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Doctor insights on: Long Term Effects Of Bupropion

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Are there long-term effects of wellbutrin (bupropion)?

Are there long-term effects of wellbutrin (bupropion)?

Officially, none: No warnings about long-term use of wellbutrin (bupropion) have been issued. But, you have to realize that its makeup is similar to amphetamine, and is dopamine-enhancing. It can cause jitteriness, twitching, and seizures even in short-term. It can be difficult to wean from, because of irritability and anger -- not unlike nicotine withdrawal for which it is used (as zyban). Ongoing need should be reviewed. Read more

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Dr. Alan Ali
788 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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Anyone have problems with long term wellbutrin (bupropion) use?

Anyone have problems with long term wellbutrin (bupropion) use?

Generally no: Wellbutrin (bupropion) as a long term medication to treat and prevent major depression is generally safe and does not cause any known harm. Read more

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Is taking 100mg of nortriptalyne with 150mg of bupropion X-R long term safe? Is this a healthy liver combo for someone who used to drink very heavily?

Is taking 100mg of nortriptalyne with 150mg of bupropion X-R long term safe? Is this a healthy liver combo for someone who used to drink very heavily?

Risky combination: Combining these medications may increase the risk of seizures, which may occur rarely with either medication. In addition, buPROPion can increase the blood levels of nortriptyline, which may increase other side effects. Ref: https://www. Drugs. Com/interactions-check. Php? Drug_list=440-0, 1734-0 Read more

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My doc has prescribed me 1mg Xanax, (alprazolam) 10mg Lexapro and just added 150mg Wellbutrin XL. Is this allowed? Will this cause long term problems?!

My doc has prescribed me 1mg Xanax, (alprazolam) 10mg Lexapro and just added 150mg Wellbutrin XL. Is this allowed? Will this cause long term problems?!

Medication effects: I understand your concern.
Reflect on symptoms of Anxiety and Depression effect on your relationships, work and personal life; medication need for anxiety or depression; then discuss medication interactions, benefits and side effects; Therapy.

Wellbutrin with Lexapro may increase the risk of seizures.
Using Xanax (alprazolam) with Lexapro may increase dizziness, confusion, and difficulty concentrating.
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What are the risks of taking wellbutrin (bupropion) and Zoloft long term? Being used to treat ADHD and OCD respectively

What are the risks of taking wellbutrin (bupropion) and Zoloft long term? Being used to treat ADHD and OCD respectively

Not clear: There is conflicting data regarding use of antidepressants later in life and all cause mortality although there is the notion that the medications are relatively benign. There is always going to be a risk benefit analysis that is necessary in addition to the number needed to treat or a number needed to harm with any medication reflecting the capacity to do both good and bad things to patients. Read more

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I just started on 100mg of wellbutrin (bupropion) for 5 days then up to 300mg. How long before I feel the effects?

I just started on 100mg of wellbutrin (bupropion) for 5 days then up to 300mg. How long before I feel the effects?

Depends...: Most antidepressants take about 2 weeks or so before you notice the therapeutic effects. However you can experience side effects after the 1st dose. Read more

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How long does it take to feel the effects of Wellbutrin (bupropion)? I've been on it for 5 weeks and still feeling down.

4-6 Weeks: Bupropion is an antidepressant that works primarily by increasing dopamine.

If you have had absolutely no improvement in your depression, you may be on too low of a dose, or this may just be a medication that doesn't work for you.

Also make sure you have the right diagnosis.

Do NOT discontinue this without consulting your psychiatrist, but I would bring this up with him/her. Read more

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What are my chances of becoming more social and confident by taking Bupropion with Abilify (aripiprazole)? How long to see the effects?

Indirect: Certainly thse medicines were not designed to increase one's social skills and confidence. They are effective more often than placebo for the treatment of depression, and in the case of Abilify, (aripiprazole) also for bipolar disorder and some thought disorders. Psychotherapy is often helpful in working on more longstanding issues such as confidence and social anxiety. Good luck Read more

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Wellbutrin (bupropion) was causing bad nausea/indigestion, I was on it for 3 weeks, stopped med, how long till those side effects go away?

Roughly speaking?: Anywhere between 60-150 hrs. Pretty much everything should be cleared out of your system. So if we average that range out I'd say around 100 hrs. From your last dose you should be Wellbutriin Clean from your bloodstream. Read more

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Stopped taking Wellbutrin (bupropion) because of the bad side effects on Wednesday but I'm still really sick to my stomach & back pain. How long does it take?

Stopped taking Wellbutrin (bupropion) because of the bad side effects on Wednesday but I'm still really sick to my stomach & back pain. How long does it take?

Wellbutrin (bupropion) is: Reported to have a half-life of 21 hours, but another source says 33 to 37 hours. It is absorbed slowly and therefore might be out of your blood relatively soon (less than a week) but still in your system for several weeks. Here's a beginning reference:

http://prescription-drug. Addictionblog. Org/how-long-does-wellbutrin-stay-in-your-system/ Read more

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3oomg Wellbutrin no longer working. Depression worse. What can I ask dr to add. Cymbalta (duloxetine) gave brain zaps. Need no side effects?

3oomg Wellbutrin no longer working. Depression worse. What can I ask dr to add. Cymbalta (duloxetine) gave brain zaps. Need no side effects?

Speak with your doc: If you were started onWellbutrin to help with smoking cessation or other addictive habits you may need an add on. If your doctor speaks with you she can help you decide to add another antidepressant or switch it for an other antidepressant. Each one has different strengths and your doctor will be familiar with your case and be able to make the best choice or make a referral to another psych. Read more

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How long does it take for bupropion HCl to start to work?

How long does it take for bupropion HCl to start to work?

Generally 3-4 weeks: Most antidepressants take 3-4 weeks to show an effect. The best results usually come with a combination of psychotherapy and medication, rather than just using the medication alone. Read more

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How long after stopping wellbutrin (bupropion) can I drink?

Wellbutrin, (bupropion) Alcohol: Commend yourself if you did not use Alcohol while taking Wellbutrin (bupropion) for Depression.
Did you discuss with your Psychiatrist for gradual withdrawal of Wellbutrin (bupropion), possibly 6 weeks to avoid withdrawal symptoms.
It gets out of system in about 7 days.
See a Psychiatrist if you have history of Alcohol cravings, hangovers, blackouts, anxiety, depression, paranoia and memory problems; Attend AA meetings Read more

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I'm changing my medication from Effexor (venlafaxine) 300mgs to wellbutrin 150mgs. How long before I notice a change in my mood?

I'm changing my medication from Effexor (venlafaxine) 300mgs to wellbutrin 150mgs. How long before I notice a change in my mood?

Many Variables: When switching from one antidepressant to another it is difficult to predict how quickly the new medication will take effect. Generally one expects an antidepressant to begin to work after two weeks with the maximum benefit at six weeks. One should taper slowly off Effexor (venlafaxine) due to discontinuation symptoms. These would include anxiety and flu-like aches and pains. Work closely with your md. Read more

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I took wellbutrin for 2days 1xa day 150mg its making worse how long till out of system and can try something else want to try inderal.

3-5 days: If you were only taking wellbutrin for 2 days just to be safe I'd wait 3-5 days before starting inderal under your PCP direction naturally, but usually 2 days of a med like wellbutrin would have minimal adverse effects if any stopping it abruptly as you have done.
having said that any med changes should be closely monitored by you primary care provider. Read more

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Took wellbutrin 2 days and stopped cause I noticed sugar was 126 in am day 2 if this is the cause of elevation... How long to normalize? Not diabetic

See below: It's not advised to stop medication without the knowledge of prescribing provider. Please contact the doctor who prescribed the medication to figure out further steps. Good Luck! Read more

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Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more


Dr. Dariush Saghafi
185 Doctors shared insights

Zyban (Definition)

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