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Doctor insights on: Long Term Effects Of Metformin

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Are there long term effects of diabetes medication (glyburide, metformin)?

Are there long term effects of diabetes medication (glyburide, metformin)?

Not many: Glyburide is a sulfonourea (it forces your pancreas to produce more insulin). Metformin does three things... It helps your Insulin work better by making the Insulin receptors in the body more sensitive, it slows glucose absorption in the intestine, and slows the production of glucose by the liver. ...Read more

Dr. David Sneid
1,026 doctors shared insights

Metformin (Definition)

That reduces liver production of glucose- other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk ...Read more


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What side effects are commonly associated with long term usage of glucophage (metformin) 850?

What side effects are commonly associated with long term usage of glucophage (metformin) 850?

Well tolerated: Metformin (glucophage) is effective in lowering glucose in diabetics, and treating the Insulin resistance of pcos. It can cause some diarrhea. It can cause lactic acidosis in people with kidney disease. Otherwise, it is quite well tolerated. ...Read more

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Doc has advised me to take glucophage (metformin) gor 3 months to regulate my hormones and aid in weight loss but i m wary. Will there be long term side effects?

Doc has advised me to take glucophage (metformin) gor 3 months to regulate my hormones and aid in weight loss but i m wary. Will there be long term side effects?

No: Metformin is excellent at reducing Insulin resistance, particularly when combined with diet, exercise, and weight loss. Most effective dose is 2000 md/d (1000 twice/day), but you need to work up to that dose gradually. ...Read more

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Is long term daily use of immodium to deal with diarrhea caused by metformin safe? Only take 2 immodium as directed on box

Is long term daily use of immodium to deal with diarrhea caused by metformin safe?  Only take 2 immodium as directed on box

Not advisable: If Metformin is causing that much symptoms to you, you might need to check with your doctor to consider changing it. Long term use of Immodium has its side effects on the colon and I would not advise you to do so ...Read more

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Any suggestions on supplement while taking long term metformin for PCOS/ insulin resistance? related to reduced vitamin/mineral absorption? Thnx!

Any suggestions on supplement while taking long term metformin for PCOS/ insulin resistance? related to reduced vitamin/mineral absorption?  Thnx!

Weight loss: Getting your body to your ideal body weight is the most important step in managing PCOS. If you are overweight then work on weight control. This is the key. Mineral supplementation is not needed. ...Read more

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How long until metformin side effects stop?

How long until metformin side effects stop?

Within a week: Metformin often induces mild GI upset which subsides within a week or so of initiating or increasing the dose. If effects do not subside one should consider reducing or discontinuing the dose. ...Read more

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Metformin side effects, how long do they last?

MAYBE indefinitely: Metformin has G.I. Side effects including diarrhea and abdominal cramps. The symptoms may last as long as you are taking the medication. One solution is generic glucophage xr or er which is a long-acting medication with less side effects. Many patients can not tolerate metformin at any dose but fortunately we have many diabetes meds --out there. Hope you are better soon! ...Read more

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How long does it take to for side effects to stop after discontinuing metformin?

Days: If they're due to metformin, they will stop within sever days. If they continue, they're due to something else. ...Read more

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How long does it take 500mg of metformin to get out of the system and what are the side effects?

How long does it take 500mg of metformin to get out of the system and what are the side effects?

Metformin: Main side effect of metformin is abdominal cramping, gas and diarrhea. 500 mg is a small dose. Talk to your doctor if you plan to stop any medication. The half life for the immediate release metformin is about 6 hours. ...Read more

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How long do I have to take metformin?

How long do I have to take metformin?

Possibly life long: It depends on why you're taking it. For most things, like diabetes, you take it as long as it gives you some benefit without excessive adverse events. ...Read more

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Please tell me how long it takes for metformin to work?

A few days: You should start to see improvement in your blood sugars within a few days, and continued improvement over a few weeks. ...Read more

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How long does it take metformin to work for fertility. Or does it even work?

How long does it take metformin to work for fertility. Or does it even work?

It helps, not sure : If you have the so-called polycystic ovarian syndrome and Insulin resistance problem with lower chance of fertility, the use of metformin can help, but no one really knows how truly effective it is or how long it takes. You could be pregnant tomorrow, next month, in 6 months, a year, or even never. It is frustrating, but hang in there. Wt loss can help. Consult doc regularly and good luck to you. ...Read more

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How long does it take before you start losing weight on glucophage (metformin)?

How long does it take before you start losing weight on glucophage (metformin)?

Right away...but.: Glucophage (metformin) works by making Insulin work better in your body. This helps lower appetite and does not cause any weight gain. Any weight loss you have will be due to your proper attention to diet and exercise. That said, you should have better results dieting while taking the metformin than if you weren't taking it. ...Read more

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Had my first B12 shot the other day. How long is it good for. And when should I get my next one. Been on Metformin for years and feel so much better.

Had my first B12 shot the other day. How long is it good for. And when should I get my next one. Been on Metformin for years and feel so much better.

Depends: How much vitamin B12 was injected? 1000 microgram dose should be good for a month, if not longer. It would be good to discuss the matter with your doctor who knows more about your health. ...Read more

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How long does it take the drug metformin to expire?

How long does it take the drug metformin to expire?

Expiration: Most drugs expiration date is a year. Some drugs less. There have been studies that looked at the efficacy of drugs post expiration and some were still effective as many as 20 years out. Best is to see your doc and see what's best for you. :) ...Read more

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How long does it take metformin to get in your system?

Soon: For lowering blood glucose, you will start to see the effects of metformin in a few days to a week. For pcos, it may take longer (several months) to see a normalization of periods, fertility, etc. ...Read more

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How long should metformin be used in pco's? will this medicine help?

How long should metformin be used in pco's? will this medicine help?

For some patients: Some patients with PCOS struggle with Insulin resistance. In this subset of PCOS patients Metformin can be used. There is not set duration for treatment and each case should be assessed individually. ...Read more

Dr. Walter Futterweit
675 doctors shared insights

Glucophage (Definition)

Glucophage is a diabetes-related agent which is a kind of ...Read more