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Doctor insights on: Long Term Effects Of Metoclopramide

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How safe is reglan (metoclopramide)? Used for long term gastroparesis.

How safe is reglan (metoclopramide)? Used for long term gastroparesis.

Risky: Maximum recommended duration of Reglan (metoclopramide) use is 12 weeks. It's because of the increases risk with the long term use including extrapyramidal side effects such as tardive dyskinesia, which is an involuntary movement disorder. ...Read more

Reglan (Definition)

Metoclopramide increases emptying of food from the stomach and decreases symptoms of nausea, vomiting, heartburn, and fullness,. It should ideally be taken 30 minutes before meals. It's use in pregnancy should be reserved for severe conditions where the risks to the baby of not treating exceed the potential ...Read more


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My 85 yr.Old grandma has terrible gerd, the only thing that helps is reglan (metoclopramide). But this is not supposed to be used long term. What else can be done?

My 85 yr.Old grandma has terrible gerd, the only thing that helps is reglan (metoclopramide). But this is not supposed to be used long term. What else can be done?

She needs it, use it: Likely any medicine, we recommend using the lowest effective for the shortest duration possible. Some people needs life-long treatment! if she uses and is benefiting from it without causing significant side effects, then it is reasonable to continue. If having side effects, then look for alternative. At her age and doing well, she should have whatever she needs that helps w/o harm. Good luck. ...Read more

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My daughter's told her vargas nerve may be damaged and was prescribed Reglan (metoclopramide). She can't be on it for a long time, what can she do when she goes off it?

My daughter's told her vargas nerve may be damaged and was prescribed Reglan (metoclopramide). She can't be on it for a long time, what can she do when she goes off it?

Concerns: How and why has this information been confirmed? Regian is used for gastrointestinal symptoms, and does not imply abnormality of a major cranial nerve. This seems confusing to me and I believe you need a second opinion. ...Read more

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My daughter is being treated for gastroperisis with Reglan (metoclopramide). It has been about 4 days with minimal change. How long does Reglan (metoclopramide) usually take?

My daughter is being treated for gastroperisis with Reglan (metoclopramide).   It has been about 4 days with minimal change.   How long does Reglan (metoclopramide) usually take?

Reglan (metoclopramide): oral Reglan (metoclopramide) is sometimes useful in the treatment of gastroparesis. Although individual doses begin working immediately, it may take weeks to see the effect in someone who has chronic gastroparesis. If there is no effect, the dosage may need to be adjusted. It is important to watch for side effects while on the medication, in addition. If she is seeing no relief, talk to your doctor. Good luck. ...Read more

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Should I space out Reglan (metoclopramide) from when I take the Percocet? If so, how long?

No: You should be ok taking both together.. Reglan (metoclopramide) and Percocet work via two separate mechanisms. A possible concern is that taking both might cause some constipation or stomach upset, so I'd watch for those symptoms. You should be able to address the constipation with a fiber supplement. ...Read more

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What's the problem with taking Compazine together with Reglan (metoclopramide)? If they can't be taken together, how long after taking Compazine can I take Reglan (metoclopramide)?

What's the problem with taking Compazine together with Reglan (metoclopramide)? If they can't be taken together, how long after taking Compazine can I take Reglan (metoclopramide)?

Severe side effects: Any med has some risk of side effects; when prescribing, we balance benefits against risks. When combining Compazine with Reglan (metoclopramide), (metoclopramide) rare risks of side effects of each are magnified & include confusion, fever, fast heart rate, stiff muscles,& involuntary movements. Recommend asking a pharmacist how long after Compazine it's safe to take Reglan (metoclopramide).Zofran (ondansetron) may be safer choice to ask doc about ...Read more

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How much shud be the dose of Thorazine & Reglan (metoclopramide) to treat hiccups. How long should I be taking them if the hiccups dont stop. Diabetes is controlled.

How much shud be the dose of Thorazine & Reglan (metoclopramide) to treat hiccups. How long should I be taking them if the hiccups dont stop. Diabetes is controlled.

2 to 3 days: Thorazine (chlorpromazine) - 25-50 mg every 6-8hr; if hiccups persist after 2-3 days of oral therapy, see your doctor for possible intramuscular or slow intravenous Thorazine (chlorpromazine). Reglan 10 mg every 6 - 8 hours ...Read more

Dr. Marcus Reidenberg
241 doctors shared insights

Metoclopramide (Definition)

Reglan (metoclopramide) improves GI motility and is also ...Read more