Doctor insights on:
Long Term Effects Of Sinemet
Years of use: Turmeric has been used traditionally for a very long time as a food coloring and spice, and for a number of disorders, it us used medicinally and preventatively in some cultures. Long term: possible indigestion, nausea, diarrhea, may cause liver problems, might cause ulcers if you take too much. It can also increase bleeding, so don't use before surgery. It may interact with a number of meds. ...Read more
Effexor (venlafaxine): Effexor (venlafaxine) is used to treat depression and anxiety. The most common are headaches, high blood pressure, chest pain, blureed vision and withdrawals if tapered off too quickly. The best advice is to call your doctor for medical advice about side effects, if concerned. ...Read more
Many: Short term- weight loss, tooth enamel erosion from stomach acid, esophageal ulcers, nuitritional and electrolyte imbalances and skipped periods. Long term- no menses, cardiac irregular heartbeats that could result in cardiac arrest and death and, kidney failure from severe dehydration. ...Read more
Not much to report : Am a psychiatrist and am also a boarded sleep medicine specialist. I have been in my current practice for 21 years. I worry more about ambien, (zolpidem) because of the number of people I have seen develop amnesia on it. I have never seen anyone develop amnesia on temazepam, even at 60 mg doses. 20% of my psych patients have sleep apnea, so I am vigilant about sleeping issues in my practice. I don't think that anyone is comfortable having people on long-term benzodiazepines. However, many people simply need long-term benzodiazepine management. You do have a lot of years ahead of you. Since we really don't know the long-term liability of benzodiazepine use on the memory, it is always best whenever possible to convert to something that might be less of concern. Trazodone comes to mind as a potentially good option. Seroquel is a good sleep drug but it carries more liability long-term then temazepam. Discuss other options with your psychiatrist please. ...Read moreSee 2 more doctor answers
Positive Effects: Abilify (aripiprazole) is a second generation antipsychotic medication indicated for several mental conditions including, schizophrenia, bipolar disorder, and major depressive disorder. Long term effects include positive outcomes for person with these disorders. Abilify (aripiprazole) can also cause tardive dyskinesa, neuroleptic malignant syndrome, weight gain, type two diabetes, and elevation of one's triglycerides. ...Read more
NSAID side effects.: Nsaids like Ibuprofen have some unfortunate side effects that make them a poor choice for many people in pain and most people with pain after sports activities. They cause injury to stomach, kidneys, prevent your body from rebuilding cartilage in your joints from every day wear and tear, and stop your body from healing an acute injury like a tendon injury or an ankle sprain. ...Read more
Antidepressants: Although many antidepressants have been around for decades - not all are old. So long-term effects cannot be generalized across the many antidepressants on the market. In addition, most of the data is on those with depression or anxiety disorders, so it may not be generalizable to everyone. Is there a specific drug in question? ...Read more
Nephrotoxicity: Most concerning long-term adverse effect of Program (tacrolimus) is nephrotoxicity (damage to the kidneys). The drug has a narrow therapeutic index and therefore the blood level of the drug is often monitored to avoid side effects. Other known side effects include tremor, elevated blood pressure, elevated blood glucose, and hair loss. ...Read more
Long term side effects of short-term prednisone use? Took 60,60,40,40,20,20,10,10 mg for migraine. Expect any longterm effects?
COMMENTS: A good approach to break up a chronic daily headache pattern. Unlikely to experience any long-term consequences of 8 days of high dose steroids, but if you were to use over several weeks to months, risk rises for osteoporosis, anti-cholinergic effects, glaucoma, cataracts, avascular necrosis of shoulder, hip, or knee, etc. You are at extremely low risk. ...Read moreSee 2 more doctor answers
Addiction, mostly: The major side effects of opioids are constipation (which can be severe), increased sweating, weight gain, edema and hormonal changes, including reduction of testosterone and estrogen levels. These are usually dose related and are rarely seen at low doses, although it is possible. Physical dependency, which almost everyone gets if they take it in reg. Doses long enough, and addiction are issues. ...Read more
What is the typical starting dose of sinemet (carbidopa and levodopa) for a patient with parkinsons? How long do you need to take it feel its effects? Several weeks?
See below: Sinemet® (carbidopa-levodopa) is a combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome.Sinemet® cr (carbidopa-levodopa) is a sustained-release combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome. ...Read moreSee 1 more doctor answer
Sinemet-CR: This has to be determined by careful titration thru your doctor. Initial dose is usually 50-200. Consult your Neurologist. ...Read more
Sinemet (carbidopa and levodopa): Not sure what milligram each, but if that's what your doctor prescribed & your symptoms are under control & you are tolerating the medication well, then you should be ok. ...Read more
Yes: But the GI side effects would make it intolerable. ...Read more
It depends: Because of cost considerations its worth trying it for a while. Watch for peak dose dyskinesis and dose failures or wearing off. ...Read more
Neither: Generic drugs are held to standards where the manufacturer must prove "bioequivalence" to the branded drug. The molecules must be structurally the same, and the same standard of quality and purity must be met. The pills and the packaging themselves may look different, but the active ingredient is the same. It can be thought of as the difference between clorox bleach and safeway brand bleach. ...Read more
Dosages : Dosages are adjusted for the specific needs of each patient - there is no standard dose for any specific time period. Sinemet (carbidopa and levodopa) comes in carbadopa-levodopa doses of 10-100, 25-250, and 25-100. These can be combined and given at various times throughout the day to best relieve the symptoms of parkinson's disease. If you are not sure of your dose or the dose of someone you are caring for, you need to call the doctor that prescribed the medication to clarify. Good luck! ...Read more
On sinemet (carbidopa and levodopa) 2 times per day 62.5. I want off this to try other alternatives first how do I safely do this. I do not agree
with my diagnosis of pd.?
See your doctor: If you can't find any common ground then it's best to part ways and find a physician you feel mors comfortable with. That said, you should negotiate a time period during which you can try alternatives before resuming orthodox therapy. Your doctor will help wean you. ...Read moreSee 1 more doctor answer
When switching from regular Sinemet (carbidopa and levodopa) to CR, do you need to add little more CR to achieve the same dose of the regular Sinemet (carbidopa and levodopa)?
Slowly: Depends on dosing/schedule, but its very important to taper very slowly. It would be best to call your prescribing doctor and have them give you a clear tapering schedule. ...Read more
Parkinson patient for 7 years currently taking sinemet & requip (ropinirole). Only sinemet seems to releive systoms. Is there any risks of stoping requip (ropinirole)?
See neurologist: The Requip (ropinirole) may not be playing much of a role at this point, and could be tapered off over a few days. There really is no substantial withdrawal issue usually, and unlikely to experience any challenges. Discuss with your doctor, and revamp your medications, as dbs will certainly change your med needs. ...Read more
I took ten tylenol (acetaminophen) and then I took sinemet, benztropine, clonazapan, serquel. Will this kill me?
Did you take: multiple pills of each? If you are having thoughts about killing yourself, get seen at the nearest emergency room now. Have a friend or relative drive you or call 911 for emergency services for transport. You can call the National suicide hotlines 24/7 at 1-800-suicide (1-800-784-2433) or 1-800-273 – talk (1-800-273-8255) for support. ...Read more
Before I take Stalevo, (carbidopa and levodopa and entacapone) I'm on but shortly after, I suddenly go off. What's causing this ?
See a physician: Your questions is not very clear, but is important to see your doctor for accurate reason for your symptoms ...Read more
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