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Doctor insights on: Liver Transplants Porphyria

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Dr. Amrita Dosanjh
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


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Can an abnormal liver test result be a sign of porphyria?

More common causes: Porphyria can cause abnormal liver tests, but there are far more common causes of liver abnormality, e.g., alcohol. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002188/. ...Read more

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Are animal livers used in human transplants?

Are animal livers used in human transplants?

Not successfully: Animal organs have been used - in experimental circumstances - for a variety of human transplants, without long-term success. Remaining obstacles of rejection are major. When a winning strategy is developed, you will know because we will suddenly be able to address the organ shortage. We can use animal heart valves (usually pig) because they are treated + no longer stimulate an immune response. ...Read more

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I'm wondering how successful are liver transplants?

Can be life-saving.: Liver transplants, like most organ transplants, are much more successful these days than they have been in the past. Liver transplantation is only recommended for life-threatening diseases of the liver, so if recommended, should certainly be considered. It is difficult to give a percentage, because it varies depending on the reason for the transplant in the first place. Good luck. ...Read more

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When might a liver need a transplant?

When might a liver need a transplant?

Does not function : When the liver permanently ceases to function. Can result from congenital diseases, infections, bile duct diseases, tumors, etc. The liver is needed to remove drugs and other waste products, makes bile, proteins, and is responsible for the clotting factors. A blocked liver can cause fluid retention (ascites) and result in jaundice (yellow skin) and/or encephalopathy. ...Read more

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Can babies receive liver transplants?

Yes: Even very small babies can undergo liver transplantion, though success rates increase for infants who weigh more than 10 kg. ...Read more

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How long will a transplanted liver last?

A long time: Potentially a transplanted liver can last decades, a lifetime. Some diseases, such as hepatitis c, can recur with a vengeance. But i often tell patients that if they make it the 1st yr, their bungee cord may break, their parachute may not open, but they won't die of liver disease. ...Read more

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How long does a transplanted liver last in recipients?

Several variables: It can vary based on the cause of liver failure, source of the liver, and the condition of the recipient at the time of transplant. Overall about 70% of grafts are functioning at 5 years and 50% are functioning at 10 years after the trasplant. ...Read more

Dr. Jeffrey Satinover
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


Dr. Aletha Tippett
89 doctors shared insights

Porphyria (Definition)

The porphyrias are metabolic disorders caused by abnormalities in the synthesis of heme, the portion of hemoglobin which carries the iron inside red blood cells. The manifestations of porphyria vary considerably depending on the mutation involved, ranging from light sensitivity to liver failure to nerve damage to bouts of terrible pain. Special testing is required to ...Read more