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Doctor insights on: Liver Transplants Porphyria

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Dr. Tiffanie Noonan
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


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Can an abnormal liver test result be a sign of porphyria?

Can an abnormal liver test result be a sign of porphyria?

More common causes: Porphyria can cause abnormal liver tests, but there are far more common causes of liver abnormality, e.g., alcohol. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002188/. ...Read more

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Could porphyria explain my burning sensation in the abdomen and severe back pain?

Could porphyria explain my burning sensation in the abdomen and severe back pain?

Yes: Acute intermittent pophyria commonly causes abdominal pain, and has been known to cause other pains. If your pains persist, you should see your docot in case there is another cause. ...Read more

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Are animal livers used in human transplants?

Are animal livers used in human transplants?

Not successfully: Animal organs have been used - in experimental circumstances - for a variety of human transplants, without long-term success. Remaining obstacles of rejection are major. When a winning strategy is developed, you will know because we will suddenly be able to address the organ shortage. We can use animal heart valves (usually pig) because they are treated + no longer stimulate an immune response. ...Read more

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I'm wondering how successful are liver transplants?

Can be life-saving.: Liver transplants, like most organ transplants, are much more successful these days than they have been in the past. Liver transplantation is only recommended for life-threatening diseases of the liver, so if recommended, should certainly be considered. It is difficult to give a percentage, because it varies depending on the reason for the transplant in the first place. Good luck. ...Read more

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When might a liver need a transplant?

When might a liver need a transplant?

Does not function : When the liver permanently ceases to function. Can result from congenital diseases, infections, bile duct diseases, tumors, etc. The liver is needed to remove drugs and other waste products, makes bile, proteins, and is responsible for the clotting factors. A blocked liver can cause fluid retention (ascites) and result in jaundice (yellow skin) and/or encephalopathy. ...Read more

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Can babies receive liver transplants?

Yes: Even very small babies can undergo liver transplantion, though success rates increase for infants who weigh more than 10 kg. ...Read more

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How long will a transplanted liver last?

A long time: Potentially a transplanted liver can last decades, a lifetime. Some diseases, such as hepatitis c, can recur with a vengeance. But i often tell patients that if they make it the 1st yr, their bungee cord may break, their parachute may not open, but they won't die of liver disease. ...Read more

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How long does a transplanted liver last in recipients?

Several variables: It can vary based on the cause of liver failure, source of the liver, and the condition of the recipient at the time of transplant. Overall about 70% of grafts are functioning at 5 years and 50% are functioning at 10 years after the trasplant. ...Read more

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How does someone get on the transplant list for a liver?

How does someone get on the transplant list for a liver?

Find a center: First you must be evaluated by a transplant center. A referral can be made by your primary doctor or hepatologist. You could also contact them directly. There they will determine if you actually need one and if you qualify medically. You must be sick enough to need a new liver but healthy enough to survive the surgery. ...Read more

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What's the extended criteria donor category for liver transplants?

What's the extended criteria donor category for liver transplants?

Riskier criteria: Too few organs to save the lives of all who need a liver forces us to offer organs that we might not consider acceptable. The "extension" of the criteria range may be based on age (a donor > 70 years?), social risk (did the donor use drugs recently?) or other issue. If we don't use an organ that would have been reasonable, another person dies. Informed consent is the key. Speak with your team. ...Read more

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Is there any other option then transplantation for shrunken liver?

Is there any other option then transplantation for shrunken liver?

No if from cirrhosis: Cirrhosis, or scarring of the liver, is probably what made it shrink. Once the liver functions begin to fail - poor synthesis of proteins and poor processing of metabolic byproducts - a replacement liver will be required for long term survival. Unfortunately, today there are no other options. ...Read more

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What percentage of wilson's disease patients need liver transplants? 

What percentage of wilson's disease patients need liver transplants? 

Wilson and transplan: Roughly , about 30 % of patients. These are patient unable to tolerated the quelation therapy and develope neuropsyquiatric symptoms . Hope this help. ...Read more

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Why do people need liver transplants?

Liver failure: There are a number of conditions that lead to shutdown of the liver. Some you can be born with, others are anatomic problems, some are infections and still others are toxins. Regardless of the cause when the liver doesn't work our bodies don't work. The only cure for total liver failure is transplantation. ...Read more

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Do liver transplants require an entire liver?

Do liver transplants require an entire liver?

Not necessarily. : Not necessarily. Generally, a whole liver is transplanted, but it's possible to transplant a portion of liver. For example, if the recipient is small-sized an entire liver may be too big. Also, if the liver donor is alive, clearly only a portion of liver can be taken (usually about half). ...Read more

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How long to people live with liver transplants?

How long to people live with liver transplants?

Unknown: The unfortunate but fundamental truth while dealing with this question is that there is no final and definitive answer. This unavailability of an answer can be attributed to a variety of factors. One of them being that the whole phenomenon of liver transplantation is too recent an endeavor in medical science and hence, research and studies are still being held to understand the possible life expec. ...Read more

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What complications are most common with liver transplants?

What complications are most common with liver transplants?

Liver transplant: The most common complications of liver transplants are infection, rejection of the new liver, and disease recurrence. Any of these can result in severe problems or even the need for a second transplant. Hope that helps. ...Read more

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Do women who have had liver transplants have difficulty bearing children?

Talk to MD: The person with a liver transplant is at increased risk during pregnancy, partly due to the immuno-supression drugs that they are taking. A decision to enter pregnancy should be undertaken after a careful discussion with your transplant team. Good luck. ...Read more

Dr. Eric Weisman
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


Dr. Aletha Tippett
91 doctors shared insights

Porphyria (Definition)

Metabolic disorders caused by abnormalities in the synthesis of heme, the portion of hemoglobin which carries the iron inside red blood cells. Symptoms can range from light sensitivity to liver failure to nerve damage to bouts of terrible pain.Special testing is required to ...Read more