longer?

My 4 year old took 8 of my 200mcg synthroid (thyroxine). The p.A.-c said it would not bother him. But I am still worried. Is there instant side effects or longer?

Overdose: Call poison control right now. They will calculate how much he got according to his weight and they will tell you what you need to do and what symptoms he/she may have. Any time your child takes medications not prescribed for him/her always call poison control right away. The number should be in the front of your phone book. ...Read more

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Just started on synthroid (thyroxine) (finally!!!) how long before symptoms improve (cold intolerance, brittle nails, hair falling out, constipation? What side effects should I watch for or expect? How long before dose increase?

Just started on synthroid (thyroxine) (finally!!!) how long before symptoms improve (cold intolerance, brittle nails, hair falling out, constipation? What side effects should I watch for or expect? How long before dose increase?

I usually advise: My thyroid patients that it may be SEVERAl WEEKS for them to notice a "difference" and THAT is when I re-check the tests at 2 weeks to begin with!
The "cold intolerance " is usually the first to "respond"
BE PATIENT!!! It may take several visits before your problem is "sorted out" Hope this helps!

Dr Z ...Read more

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Synthroid (thyroxine) withdrawal lasts for how long?

It depends on how lo: It depends on how long and how much dose you have been on synthroid (thyroxine).It can take few days to few weeks. ...Read more

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How long does thyroxine stay in your system? Thank you!

How long does thyroxine stay in your system? Thank you!

Weeks: Half-life elimination is 6–7 days for euthyroid patients; 9–10 days for hypothyroid patients; 3–4 days for hyperthyroid patients. That means that 1/2 of the drug hormone/medication still remains in the person 6-7 days after stopping the medication. The medication Levothyroxine is chemically the same as the naturally produced hormone thyroxine by the thyroid gland. ...Read more

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Can it take longer for Synthroid (thyroxine) to work vs. Levothroid?

No: They should work in the same time frame. However, it is always good when switching brands of l-thyroxine to recheck thyroid hormone levels about 6 weeks afterwards, to make sure you are stable on the new brand. ...Read more

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How long does it take for the increase in Synthroid (thyroxine) dosage to take effect?

Weeks: You may start to feel a difference in 1-2 weeks, but you need to give a new dosage 6 weeks before rechecking thyroid blood levels. ...Read more

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What will happen if I stop taking thyroxine and how long before I start seeing the side affects?

What will happen if I stop taking thyroxine and how long before I start seeing the side affects?

Less than a week: Depending on how underactive you are will determine how soon you will feel the effects of not taking your thyroid medication. It may be a week or it may be a month. It also depends upon how sensitive you are and how in tune you are to your body. ...Read more

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I've been w/o my Synthroid (thyroxine) for 6 mos now, I was taking 100mcg daily. How long do I have before symptoms get really bad and if so what will happen?

Now: This is too long. See your physician now, and have your TSH and free T4 checked now. It they are normal, then you no longer have hypothyroidism. But if they are abnormal, you need to restart your meds to prevent long term complications. ...Read more

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I've been w/o my Synthroid (thyroxine) for 6mos now, I was taking 100mcg daily. How long do I have before it really starts to affect me and how serious can it be?

I've been w/o my Synthroid (thyroxine) for 6mos now, I was taking 100mcg daily. How long do I have before it really starts to affect me and how serious can it be?

Should be already: The 1/2 life of synthroid (thyroxine) is approx. 30 days. That's why we check your TSH and ft4 levels 4-6 weeks after making adjustments. So the synthroid (thyroxine) is well it of your system by now. How serious will depend on how far hypo you will go and how sensitive you ate to the symptoms. Generally won't cause lasting damage, but you will feel awful. ...Read more

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Does it take longer for Synthroid (thyroxine) to work vs. Levothyroid?

Not really: Absorption of each thyroid preparation is a little different, and you should not switch brands, if possible. But both synthroid (thyroxine) and Levothroid are long acting hormones, with a half-life of 1 week. I doubt you would notice a difference with regards to onset of action, for example if you were starting to take them for hypothyroidism. ...Read more

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How long after a thyroidectomy should one wait before beginning synthroid (thyroxine)?

How long after a thyroidectomy should one wait before beginning synthroid (thyroxine)?

Need path results.: Start it ASAP after surgery, as long as you won't have post-op radioiodine therapy (RAI) used for some thyroid cancers-- in which case start AFTER RAI.

Usually you don't know if you need RAI for sure until final pathology results come in about a week post-op. Some surgeons start Synthroid (thyroxine) right after surgery and stop if path determines need for RAI. Others will wait for path first, then ...Read more

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How long can you live without thyroxine after a thyroidectomy? How long does it take to become unwell?

How long can you live without thyroxine after a thyroidectomy? How long does it take to become unwell?

Hypothyroidism: That is complex. A baby born without a thyroid can have life long severe consequences if treatment is delayed or discontinued. An elderly or compromised person might die because their body can't withstand the additional problem of hypothyroidism. If it is you, otherwise healthy, thyroid was removed you might go a while feeling hypothyroid before you were severely ill. Monitor! Take medicine! ...Read more

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Is it okay to skip my Synthroid (thyroxine) medication? I am waiting for a refill and it is taking a long time.

Yes, but: Missing a couple days should be ok but symptoms of hypothroidism will slowly return if you don't restart your meds. ...Read more

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If I take Synthroid (thyroxine) first thing in the morning, how long do I have to wait before I take Propranolol?

If I take Synthroid (thyroxine) first thing in the morning, how long do I have to wait before I take Propranolol?

I tell my patients: Thy need not wait: I think other MD's make too big a deal of separating these meds. Take them & see what your lab tests show. HRS, MD, FACC www. Thepmc. Org ...Read more

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Hypo - took 25mcg Synthroid (thyroxine) for 4wk. Tests show hyper. No meds 3wks- still hyper. How long after no meds will it take for ft3 and ft4 levels to drop?

Hypo - took 25mcg Synthroid (thyroxine) for 4wk. Tests show hyper. No meds 3wks- still hyper. How long after no meds will it take for ft3 and ft4 levels to drop?

Complicated.: There are many explanations for this. Ft3 and ft4 levels are difficult to measure and interpret - some have argued that it should be called a ft4 estimate. T3 (liothyronine) levels drop in a few days and T4 levels in about two weeks. I wonder if your first TSH was possibly a lab error? ...Read more

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Total thyroidectomy more than a year ago due to hashimotos disease. How long could I live without taking my thyroxine 150mcg?

Total thyroidectomy more than a year ago due to hashimotos disease. How long could I live without taking my thyroxine 150mcg?

Does not add up: Hashimoto is not a reason for thyroidectomy. Why would you not not take replacement medication? You may live for a variable length of time but would not be healthy. Stay on the medication and do not change the dose without consulting your doctor. ...Read more

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How long does Synthroid (thyroxine) dosage change take to work? I'm 13w pregnant & just found out it's way too low so I'm worried I'll misscarry.

How long does Synthroid (thyroxine) dosage change take to work? I'm 13w pregnant & just found out it's way too low so I'm worried I'll misscarry.

Thyroid: No need to worry. Your doctor needs to keep an eye on you as you proceed through pregnancy, changing the dose as needed. You and baby will be fine. Your obstetrician will look after you as well. ...Read more

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Just diagnosed with hypothyroidism and on day 2 of l-thyroxine. How long does it typically take to for medicine to improve symptoms?

Just diagnosed with hypothyroidism and on day 2 of l-thyroxine. How long does it typically take to for medicine to improve symptoms?

Weeks: Hi. Depending on how significantly hypothyroid you were at time of diagnosis, it can take 2-3 weeks for you to begin to feel the effect, and a few months for it to normalize symptoms (on the right dose). If your hypothyroidism was caught early, you may not notice any change. Symptoms are not specific for any disease. After 6-8 weeks, your doc will probably check your TSH and free T4 to assess dose ...Read more

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How long after getting proper dose of synthroid (thyroxine) should I begin to feel less symptomatic? Last tsh was 23.

Usually on the order: Of two to three weeks. But I should warn you there are some patients that some neuromuscular and psychiatric symptoms can take months to resolve. It's also possible that some symptoms thought to be related to hypothroidism like fatigue or weight, may in fact be related to other factors/issues, even when the hypothyroidism is corrected. ...Read more

Dr. Joseph Mathews
615 Doctors shared insights

Synthroid (Definition)

Synthroid is a thyroid agent. ...Read more