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Doctor insights on: Lobular Carcinoma In Situ Lcis Symptoms

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What causes ductal carcinoma in situ (dcis)?

What causes ductal carcinoma in situ (dcis)?

Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more

Dr. Barry Rosen
4,351 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is invasive lobular carcinoma the same as invasive ductal carcinoma?

Is invasive lobular carcinoma the same  as invasive ductal carcinoma?

Different: Lobular carcinoma is less common and often does not form a lump. Please see these sites for more information. http://www.mayoclinic.com/health/invasive-lobular-carcinoma/ds01063 http://www.Mayoclinic.Com/health/breast-cancer/ds00328. ...Read more

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Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion.Is it cancer?

Yes: Adenocarcinoma in situ is cancer. The area suggestive of micro invasion suggests you should have rather aggressive followup screening which I am sure your doctor has, or will soon suggest. Stay on top of this and follow his/her advice. ...Read more

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Is cervical carcinoma in situ considered cancer or pre cancer?

Is cervical carcinoma in situ considered cancer or pre cancer?

Pre- cancer: It is good to seek treatment from a gynecologist as it will require some form of local therapy to either excise it or burn it off with Laser or cryotherapy. if done well it can be easily eradicated. ...Read more

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Where does invasive ductal carcinoma metastasize?

Where does invasive ductal carcinoma metastasize?

Many organs: The first likely tissue where metastases occurs in invasive ductal cancer is the lymph nodes on the armpit or behind the chest wall. Other organs may include the bones, lungs, liver, brain, adrenal glands, skin, bone marrow, the lining around the lungs or heart or the abdomen. Other parts of the body are less often sites of spread. ...Read more

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What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

What does this mean? Inverted papilloma with dysplasia and foci of in situ invasive squamous cell carcinoma (transitional)?

Premalignant: An inverted papilloma is a tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose and/or sinuses or in the urinary tract (bladder, renal pelvis, ureter, urethra).. With dysplasia and in-situ squamous Ca this would probably be a premalignant sinus carcinoma bordering on squamous cell Ca needing resection. ...Read more

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What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

What is inverted papilloma with dysplasia and foci of in situto invasive squamous cell carcinoma(transitional)?

Location: What is the source of the biopsy? In the paranasal sinuses inverted papilloma is a sinus tumor traditionally treated with surgery, especially if there are foci of carcinoma. ...Read more

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What are the survival statistics for breast cancer invasive ductal carcinoma?

What are the survival statistics for breast cancer invasive ductal carcinoma?

It depends on many f: Most women with localized breast cancer do very well and there is high cure rate. Overall 75%-80% of breast cancers are curable. But you need to know what stage of cancer it is? You should also know what subtype(there are 3 different types) of breast cancer it is. Further there is the matter of what type of adjuvant therapy(post surgery treatment) was used. I'am sure your oncologist can answeryr. ...Read more

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How are carcinoma in situ and benign neoplasm different?

Good question: And difficult to tell sometimes. The most straightforward way to put it is that a benign neoplasm will never turn into an invasive malignancy within your lifetime. Cis will eventually turn into one. But, because we don't live forever, cis might not turn into a malignancy during one's lifetime anyway. Pathologists can usually, but not always, tell the difference by microscopic cell exam. ...Read more

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Is invasive lobular carcinoma the same as invasive ductal ca?

Is invasive lobular carcinoma the same as invasive ductal ca?

No: Although both are breast cancers they are different in the significance attached to them. Lobular carcinoma is more likely to be larger, lymph node positive and estrogen positive then invasive ductal. A study in the ann surg oncol. 2010 jul;17(7):1862-9. Epub 2010 feb 17 suggests that invasive lobular carcinoma has a better prognosis stage for stage than invasive ductal carcinoma. ...Read more

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Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Complicated question: Carcinoids are carcinomas, usually more slow growing than adenocarcinomas. For information in this topic you may consult this link: http://www.webmd.com/cancer/carcinoid-tumors#1 ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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Mammogram with punctate pleomorphic calcifications. Is that breast cancer?

Mammogram with punctate pleomorphic calcifications.  Is that breast cancer?

Needs investigation: Although breast calcifications may not necessarily mean cancer, pleomorphic calcifications are suspicious. A biopsy should be done. Talk to your doctor. Pleomorphism means that something is of varying shape and characteristics. A non-cancerous or benign calcification will be read as "benign-appearing". Don't delay your biopsy. ...Read more

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What is ductal incarcinoma (breast cancer )?

What is ductal incarcinoma (breast cancer )?

Breast Cancer: Learn more about intraductal carcinoma of the breast at: http://www.Intraductalcarcinoma.Net/. ...Read more

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Have you diagnosed someone young with intraductal papilloma, carcinoma in situ or breast cancer?

Have you diagnosed someone young with intraductal papilloma, carcinoma in situ or breast cancer?

Yes: While these diagnoses are less common in young women, they do occur. If you have concerns, you should consider getting an ultrasound or a mammogram. ...Read more

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The decision was that I have lobular carcinoma in situ. What is it?

Also called lobular: Neoplasia...It forecasts that you will develop a breast cancer in either breast. Some used to do "mirror" biopsies. Others contemplate bilateral mastectomy. Lcis is a risk not a cancer, but the lobular invasive cancer can pose detection problems. Discuss this with a breast cancer team. I would watch very carefully. Lobular cancer makes up only 15% of invasive cancer. ...Read more

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Are there natural treatments for lobular carcinoma in situ?

Are there natural treatments for lobular carcinoma in situ?

Yes BUT: We need to consider that this is probably lobular "neoplasia" vs. Cis. That being said we still feel this is marker of increased cancer risk. We shouldn't neglect putting together fam history, other risk factors, limitations & risks in imaging, etc before discounting antihormonal therapy and rarely surgery. Many do choose close follow-up. Natural treatments may be incorporated with sufficient data. ...Read more

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What are the causes of breast and arm pain after having biopsy with lobular carcinoma in situ diagnosis?

What are the causes of breast and arm pain after having biopsy with lobular carcinoma in situ diagnosis?

LCIS : Lobular-carcinoma-in-situ (lcis) is a microscopic finding on breast biopsy that is associated with an increased risk of breast cancer in either breast of those affected. It is silent in that it causes no symptoms. Therefore, your breast & arm pain is unrelated to the diagnosis. Perhaps the pain is related to the biopsy procedure itself. If so, it should resolve pretty quickly. ...Read more

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Is mastectomy good for an invasive & in situ lobular carcinoma, stage 1b, sbr grade 2, 8 mm in size with good margins except anterior margin 1.5mm ?

Is mastectomy good for an invasive & in situ lobular carcinoma, stage 1b, sbr grade 2, 8 mm in size with good margins except anterior margin 1.5mm ?

Concern: The 1.5mm margin anteriorly is the only margin that gives me concern. For patients undergoing lumpectomy, obtaining at least a 2mm margin is associated with a decreased risk of recurrence. It would not be usual practice to take you back to surgery for a re-excision of this margin, however. ...Read more

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Is invasive lobular carcinoma the same as invasive ductal ca?

No: Although both are breast cancers they are different in the significance attached to them. Lobular carcinoma is more likely to be larger, lymph node positive and estrogen positive then invasive ductal. A study in the ann surg oncol. 2010 jul;17(7):1862-9. Epub 2010 feb 17 suggests that invasive lobular carcinoma has a better prognosis stage for stage than invasive ductal carcinoma. ...Read more

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I need to know what is lobular carcinoma?

I need to know what is lobular carcinoma?

Type of breast ca: About 15% of breast cancers are the lobular type. They develop from the milk-producing lobules in the breast. They are usually estrogen receptor positive and they respond well to hormone therapies like tamoxifen. ...Read more

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How is invasive lobular carcinoma (ilc) usually diagnosed?

How is invasive lobular carcinoma (ilc) usually diagnosed?

Biopsy: The only way to make a diagnosis of ilc is by biopsy (usually needle biopsy). The problem with ilc is that it often does not show up on a mammogram or sonogram until it is large or a lump can be felt. That is why the diagnosis of ilc is often made later than other types of breast cancer. ...Read more

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I have invasive lobular carcinoma. What are my chances of complete recovery?

I have invasive lobular carcinoma. What are my chances of complete recovery?

Good: Lobular breast cancer is more frequently multifocal and bilateral than ductal carcinoma. However, with mastectomy (lumpectomy may not be sufficient) and sentinel lymph node biopsy, with follow-up hormone therapy and/or radiation should yield a good outcome, depending on the grade and stage of the cancer. Stage is most important, along with hormone receptor status. ...Read more

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Is invasive lobular carcinoma the same as invasive ductal carcinoma?

Different: Lobular carcinoma is less common and often does not form a lump. Please see these sites for more information. http://www.mayoclinic.com/health/invasive-lobular-carcinoma/ds01063 http://www.Mayoclinic.Com/health/breast-cancer/ds00328. ...Read more

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What is the survival rate of patients with invasive lobular carcinoma?

What is the survival rate of patients with invasive lobular carcinoma?

Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, direct extension to the skin or chest wall muscles, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. ...Read more

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Can someone with lobular carcinoma breast feed?

Can someone with lobular carcinoma breast feed?

After treatment: I trust that you have been treated for the carcinoma. If you have been treated it is okay to breast feed. ...Read more

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Can women with invasive lobular carcinoma breast feed their babies?

Yes: Breast cancer cannot be transmitted to your baby in breast milk you are better off to treat your cancer sooner rather than continuing to breast feed your baby. ...Read more

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Is it safe for a women with invasive lobular carcinoma breast feed?

Yes: I trust that you were treated for breast carcinoma and are now blessed with a child. Cancer is not transmitted through milk, though some other diseases, such as HIV can be. ...Read more

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I have invasive lobular carcinoma, stage 2b, grade 2, spread to 1 lymph-node. Estrogen + , her2 - should I consider genetic testing?

I have invasive lobular carcinoma, stage 2b, grade 2, spread to 1 lymph-node. Estrogen + , her2 - should I consider genetic testing?

Yes, please: Breast cancer at age 33 meets criteria for brca testing. The results may significantly impact one's surgical treatment decision (best to do before radiation therapy, since this would be unnecessary if one opts for mastectomy). That said, without any other risk factors, the statistical probability of being brca (+) is not that high. Please see a genetic counselor. ...Read more

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The drug is taxotere (docetaxel) and cyclophosphamide used in chemo due to early stage of invasive lobular carcinoma does side effect cause insomia , depression?

The drug is taxotere (docetaxel) and cyclophosphamide used in chemo due to early stage of invasive lobular carcinoma does side effect cause insomia , depression?

Chemo and cancer: Dealing with cancer and its treatment is not something easy to do in many cases. Not only it is affecting your physical condition, emotionally, you can also develop anxiety, depressed mood, depression etc through out the battle. The chemo themselves do not give you insomnia. However, steroids are given prior to chemo, and this can cause insomnia. Depression/anxiety cause insomnia too. ...Read more

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Whats the difference between carcinoma in situ and cin?

Since no one has: Answered in a week, i think it is because like me, they do not know what cin is. We all know that carcinoma in situ means the cancer is superficial, not invading through a structure, and generally conveying risk of becoming invasive cancer. This is most prevalently used in breast cancer. However, i cannot contrast to cin. I do not know what that is. ...Read more

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I was wondering are precancerious polyps carcinoma in situ?

I was wondering are precancerious polyps carcinoma in situ?

Not necessarily: Most precancerous polyps of the colon are considered adenomas. These can progress to contain areas of severe dysplasia and/or carcinoma in situ which mean that they are one step closer to becoming malignant. ...Read more

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I was diagnosed with anal carcinoma in situ twice what are the chances that it will reoccure?

Unfortunately High: Anal carcinoma in situ is a rare pre-cancerous condition that often will recur. It may be associated with HIV and is usually directly caused by hpv. Sometimes close observation by anal "mapping" every 3-4 months is enough with small operations to remove any new lesions as needed. In other instances, treatment with imiquimod, laser therapy or radiation therapy might be recommended. ...Read more

Dr. Tanya Russo
43 doctors shared insights

Carcinoma In Situ (Definition)

Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this ...Read more


In Situ (Definition)

Means localosed in place. Medical terms is for carcinoma "localized and did not spread out" it is really description of precancerous condition with bad name that disturbs many patients. Carcinoma in situ is not a killer. If left untreated will develop into invasive cancer ...Read more