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Doctor insights on: Localized Myxedema

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If hypothyroidism is untreated, can myxedema coma occur?

If hypothyroidism is untreated, can myxedema coma occur?

Read about it: Myxedema coma is a relatively uncommon condition but it certainly can occur in persons with hypothyroidism. You can read about it by going to this link. http://www.aafp.org/afp/2000/1201/p2485.html. ...Read more

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Severe pedal oedema pitting, retro orbital swelling, ascitis , wbc 14500, platelets 800000. ?

Severe pedal oedema pitting, retro orbital swelling, ascitis , wbc 14500, platelets 800000.

?

See doctor now: You have a serious medical issue which needs be treated ASAP. There is not an issue which can be addressed in this forum. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes.does thismean allergic vasculitis?

Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes.does thismean allergic vasculitis?

No: There is no involvement of the blood vessels themselves- thus not vasculitis by definition. This is a very common skin biopsy finding which has no diagnostic meaning other than ruling out a more serious condition. ...Read more

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What is localized juvenile periodontitis?

What is  localized juvenile periodontitis?

LJP: Now called localized aggressive periodontitis - it is a form of periodontitis where the bacteria a.A. Affects the molars and incisors of juvenile aged people. ...Read more

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Is pitting edema caused by hypothyroidism?

Is pitting edema caused by hypothyroidism?

Possible: There are man causes of pitting edema. Most associated with capillary leakage of some sort in the extremities. This is often associated with cardiac dysfunction. However, there are many causes. Hypothyroidism in severe form is one of these causes. However, for specific information consult your doctor for more details. ...Read more

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Why swelling of eye lid happens in kidney disease stage 2 or advanced stage?

Why swelling of  eye lid happens in kidney disease stage 2 or advanced stage?

Fluid retention: With progressive renal dysfunction, kidneys lose the ability to regulate salt and water balance. This can cause fluid retention & present as swelling in the legs, hands, feet, face and even the abdomen if severe. Diuretic medications which increase urination can help, but treatment should be directed by a nephrologist (kidney specialist) who understands the cause in these more advanced cases. ...Read more

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Is pitting edema serious?

Is pitting edema serious?

Yes: Putting edema is due to significant fluid retention and it is one of the common sign of congestive heart failure. ...Read more

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Treatment of pitting pedal edema?

Treatment of pitting pedal edema?

Edema: The treatment depends on the cause of the pitting edema. When caused by congestive heart failure it is certainly different from when it is caused by venous insufficiency or hepatic cirrhosis. ...Read more

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Er/pr neg,her2+ Bca, left breast primary lump with skin mets on left mets, can brain mets develops without other visceral involvement?

Er/pr neg,her2+ Bca, left breast primary lump with skin mets on left mets, can brain mets develops without other visceral involvement?

Yes it can happen: Brain mets typically develop later in the course of breast cancer but they can occur anytime even as a presenting symptom on rare occasions. ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Vacuolar interface dermatitis, tight superficl perivascular & periadnexial lymphocytic infiltrate, mild incr. In dermal mucin. No fungus.-rash biopsy.?

Vacuolar interface dermatitis, tight superficl perivascular & periadnexial lymphocytic infiltrate, mild incr. In dermal mucin. No fungus.-rash biopsy.?

Varied possibilities: These findings suggest several possible entities.Based on this description of biopsy findings diagnoses including connective tissue disease such as lupus erythematosus may be considered, as well as a drug reaction. However, the only way to accurately make a diagnosis is to correlate the biopsy findings with the clinical presentation and other symptoms a patient may be having. ...Read more

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Is generalized epilepsy progressive?

Is generalized epilepsy progressive?

No: Epilepsy is either without known cause or related to an identifiable cause. Unknown cause may present in childhood, be easy to control, and be genetic in type. Identifiable cause is often partial type seizures and more difficult to control with association with serious medical disease. Primary generalized is usually unknown cause. Secondary generalized is usually identifiable with bad outcome. ...Read more

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Is systemic mastocytosis life-threatening?

Is systemic mastocytosis life-threatening?

Usually not: Most people with systemic mastocytosis (sm) have a normal lifespan. Episodes of anaphylaxis with sm can be dangerous if not treated properly, so it's important to use Epipen (epinephrine) and lay flat with the feet elevated slightly. Rarely, sm can be aggressive or associated with a leukemia. In these cases, lifespan may be shortened, but the sm may respond to chemo. See a specialist in masto for more info. ...Read more