Doctor insights on:
Liver Failure Due To Pancreatic Cancer
Hi, this is probably me being over concerned but recently I've noticed 2 or 3 yellow patches of skin on my legs and its making me nervous. Liver failure but I don't drink excessively. Pancreatic cancer? Should I be worried?
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Short answer: No:
Most often if a malignant mass presses on the ductal system of liver or panc. (see picture), it can cause abn. Blood enzymes. If the mass is small and ducts drain, routine enzymes are usually normal.
Gilbert Syndrome, a genetic abn. Of up to 7% of folks, has the significance like your fingerprints, and is discussed nicely in: http://ghr. Nlm. Nih. Gov/condition/gilbert-syndrome ...Read more
Panc elastase test shows insufficiency. Have fatty liver. Is pei cause of fatty liver? Is there connection between fatty liver and pancreatic cancer?
No, just description: Like most dx, just a label for a pattern, as judged by whatever metrics. Yes, there is observed relation between fatty liver ; developing liver cancer. Fatty liver most commonly due to persistent low-fat, hi-carb (i.e. All sugars, simple ; complex) foods. Liver, to protect rest of body from ↑sugar (toxic), converts sugars into triglyceride fats. If can't export into external fat, then fatty liver. ...Read more
Chemotherapy: Generally chemotherapy. If the cancer has spread to the liver, it probably has also spread to other organs in amounts too small to be seen by even the highest quality scans. Since chemo enters the blood stream, that's why this is the best treatment. After chemo, if there is only 1 or 2 liver spots, sometimes these can ablated (radiation or heat probes). ...Read more
Surgery: With favorable tumors of either the liver or the pancreas, surgery, often combined with chemo may be curative. Both of these types of cancer and the surgical treatments for them are highly specialized and should be performed by a surgeon with experience and training in hepatobiliary surgery. ...Read more
My son has pancreatic cancer and it has matastized to the liver. That tumor is small and the cancer is no where else. Why not remove the liver tumor?
My son has pancreatic cancer which is also in the liver. The liver tumor is small. They found no other places with cancer. Why not remove liver tumor?
Depends: It really depends on type of cancer. Adenocarcinoma is not resectable once outside the pancreas because there are other areas that u can't see yet. If it is neuroendocrine tumor then surgery is an option. Also liver lesion needs to be biopsied or pet positive to reliably say that there is cancer there. Get another opinion. ...Read more
Can clinical trials be of any benefit for a person with pancreatic cancer and extensive mets to the liver?
Pancreatic cancer: "Benefit" in such situation depends on patient / family's expectation from treatment that is being offered. Seems like you know that it is not a definitive treatment. ...Read more
Can the pancreatic cancer get treated after there was a mass between it and the liver which grows quickly? What's percentage of patient live?
Lymph node: I guessing that you are describing cancer that spread to a lymph node that is located between the pancreas and the liver. If this is the only place the cancer has spread, and the pancreas cancer is otherwise fully removed, the average survival is about 2 years if you get chemotherapy after the operation. Talk to your surgeon and oncologist for more details. ...Read more
If you have pancreatic cancer, do you always get jaundice? Also is there a link between P/C and fatty liver? Both found by U/S at same time
While jaundice,: Result of obstruction to bile ducts, is very common in pancreatic cancer, especially in more advanced disease, it is not always present. I would think the majority of cases, though, over 50%, would reveal themselves (present) with obstructive symptoms: jaundice, dark urine, pale stool, itching. Fatty liver does not cause pancreatic cancer but, you are correct, can be discovered with an ultrasound. ...Read more
This is not good...:
Pancreas cancer is very difficult cancer to treat, mostly because when found, it has already spread to many other areas -- adjacent organs, lymph nodes, liver, lungs, or brain. That makes "early" treatment impossible.
Fortunately new medications that can kill pancreas cancer cells (depending on the kind that one has) have helped many people live longer & better, but it is still a bad cancer. ...Read more
If someone has pancreatic cancer and an MRI was done that showed a new tumor (liver) does this mean it is always cancerous? Does a biopsy make sense?
Maybe: Every lesion seen doesn't mean its cancer. A biopsy would make sense if you would do something different with either a positive, negative, or non-diagnostic result. If there would be nothing different done in terms if treatment, life planning, etc., twgardless of the result, them don't do it. Hope this helps! ...Read more
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more
My dad have pancreatic cancer that has spread to his liver. He took chemo and the doctor stopped it because it did not help. How long will live?
No sure answer:
Pancreatic ca, is very hard to treat, and frequently painful.
Help him stay well nourished.
See that he gets the best pain control he can.
Be realistic on stage and tx benefits. ...Read more
My mom has pancreatic cancer & just learned it spread to her liver. She is in the hospital w/jaundice, chill, her biliruban is 3.9. What is happening?
Sorry to hear this: First off I wish your mother and family the best. Also, your best bet is to ask this very important question to her oncologist and/or covering doctor. They have access to more information than you can readily provide us here and it will be more meaningful/accurate. ...Read more
My mom has pancreatic cancer that started spreading to liver. Her oncologist not sure if continuing (gemzar) chemo would benefit her. Any suggestions?
Probably not: Your question implied that she developed liver metastasis while on gemzar (gemcitabine). If so, it is not llikely that continuing Gemzar (gemcitabine) alone will be helpful. She should speak with her oncologist about newer and more promising chemotherapy regimens such as adding nab-paclitaxel or trying folfirinox. Recent studies have shown encouraging results! ...Read more
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
A condition characterized by failure of the liver to perform its functions, which are vital for life. Liver has many functions: cleaning the body of toxins, processing food, producing proteins and blood clotting factors, modulating blood glucose. Failure can be seen: bleeding, fluid accumulation, yellow skin, no energy, confusion. Liver failure occurs acutely (rapid) ...Read more
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