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Doctor insights on: Liver Cancer Hepatocellular Carcinoma

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Can you tell me about liver cancer (hepatocellular carcinoma) and used nexavar (sorafenib)?

Can you tell me about liver cancer (hepatocellular carcinoma) and used nexavar (sorafenib)?

Used for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more

Dr. Barry Rosen
4,478 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is it true that hepatocellular carcinoma liver disease or liver cancer?

Is it true that hepatocellular carcinoma liver disease or liver cancer?

Liver cancer: Heaptocellular carcinoma is a primary cancer of the liver. Hcc is most commonly associated with underlying liver disease, such as viral hepatitis, but can be associated with other conditions of the liver that cause scarring or cirrhosis. Although hcc can also occur in otherwise normal liver substance, this is rare (only 10% of cases). ...Read more

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Tell me more about fibrolamellar hepatocellular carcinoma - a rare form of liver cancer?

Tell me more about fibrolamellar hepatocellular carcinoma - a rare form of liver cancer?

Better prognosis: Fibrolamellar hepatocellular carcinoma has better prognosis than usual liver cancers. The diagnosis is made by examining the tissue by a pathologist. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmed/16475212. ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Chart reads breast cancer (HCC) (worded exactly). What does the HCC mean? Is it only Hepatocellular carcinoma?

Chart reads breast cancer (HCC) (worded exactly). What does the HCC mean? Is it only Hepatocellular carcinoma?

I don't know: It is probably a local abbreviation that means something; was it perhaps diagnosed at Harvard Cancer Center? As eager as we are to answer, this is the wrong place to bring a question like this. ...Read more

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What is the best treatment for hepatocellular carcinoma besides liver transplantation?

What is the best treatment for hepatocellular carcinoma besides liver transplantation?

Resection: Licer resection is the next best treatment, tumor ablation would be next followed up by liver directed chemotherapy and finally systemic (total body) chemotherapy. ...Read more

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Can some survive hepatocellular carcinoma?

Can some survive hepatocellular carcinoma?

Yes: When i was in med school, it was almost always fatal. Now we're often curing them through early detection and especially teamwork by radiologists and surgeons. ...Read more

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Whats treatment for small early hepatocellular carcinoma?

Hcc: Liver transplant will take out the tumor and also replace the liver that is at risk for getting new hcc. If the patient is not a candidate for transplant then resection of the tumor would be the best treatment for small hcc. If that is not possible ablation would give the best durable therapy for locoregional treatment of a small hcc. ...Read more

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How is the prognosis and treatment for early hepatocellular carcinoma?

Good: Depending on the underlying liver disease, early stage hcc is curable. Unfortunately, the liklihood of additional tumors popping up in a diseased liver is also high. There are surveillance programs around the country and world for high risk patients. ...Read more

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What are the chances of hepatocellular carcinoma if you have chronic hepatitis b?

What are the chances of hepatocellular carcinoma if you have chronic hepatitis b?

Increased: Chronic hepatitis virus can increase a person's risk for developing hepatocellular carcinoma. It does not mean that everyone with hepatitis gets cancer. Cirrhosis and other liver damage is more common from the hepatitis virus. ...Read more

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What are the chances of getting hepatocellular carcinoma with the chronic hepatitis b?

What are the chances of getting hepatocellular carcinoma with the chronic hepatitis b?

Depends when the : Infection is acquired. If the infection was acquired in infancy there is about a 25% risk of liver cancer. See this site for more info. http://www.who.int/mediacentre/factsheets/fs204/en/. ...Read more

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What are the chances of hepatocellular carcinoma with chronic hepatitis b? Is this likely?

What are the chances of hepatocellular carcinoma with chronic hepatitis b? Is this likely?

Possibly: People who are infected with hepatitis B virus (HBV) may develop a chronic infection that can lead to cirrhosis. The damage that results increases the risk of liver cancer (hepatocellular carcinoma). The risk is greater for people who have chronic HBV infection than for the general population and may be helped by vaccination. ...Read more

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Is it possible to survive hepatocellular carcinoma?

Is it possible to survive hepatocellular carcinoma?

Yes: The factors that favor a good outcome are small tumor size, no infections with Hepatitis B and C, being older than 5, good liver function (no liver failure), no inflammation (normal CRP blood test), no spread of cancer, surgery intended to "cure" the cancer, size of tumor ...Read more

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How often have people survived hepatocellular carcinoma?

How often have people survived hepatocellular carcinoma?

Depends on therapy: Its really therapy dependent. Most hcc are related to cirrhosis, usually extensive and multiple and not amenable to therapy. Only early hcc can be amenable to resection and or liver transplant. Transplant is curative, as can be resection in the absence of cirrhosis. ...Read more

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What is the definition or description of: Hepatocellular carcinoma?

What is the definition or description of: Hepatocellular carcinoma?

A Cancer of Liver: Hepatocellular carcinoma(HCC) is a Cancer arising from the Liver. It often occurs in in people who have a chronically damaged liver due to infection with Hepatitis B or hepatitis C Virus or it can be due to use of excessive alcoho, drinking that leads to Cirrhosis which then makes you more prone to develop Liver Cancer(HCC). ...Read more

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I've developed hepatocellular carcinoma. What should I be watching out for in the future?

I've developed hepatocellular carcinoma. What should I be watching out for in the future?

The best results are: From surgery, and that depends on the tumors location in relation to the big blood vessel, the portal vein, and the viability of the liver not involved with the tumor itself. If your tumor is not resectable, there are new but expensive medicines that cause response and shrinkage. If the tumor grows or cannot be stopped, the liver will fail. I see some with bony metastasis. Best wishes. ...Read more

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What is the average lifespan of hepatocellular carcinoma?

Complicated: The answer depends on several factors including the underlying liver disease, the size number and pattern of spread within the liver, and any other medical problems that the patient has that will effect their ability to tolerate therapy. There are several treatments available for hcc. ...Read more

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Dr. Barry Rosen
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


Dr. Andrew Seibert
7 doctors shared insights

Primary Carcinoma (Definition)

Primary carcinomas arise within the organ that they are detected in. They arise from primary mucosal tissues in which they grow. When examined at a molecular level all arise in a field effect with one site growing and suppressing other sites. They can be detected when the oncofetal protein is expressed and the cell still looks normal. When MMTV virus enters breast duct ...Read more