Doctor insights on:
Lobular Carcinoma In Situ In Children
Also called lobular: Neoplasia...It forecasts that you will develop a breast cancer in either breast. Some used to do "mirror" biopsies. Others contemplate bilateral mastectomy. Lcis is a risk not a cancer, but the lobular invasive cancer can pose detection problems. Discuss this with a breast cancer team. I would watch very carefully. Lobular cancer makes up only 15% of invasive cancer. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Yes BUT: We need to consider that this is probably lobular "neoplasia" vs. Cis. That being said we still feel this is marker of increased cancer risk. We shouldn't neglect putting together fam history, other risk factors, limitations & risks in imaging, etc before discounting antihormonal therapy and rarely surgery. Many do choose close follow-up. Natural treatments may be incorporated with sufficient data. ...Read more
What are the causes of breast and arm pain after having biopsy with lobular carcinoma in situ diagnosis?
LCIS: Lobular-carcinoma-in-situ (lcis) is a microscopic finding on breast biopsy that is associated with an increased risk of breast cancer in either breast of those affected. It is silent in that it causes no symptoms. Therefore, your breast & arm pain is unrelated to the diagnosis. Perhaps the pain is related to the biopsy procedure itself. If so, it should resolve pretty quickly. ...Read more
Biopsy: The only way to make a diagnosis of ilc is by biopsy (usually needle biopsy). The problem with ilc is that it often does not show up on a mammogram or sonogram until it is large or a lump can be felt. That is why the diagnosis of ilc is often made later than other types of breast cancer. ...Read more
Good: Lobular breast cancer is more frequently multifocal and bilateral than ductal carcinoma. However, with mastectomy (lumpectomy may not be sufficient) and sentinel lymph node biopsy, with follow-up hormone therapy and/or radiation should yield a good outcome, depending on the grade and stage of the cancer. Stage is most important, along with hormone receptor status. ...Read more
Is mastectomy good for an invasive & in situ lobular carcinoma, stage 1b, sbr grade 2, 8 mm in size with good margins except anterior margin 1.5mm?
Concern: The 1.5mm margin anteriorly is the only margin that gives me concern. For patients undergoing lumpectomy, obtaining at least a 2mm margin is associated with a decreased risk of recurrence. It would not be usual practice to take you back to surgery for a re-excision of this margin, however. ...Read more
No: Although both are breast cancers they are different in the significance attached to them. Lobular carcinoma is more likely to be larger, lymph node positive and estrogen positive then invasive ductal. A study in the ann surg oncol. 2010 jul;17 (7):1862-9. Epub 2010 feb 17 suggests that invasive lobular carcinoma has a better prognosis stage for stage than invasive ductal carcinoma. ...Read more
Lobular carcinoma is less common and often does not form a lump. Please see these sites for more information.
http://www. Mayoclinic. Com/health/invasive-lobular-carcinoma/ds01063
http://www. Mayoclinic. Com/health/breast-cancer/ds00328. ...Read more
Stage-Dependent: Breast cancers are staged based upon the size of the cancer, lymph node or distant organ involvement, direct extension to the skin or chest wall muscles, and unique molecular features of the tumor. Published rates of 5-yr survival (http://www. Cancer. Org/cancer/breastcancer/detailedguide/breast-cancer-survival-by-stage) vary quite a bit based on these variables, between 15%-93%. ...Read more
What is the survival rate for stage 3 invasive lobular carcinoma? Possibly has been there for 3-4 years undetected.
5 year: Survival rate is approximately 70%.Get a more detailed answer ›
Breast cancer cannot be transmitted to your baby in breast milk
you are better off to treat your cancer sooner rather than continuing to breast feed your baby. ...Read more
Possible: There is no biologic reason to not have the lesions you described. ...Read more
I have invasive lobular carcinoma, stage 2b, grade 2, spread to 1 lymph-node. Estrogen +, her2 - should I consider genetic testing?
Yes, please: Breast cancer at age 33 meets criteria for brca testing. The results may significantly impact one's surgical treatment decision (best to do before radiation therapy, since this would be unnecessary if one opts for mastectomy). That said, without any other risk factors, the statistical probability of being brca (+) is not that high. Please see a genetic counselor. ...Read more
The drug is taxotere (docetaxel) and cyclophosphamide used in chemo due to early stage of invasive lobular carcinoma does side effect cause insomia, depression?
Chemo and cancer: Dealing with cancer and its treatment is not something easy to do in many cases. Not only it is affecting your physical condition, emotionally, you can also develop anxiety, depressed mood, depression etc through out the battle. The chemo themselves do not give you insomnia. However, steroids are given prior to chemo, and this can cause insomnia. Depression/anxiety cause insomnia too. ...Read more
Depends: Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this for a cervix lesion. ...Read more
Since no one has: Answered in a week, I think it is because like me, they do not know what cin is. We all know that carcinoma in situ means the cancer is superficial, not invading through a structure, and generally conveying risk of becoming invasive cancer. This is most prevalently used in breast cancer. However, I cannot contrast to cin. I do not know what that is. ...Read more
Unfortunately High: Anal carcinoma in situ is a rare pre-cancerous condition that often will recur. It may be associated with HIV and is usually directly caused by hpv. Sometimes close observation by anal "mapping" every 3-4 months is enough with small operations to remove any new lesions as needed. In other instances, treatment with imiquimod, laser therapy or radiation therapy might be recommended. ...Read more
Good question: And difficult to tell sometimes. The most straightforward way to put it is that a benign neoplasm will never turn into an invasive malignancy within your lifetime. Cis will eventually turn into one. But, because we don't live forever, cis might not turn into a malignancy during one's lifetime anyway. Pathologists can usually, but not always, tell the difference by microscopic cell exam. ...Read more
"in place": Ductal carcinoma in situ (DCIS) of the breast is a breast cancer which has started in the ducts of milk glands (as most breast cancers do) but not yet invaded beyond that into the fat of the breast. Untreated, it has a high likelihood of becoming invasive breast cancer, a potentially fatal disease. Treated DCIS has a high cure rate. Some with DCIS benefit from taking med to prevent 2nd cancer. ...Read more
Not all invasive: Cancers start in situ, and not all in situ cancers ultimately invade...But a lot do. So, there is no timetable of when that you can rely on. It is reasonable to take care of in situ when you find it, rather than trust an unreliable actor to behave itself the way you might like. ...Read more
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. With time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
INVASIVE or DCIS?: These terms are incongruous: dcis is, by definition, breast cancer that has not "broken out" of the ducts and entered the adjacent supportive tissue of the breast; invasive, or infiltrating ductal cancer, by definition, has. The treatment of these 2 diseases is quite different since there is a risk of systemic disease with the latter. Please clarify, thanks. ...Read more
I was diagnosed with severe displasia/carcinoma in situ (cin3).I am having a lot of pelvic pain is that normal?
Cervical dysplasia: Cin iii does not cause pain. If there is pain, there is another issue. ...Read more
Can you have low grade superficial bladder cancer then in 6 months develope carcinoma in situ if the bladder. Is that a recurrance or a new cancer?
Yes and no: Bladder cancers arises multifocally. By the time that the first cancer appears, the entire epithelium covering the bladder already bears mutations, and new cancers begin popping up in various places. They are part of the same underlying process although they are individual cancers. This is a tricky concept. I'm glad your disease was detected and hope that you'll get a good outcome. ...Read more
Genetic mutations: This is mostly a random event. There's a natural instability in the human genome even if you are never exposed to anything that's obviously a mutagen. The other factors that place you at risk for breast cancer (nulliparity, brca1 / brca2 mutations, etc.) are risk factors here, but no woman (and actually no man either) is immune. ...Read more
Biopsy: A biopsy with review by pathology is how it is distinguished. ...Read more
Should be fine: You will need to have a surgery to remove the breast carcinoma in situ. In addition to that -if you have a lumpectomy- you would need to get an a radiation therapy following the surgery to reduce risk for recurrence and tamoxifen would be recommended to take for 5 years. You should have a mammogram yearly basis and self breast examination is recommended. Prognosis is good as it is not invasive. ...Read more
Good morning. I made a Conization in the cervix in 2008, because I had a carcinoma in situ. I wonder if it is safe to use tampons or menstrual cup?
Safe, and get PAP:
You should continue getting PAP smears, as recommended by your doctor. Tampons or cup is safe.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more
Depends on where this diagnosis was made. Is a non-invasive disease. Ductal carcinoma in situ of the breast is treated with lumpectomy and sometimes hormone therapy & radiation. Lobular carcinoma in situ of breast is treated as a benign pre-cancerous lesion. Cancer in situ of the colon treated as an early cancer with surgery. Gynecologist can answer this ...Read more
Means localosed in place. Medical terms is for carcinoma "localized and did not spread out" it is really description of precancerous condition with bad name that disturbs many patients. Carcinoma in situ is not a killer. If left untreated will develop into invasive cancer ...Read more