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Doctor insights on: Long Term Effects Of Glyburide

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Dr. Titus Duncan Dr. Duncan
Bariatrics
39 years in practice
University of Oklahoma College of Medicine
1

1
Are there long term effects of diabetes medication (glyburide, metformin)?

Are there long term effects of diabetes medication (glyburide, metformin)?

Not many: Glyburide is a sulfonourea (it forces your pancreas to produce more insulin). Metformin does three things... It helps your Insulin work better by making the Insulin receptors in the body more sensitive, it slows glucose absorption in the intestine, and slows the production of glucose by the liver.

Dr. Luis Curet
131 Doctors shared insights

Glyburide (Definition)

Used with diet and exercise to help control blood sugar in patients with type 2 diabetes. It is an antidiabetic drug in a class of medications known as sulfonylureas, closely ...Read more


Dr. Arthur Heller Dr. Heller
Internal Medicine - Gastroenterology
39 years in practice
Jefferson Medical College of Thomas Jefferson University
2

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Overdosed w/glyburide (190pills) dec2011, now I'm experiencing a lot of nausea (not pregnant).Could it be a long term affect from the overdose?

Overdosed w/glyburide (190pills) dec2011, now I'm experiencing a lot of nausea (not pregnant).Could it be a long term affect from the overdose?

Doubtful: The meds are out of your system. It is unlikely you would have a long-term reaction. Follow up with your doc.

Dr. Grace Akoh-Arrey Dr. Akoh-Arrey
Pharmacology
12 years in practice
Florida International University College of Medicine
3

3
How long does it take for glyburide to become effective?

How long does it take for glyburide to become effective?

Varies (1 - 2 hours): Depending on the formulation ingested (micronized (glynase) or conventional Glyburide (diabeta, micronase)) onset of action ranges from about 1 to 2 hours with a maximum reduction of blood sugar seen within 3-4 hours. May last in body for over 18 to 24 hours. Should be taken with breakfast or main meal of the day to help reduce symptoms of low blood sugar (tremors, sweating, irritable, fatigue).

Dr. Alan Ali Dr. Ali
Psychiatry
28 years in practice
University of Arkansas for Medical Sciences/UAMS College of Medicine
4
Dr. Yash Khanna Dr. Khanna
Family Medicine
53 years in practice
University of Lucknow, K. G. Medical College
5

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What are effects of the medication diabeta (glyburide)?

What are effects of the medication diabeta (glyburide)?

DIABETA-GLYBURIDE: Diabeta (glyburide) is a Glyburide generic name, it is used to treat type 2 diabetes along with diet and exercise.It brings the blood sugar down and can sometime cause hypoglycemia.If you skip a meal, exercise too long, drink alcohol, or are under stress.

Dr. Alan Ali Dr. Ali
Psychiatry
28 years in practice
University of Arkansas for Medical Sciences/UAMS College of Medicine
6
Dr. Thomas Knecht Dr. Knecht
Internal Medicine - Endocrinology
27 years in practice
UC San Diego School of Medicine
7

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Do you know if there are side effects from taking glucovance (glyburide and metformin)?

Do you know if there are side effects from taking glucovance (glyburide and metformin)?

Glucovance (glyburide and metformin): Hi. Glucovance (glyburide and metformin) (metformin + glyburide combination) is not one of my preferred type 2 drugs. But it's inexpensive and will help for awhile before losing effective. Metformin side effects (assuming normal kidney function) are GI (things like nausea, diarrhea). Glyburide side effect is low but real risk of hypoglycemia. If you have decent insurance, there are better type 2 drugs out there. Good luck!

Dr. Mark Rasak Dr. Rasak
Internal Medicine - Cardiology
29 years in practice
The University of Iowa Roy J. and Lucille A. Carver College of Medicine
8
Dr. Jesse Krakauer Dr. Krakauer
Internal Medicine - Endocrinology
41 years in practice
Stanford University School of Medicine
9

9
Can I take my Invokana and Glyburide after my scan?

Can I take my Invokana and Glyburide after my scan?

Probably: B"sd In general glyburide and other sulfonamides are well documented to increase risk of MI about 20% - there are safer options. Invokana is a SGLTP2i- sodium glucose transport protein inhibitor, that results in sugar in the urine. It has actually been shown to protect kidney function over the long term. It also has a diuretic effect so should skip if you are dehdrated from scan or other reason

Dr. Richard Ogletree Dr. Ogletree
Pharmacology
years in practice
10

10
What is glyburide? I'm taking it twice in the morning for my diabetes

What is glyburide? I'm taking it twice in the morning for my diabetes

An insulin releaser: Glyburide (called glibenclamide outside the U.S.) Is a sulfonylurea anti-diabetic agent. It causes the pancreas to release insulin. It can do this even in the absence of food, so can cause the sugar to get too low. Glyburide can be a problem in the elderly, again because of the risk for low blood sugar. If you take this medicine, it could be dangerous to skip meals.

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Dr. Quang Nguyen Dr. Nguyen
Internal Medicine - Endocrinology
years in practice
Midwestern University Arizona College of Osteopathic Medicine
11

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I have recently gotten diabeta (glyburide) and what are some good food choices?

I have recently gotten diabeta (glyburide) and what are some good food choices?

Many options: When choosing a diet, make sure it's one that you can maintain lifelong so do not do anything drastic. In general, you should eat lots of vegetable and fruits. Non-starchy vegetables are best: spinach, carrots, broccoli or green beans. Eat whole grain foods instead of processed food (whole wheat over white breads) add fish to your meals 2-3 times per week. Dry beans & lentils are good protein...

Dr. Thomas Knecht Dr. Knecht
Internal Medicine - Endocrinology
27 years in practice
UC San Diego School of Medicine
12

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What difference is there between glyburide and glimepiride medications?

What difference is there between glyburide and glimepiride medications?

Same family: Hi. Glyburide is a second generation sulfonylurea and glimepiride is a 3rd generation. They work at the same receptors on the beta cell (the pancreatic cells that make insulin) and stimulate insulin release. Glimepiride is preferable because of less metabolite build up in kidney disease, but they're VERY similar. I never use them. In my opinion, based on good science, we have much better drugs.

Dr. Michael Kleerekoper Dr. Kleerekoper
Internal Medicine - Endocrinology
47 years in practice
University of Sydney Faculty of Medicine
13

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What difference is there between glyburide and glimepiride medications?

What difference is there between glyburide and glimepiride medications?

Diabetes: Either glyburide or glimepiride can be prescribed for management of diabetes. There may be a cost difference in your favor or you doctor may have a good reason to prescribe one or the other. More important - you need to take control of your eating habits, your weight (if overweight), and your exercise. Also please remember to measure your blood sugar regularly. Your doctor will advise you on dose

Dr. Mark Rasak Dr. Rasak
Internal Medicine - Cardiology
29 years in practice
The University of Iowa Roy J. and Lucille A. Carver College of Medicine
14
Dr. Thomas Knecht Dr. Knecht
Internal Medicine - Endocrinology
27 years in practice
UC San Diego School of Medicine
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Please explain what are the differences between glyburide and glimepiride medications?

Please explain what are the differences between glyburide and glimepiride medications?

Similar mechanisms: Hi. Glyburide & glimepiride (& glipizide & others in the sulfonylurea class, for that matter) all work by the same mechanism to stimulate endogenous insulin release. They differ in duration of action, metabolites, accumulation in kidney disease, etc. They're archaic drugs that I never use anymore. There are much better type 2 drugs out there. Their one benefit - they're cheap.

Dr. Michael Sparacino Dr. Sparacino
Family Medicine
33 years in practice
A. T. Still University Kirksville College of Osteopathic Medicine
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Can metaformin, fosinpril, glyburide, simvastain, or omenprazole cause mood swings?

Possibly: Its possible that any one of these medications or any combination could cause mood swings. Call your doctor.

Dr. Richard Shewbridge Dr. Shewbridge
Internal Medicine - Endocrinology
29 years in practice
Wayne State University School of Medicine
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What is diabeta (glyburide)?

Diabetes pill.: Diabeta is a brand of the medication glyburide. It is an effective treatment for type 2 diabetes. It is available as generic Glyburide (lower in cost). It may not be the safest of this class, known as sulfonylurea medications, however (concerns about hypoglycemia in patients with kidney disease and heart effects in patients with heart disease).

Dr. Mark Rasak Dr. Rasak
Internal Medicine - Cardiology
29 years in practice
The University of Iowa Roy J. and Lucille A. Carver College of Medicine
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Micronase (glyburide) --how is it used?

Type 2 diabetes: This is an older sulfoaurea medication used for type 2 diabetes.

Dr. Michael Dansie Dr. Dansie
Family Medicine
12 years in practice
University of Utah School of Medicine
19

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Please describe the medication: glyburide?

Please describe the medication: glyburide?

Diabetes medication: Used with diet and exercise to help control blood sugar in patients with type 2 diabetes. It is an antidiabetic drug in a class of medications known as sulfonylureas, closely related to sulfa drugs.

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Dr. Grace Akoh-Arrey Dr. Akoh-Arrey
Pharmacology
12 years in practice
Florida International University College of Medicine
20

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What are potential problems with glyburide?

What are potential problems with glyburide?

Hypoglycemia: Prolonged hypoglycemia (mild to severe -low blood sugar- noted as tremor, sweating, headache, fatigue, confusion) is the most common/ concerning side effect of glyburide, this is due to its long half- life / active metabolite compared to other 2nd generation sulfonylureas. Minor weight gain seen. Nausea, heartburn (GI) are transient/ dose related. Rash/itching may occur. Liver injury is rare.

Dr. Sheila Smith
24 Doctors shared insights

Glynase Prestab (Definition)

Glynase PresTab is a second generation sulfonylurea which is a kind of diabetes-related drug ...Read more


Dr. Jan Lei Iwata
25 Doctors shared insights

Micronase (Definition)

Micronase is a second generation sulfonylurea which is a kind of diabetes-related drug ...Read more