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Doctor insights on: Long Term Effects Of Famotidine

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Safe to take Pepcid (famotidine) AC (20mg) daily? Works wonders for me. Concerned about long-term effects the medication might have on me however.

Safe to take Pepcid (famotidine) AC (20mg) daily? Works wonders for me. Concerned about long-term effects the medication might have on me however.

Check with MD: as to why you need to be on any antireflux/acid reducing medicine. Rule out problems that might occur over thr long term; address other issues re: weight, meds, alcohol, diet, tobacco, that may affect reflux and GERD. Lowest dose of least potent med for shortest period of time to do the job is a reasonable approach. Chronic reflux canlead to problems, including esophageal cancer. See MD ...Read more

Dr. Shari Jackson
224 doctors shared insights

Famotidine (Definition)

This is a drug that belongs to the h2 blocker group. By blocking the h2 receptor in the stomach it leads to a reduction in the production of acid. This beneficial effect is what makes it useful in the treatment of gastritis, ulcers ...Read more


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I'm Asian and i take Pepcid (famotidine) before i drink alcohol to reduce redness/flushness. If I do this 2-3x/week for several years, are there long term effects?

I'm Asian and i take Pepcid (famotidine) before i drink alcohol to reduce redness/flushness. If I do this 2-3x/week for several years, are there long term effects?

Fatty liver: Alcohol affects the way the liver process fat so your liver cells get stuffed full of it. If you drink often it can make your liver get fat – reducing your consumption can help it return to its normal size. You can spend half of your life damaging your body/liver and not feel any of the effects.
Moderation is the key with or without pepcid (famotidine). ...Read more

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Which is associated with more/less possible adverse health effects from long term use? Prilosec or pepcid (famotidine)?

Which is associated with more/less possible adverse health effects from long term use? Prilosec or pepcid (famotidine)?

Heartburn meds : Both PPI's, such as Prilosec, and H2-blockers, such as Pepcid, (famotidine) are frequently used medications for Gerd. Both of these classes of medicines are reasonably safe, and if needed can be used long-term generally very safely. If you have severe symptoms, I would not shy away from using whichever controls your symptoms the best. Be sure to follow anti-reflux precautions! Good luck. ...Read more

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Can I take Pepcid (famotidine) AC everyday for GERD? Instead of Prilosec. I heard Prilosec can cause negative side effect with long term use

Can I take Pepcid (famotidine) AC everyday for GERD? Instead of Prilosec. I heard Prilosec can cause negative side effect with long term use

Yes: It's OK to take either one of those medications every day for reflux disease. You should, however, when yourself after three months and see what happens with your symptoms. If your symptoms come back, see your primary care provider for more options. Hope this helps! ...Read more

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Pepcid (famotidine) AC (20mg) (almost) daily ok? Any possible adverse long term issues? Not asking about my GERD. My GP. ruled out anything serious.

Pepcid (famotidine) AC (20mg) (almost) daily ok?  Any possible adverse long term issues? Not asking about my GERD.  My GP. ruled out anything serious.

It is safe: the safety record for pepcid (famotidine) have been established so you do not have to worry about that but any medicine we balance between the benefit and the potential side effect so it really depend on why you are taking it and is it helping i hope that will answer your question good luck and thank you for using health tap ...Read more

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Been getting acid reflux (felt in throat) daily. 10mg or 20mg of famotidine stops it every time. Is famotidine damaging long term?

Been getting acid reflux (felt in throat) daily.  10mg or 20mg of famotidine stops it every time.   Is famotidine damaging long term?

Chronic acid reflux: Pepcid (famotidine) is fairly safe medicine for long term use. If you have recurrent symptoms have yourself checked out for infection or ulcer and appropriately treated. ...Read more

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What's more effective for acid reflux, 300mg of ranitidine or 20mg of famotidine ? Which one is likely to last longer, the effects ?

About the same: Ranitidine and Famotidine are h2 receptor antagonists, and their efficacy at reducing acid and relieving reflux symptoms are about the same. For more long lasting relief, a proton pump inhibitor, such as omeprazole, would be a better choice. ...Read more

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How long does it take to get to stable levels of Pepcid (famotidine) 20mg taken twice a day?

How long does it take to get to stable levels of Pepcid (famotidine) 20mg taken twice a day?

15hrs: it takes 5 half-lives to get up to stable levels and about that much time to get something out of your system. Pepcid (famotidine) has a half-life of 2.5-3.5hrs so you should reach stable levels after 15hrs, give or take. ...Read more

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Is that healthy taking 80mg pantoprazole plus 40mg famotidine for a long time ?I have losing my weight unintended by about 10 kg , so is cancer signs?

Is that healthy taking 80mg pantoprazole plus 40mg famotidine for a long time ?I have losing my weight unintended by about 10 kg , so is cancer signs?

Gastroduodenal ulcer: Not necessarily cancer. Need to get tested for h pylori + peptic ulcer and get on antibiotics for 2 weeks is you have this. Neuroendocrine tumor such as zes is also possible after this much acid suppression for this long. You need an upper endoscopy and internal med/gi eval. ...Read more

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Is there any side effect of pepcide (famotidine) for 5 week old? My concern is on long run and stomach acids impact of the dose (if any)?

Is there any side effect of pepcide (famotidine) for 5 week old? My concern is on long run and stomach acids impact of the dose (if any)?

Probably not: Not clear what you would be treating a 5 week old with Pepcid (famotidine) for without a physician's input? In any case if you give a low 5 -10 mg dose maybe some sedation would be expected but i don't think that i would use Pepcid (famotidine) for long though. See your doctor this might be an intolerance to formula or even breast milk sometimes. ...Read more

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Ive had gastritis for two weeks. I think the cause was taking doxycycline tablets without water. I am taking Pepcid (famotidine) now, how much longer will this go?

Ive had gastritis for two weeks. I think the cause was taking doxycycline tablets without water. I am taking Pepcid (famotidine) now, how much longer will this go?

Variable: General info: Symptoms of gastritis due to an irritant like doxycycline generally improve within days of stopping the irritant. Proton pump inhibitors (eg.omeprazole/Prilosec) help healing much more than treatment with H2 blockers (eg Pepcid). Persistent symptoms need clinic evaluation for possible ulcers, or for H. pylori infection which can delay healing & is treated with a combination of meds. ...Read more

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Gastritis moderate severe non-erosive in the antrum and body of the stomach how long does it take to heal? using Prilosec protonics and pepcid (famotidine)? had v&p in 1976 is the acid not shut down properly?

Gastritis moderate severe non-erosive in the antrum and body of the stomach how long does it take to heal? using Prilosec protonics and pepcid (famotidine)? had v&p in 1976 is the acid not shut down properly?

Approx. 8-12 weeks: Assume the diagnosis was made by EGD. Biopsy for H. Pylori must be taken. If it was negative then PPI and H2 blocker as you are taking is the right treatment for 12 weeks. And if symptoms continue , one can continue for longer period of time.
Avoid Alcohol, NSAID/Aspirin/Cigarette/Spicy and fatty food. ...Read more

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Are confusion and seizures side effects of pepcid (famotidine)?

Are confusion and seizures side effects of pepcid (famotidine)?

Can be: Pepcid (famotidine) and other acid-suppression drugs (ppis) are commonly used, for long periods of time for various stomach conditions - and not always needed. First, almost any side effect can happen with almost any drug, and each person can have their "own" side effect. In general however, seizures are very uncommon with ppis but can happen. Confusion is a little more common esp in older folks. ...Read more

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Can i take generic Pepcid (famotidine) 20 mg 2x daily and sucralfate 1/2 gram 3x daily each day without any side effects?

Can i take generic Pepcid (famotidine) 20 mg 2x daily and sucralfate 1/2  gram 3x daily each day without any side effects?

GI meds: Hello, the medications you are taking are used for gerd, gastritis with possible peptic ulceration. The medications are very helpful especially when used together. The dosing looks good. Side effects can occur with any medication. Be sure to see your doctor, especially if you suspect and problems are still occurring. Sometimes an endoscopy and eval for a bacteria called h pylori may need treatment. ...Read more

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Can 10mg famotidine cause diarrhea? I take it nearly daily & never get side effects. But I got diarrhea 1 hour after taking it today. Related?

Can 10mg famotidine cause diarrhea?  I take it nearly daily & never get side effects.  But I got diarrhea 1 hour after taking it today.  Related?

Famotidine : Although famotidine can rarely cause diarrhea, the fact that you can take it on a regular basis without side effects make it more likely that today's episode is not due to the medication. If your diarrhea persists on a regular basis, you may need to switch medications. Drink plenty of fluids to remain well hydrated until the diarrhea passes. Good luck. ...Read more

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Is pepcid (famotidine) better to take than prilosec? Ive heard prilosec can cause magnesium deficiency and pepcid (famotidine) generally has no adverse side effects. True?

Is pepcid (famotidine) better to take than prilosec? Ive heard prilosec can cause magnesium deficiency and pepcid (famotidine) generally has no adverse side effects. True?

Not true: Side effects of prilosec are very rare and tend to occur in sick and hospitalized patients. If pepcid (famotidine) doesn't work and prilosec does work then stick with prilosec. You can have you magnesium check every few years for reassurance. ...Read more

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Does expired Pepcid (famotidine) AC work?

Pepcid (famotidine): Not advised to consume expired medications.

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Will expired Pepcid (famotidine) still be effective ?

Will expired Pepcid (famotidine) still be effective
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Yes: Most medicines may still work years after the expiration date, but the effect may be weak or unpredictable. There are few medications that never should be taken after the expiration date ( example : : tetracyclines. Avoid liquid antibiotics, insulin, & nitroglycerine).If the expiration date passed a few years ago and it's important that your drug is absolutely 100% effective get a new bottle. ...Read more

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Can i take Pepcid (famotidine) AC if it expired in 2010?

Probably: May not be as effective. Doubt it will do anything harmful. Why don't you just go buy some unexpired tablets? ...Read more

Dr. Ronald Krauser
253 doctors shared insights

Pepcid (Definition)

Pepcid is a H2 receptor blocker which is a kind of ...Read more