Doctor insights on:
Long Term Effects Of Lupron
What are the long term effects of lupron (leuprolide)? Why are so many women asking to have it taken off the market?
I was given Provera 2x a day (08/01 to 08/26) to stop bleeding eventhough I had Lupron shot last 06/26. Any bad effects of long term use of Provera?
Provera: Provera can be used safely for various times depending on what problem is being addressed. Since you have been treated with Lupron and Provera it sounds like your issue may be fairly complex. Consider scheduling follow up with your Obgyn to clarify the diagnosis, the treatment plan and the time line for treatment ...Read more
1 or 3 months: Lupron (leuprolide) comes in 1 or 3 month doses (3.75 or 11.25 mg) and these injections usually cause menopause symptoms which I've seen as both mild or severe. It rarely continues beyond the treatment period & is a good way to pre-treat or reverse endometriosis or to shrink fibroid tumors prior to surgery. Discuss with your doc if your symptoms are severe or if you need estrogen to counter the severe effects. ...Read more
Varies: There are three forms of lupron, (leuprolide) one is a subcutaneous injection daily which will wear off very quickly. The second type is a depot form which last for approximately 30 days in the body, and lastly there is a 90-day form. A woman will usually ovulate 2 to 4 weeks after the effects of the Lupron (leuprolide) has worn off. ...Read more
How long after stopping lupron (leuprolide) for endometriosis will it take for your body to go back to normal?
Few days: Even though half-life of Lupron (leuprolide) is only 3 to 4 hrs plasama levels will remain high for few more days ( missing one dose is not a big problem). ...Read more
How long till 11.25mg lupron (leuprolide) wears off? I don't feel symptoms from it last shot was sept my husband & I want ttc should we wait? If so, how long ttc?
3 months: The shot lasts 3 months. It can have some effects a little longer. You don't have to wait at all. There is no danger in becoming pregnant but you may not ovulate. ...Read more
No time limit: It really depends upon its benefit to your husband. Men with metastatic disease can have long term benefit. ...Read more
Usually: Within 1 cycle or 1 month. Good wishes. ...Read more
Depends: Why are you taking the Lupron (leuprolide)? Is the underlying condition such that it is safe to proceed? You need to discuss this with your doctor who I suppose operated on you to diagnose the condition. In general, yes,after 3 months passes you might start ovulating and it will be a chance to get pregnant ...Read more
It depends: Lupron (leuprolide) does not directly improve pregnancy rates. It actually works to suppress ovulation and prevent pregnancy. There is a misperception that it can be used to improve pregnancy rates in people with endometriosis. Lupron (leuprolide) can be used as an adjunct in fertility treatments. If you have a fertility problem, it is best to see a specialist — a reproductive endocrinologist. ...Read more
How long does it take for lupron (leuprolide) depot to get out of your system, trying to conceive?
Depends on the dose: If you had the three month it could be up to four months. If you had the monthly, more than likely ok at six weeks. ...Read more
After having a 3 months dose of lupron (leuprolide) injection, after how long till my menstrual cycle be back to normal?
Variable: Lupron (leuprolide) suppresses estrogen production from the ovary. Ovulation usually does not occur but Lupron (leuprolide) is not considered a contraceptive hormone. Menstrual bleeding does not normally occur with Lupron (leuprolide) administration but periods should resume within six months of stopping this medication. ...Read more
Can prolonged lupron (leuprolide)&danazol, 18 months of injections total for lupron (leuprolide) & 4 yrs of danazol, incr risk of leukemias? Weird symptoms, dr's ref'd to oncology
No.: Danazol can be associated with benign liver tumors. There is no malignancy associated with either drug that I am aware of, and certainly not any of the leukemias. ...Read more
How long does it usually take for lupron (leuprolide) depot to begin altering a woman's menstrual cycle?
Different for All: In general, Lupron (leuprolide) will stop menstruations but exactly when it takes effect is a bit debatable and likely different for all women. In general the effect is seen after 2 weeks (following an initial hormonal surge). ...Read more
I'm taking lupron (leuprolide) 3.75mg and just took the 6th shot. How long before ttc? Is it safe for the baby if I get pregnant on the 1st month after last shot?
Make sure: You know (and are treating), your mthfr genotype status. At 35, you are at high risk. 84% of the population has at least one gene problem which causes increased risk for miscarriage, neural tube defects, and add or autism spectrum disorders. If +, do not take a prenatal vitamin with regular folic acid, it blocks the receptors, needs to be l-methylfolate. Neevodha is an option. Sorry tangent from? ...Read more
Off lupron (leuprolide) for 3+ mo. Going to take ocp to bring back af. Going to stop after I get 1st cycle bc I want to ttc. How long after last pill can I try ttc?
3 months: Waiting 3 months allows the lining of the uterus (the layer that nourishes the fertilized egg) to get back to baseline. ...Read more
After a single 3-month dose of Lupron Depot, how long until I should expect my menstrual cycle (and pain) to come back?
Varies: It may be as much as 2-3 months after the Depo wears off to regain normal cycles. It can vary from person to person ...Read more
I am on lupron in order to shrink my submicous fibroid and also control prolonged bleeding, wht are chances that I can get pregnant while on lupron.
By far, the most common side effect is hot flashes, because Lupron (leuprolide) causes a temporary menopause. Poor sleep resulting in emotional side effects or head ache are also common. A serious effect from long-term Lupron (leuprolide) is osteoporosis. Many of these side effects are reduced or eliminated with extra "add-back" hormones.
Some women have no side effects at all. ...Read more
Terrible: Lupron (leuprolide) causes reversible menopause. So as soon as the medicine takes effect the estrogen drops to zero same as complete menopause. Hot flashes, night sweats, moods, memory issues and joint pain etc. Many dr. S use this for endometriosis but endo is a surgically treated disease. Lupron (leuprolide) only temporarily diminishes symptoms but makes people miserable. Excisional surgery is needed via laparoscopy! ...Read more
Usually Mild: When I treat patients with Depo-Provera Lupron (leuprolide) (for instance for endometriosis) i usual;y use add back therapy, this is a second medicine used to prevent the side effects from lupron (leuprolide). The addback usually reduces or gets rid of any hot flashes, any vaginal dryness, or any mood swings. So in this way i usually prevent side effects from ever occurring. ...Read more
If I had my last lupron (leuprolide) injection on dec 19th, and I'm trying to conceive. Will the effects continue this month or harm a possible implantation?
It's safe: Lupron (leuprolide) is often used as a part of the preparation for an in vitro fertilization cycle. The medication is given in different dosages depending upon the purpose for it. But regardless, if you are able to ovulate, and conceive, it should not interfere with implantation, especially this long since your last dose. Good luck! ...Read more
Usually none: No specific effects for birth control pills used after lupron (leuprolide). ...Read more