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Doctor insights on: List Demyelinating Diseases

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What is neurological disease-demyelinating disease? What are its symtoms?

What is neurological disease-demyelinating disease? What are its symtoms?

Demyelinating Dx: Demyelinating disease causes weakness and sensory loss. Myelin insulates the nerves of the central and peripheral nervous system. Illnesses that cause damage to myelin are called demyelinating diseases. Examples are multiple sclerosis and CIDP or chronic inflammatory demyelinating polyradiculoneuropathy. ...Read more

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Is tourettes a demyelinating disease?

Is tourettes a demyelinating disease?

No: Tourette's is not classified with diseases such as multiple sclerosis, and is a very different disorder. Such problems as visual loss, weakness, imbalance or incoordination would not be part of tourette's. Nice that we have effective ms meds these days, and many new meds work very well for tourette's. ...Read more

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Which other diseases is associated with demyelinating disease besides ms?

Which other diseases is associated with demyelinating disease besides ms?

See below: Some hereditary problems called leukodystrophies, association with toxins, like glue-sniffing, medication reactions, such as anti-cancer drugs. And, of course, many peripheral nerve problems which can demyelination of distal nerves, such as chronic inflammatory demyelinating radiculoneuropathy. ...Read more

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I need to know what is neurological disease-demyelinating disease? What are its symtoms?

I need to know what is neurological disease-demyelinating disease? What are its symtoms?

Demyelinating diseas: Refers to loss of myelin in the central/peripheral nervous system. In the CNS the most common cause is multiple sclerosis (ms). In the pns the most common cause is diabetes. Symptoms for CNS demyelination depend upon where the lesion is located- visual, motor, sensory...
In the pns, symptoms for demyelination include paresthesias, numbness, burning, weakness and usually starting in the legs. ...Read more

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Could strong antipsychotics cause neurons damage and result in demyelinating disease?

Could strong antipsychotics cause neurons damage and result in demyelinating disease?

Antipsychotics: Demyelinating disease is generally autoimmune in nature -- different from the effects of antipsychotic medications. In fact some research indicates that quetiapine may protect against demyelination. http://www.plosone.org/article/info%3adoi%2f10.1371%2fjournal.pone.0042746 nevertheless, long-term use of some antipsychotic agents can affect neuronal function -- just differently. ...Read more

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What does mixed atonal/demyelinating poly neuropathy mean and what are diseases associated with it?

What does mixed atonal/demyelinating poly neuropathy mean and what are diseases associated with it?

CIDP-GUILLIAIN BARRE: ATONAL MEANING DYING BACK.IT CAN EFFECT POLY NEUROPATHY DUE TO DEMYELINATION. IT IS CIDP-GUILLIAN BARRE SYNDROME.THERE ARE CASES OF IT IN MANY COUNTRIES.
IT CAN DEVELOP AFTER PREVENTIVE SHOT OF INJECTION FOR INFLUENZA.
OCCASIONALLY IT CAN BE FATAL, IF IT INVOLVES INTERCOSTAL MUSCLES. ...Read more

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What does mixed axonal/demyelinating poly neuropathy mean and what are diseases associated with it?

What does mixed axonal/demyelinating poly neuropathy mean and what are diseases associated with it?

Neuropathy: Neuropathies are normally differentiated between axonal and or demyelinating. Axonal is nerve fibers are damaged and demyelinating is covering of the nerves are damaged. All neuropathies may be mixed such as in Guillain-Barré, but most neuropathies are related to hypothyroidism, diabetes, vitamin B12 deficiency and/or alcoholic. A mixed pattern does not provide diagnostic help. Hope that helps ...Read more

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Is progressive supranuclear palsy a demyelinating disease?

Is progressive supranuclear palsy a demyelinating disease?

PSP: Progressive supranuclear palsy: the disorder's long name indicates that the disease begins slowly and continues to get worse (progressive), and causes weakness (palsy) by damaging certain parts of the brain above pea-sized structures called nuclei that control eye movements (supranuclear).

It is central; demyelinating conditions occur in the peripheral nervous system. ...Read more

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What can cause brain demyelination besides a demyelinating disease?

What can cause brain demyelination besides a demyelinating disease?

Several: There are hereditary problems called leukodystrophies, toxins such as glue-sniffing can damage brain myelin, paraneoplastic events associated with cancers can have some effect, and of course ms as the best known cause. But sometimes, other disorders seem similar and can masquerade. ...Read more

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Is there a demyelinating disease other than MS which is also caused by an autoimmune disease?

Is there a demyelinating disease other than MS which is also caused by an autoimmune disease?

Immune demyelination: Yes. The Best discussion go to uptodate.com
I recommend using only uptodate to find medical info on web. ...Read more

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MRI=enhancingT2hyperintense foci in both cerebellar regions may represent demyelinating disease. Other less likely metastasis or any infiltrative?

MRI=enhancingT2hyperintense foci in both cerebellar regions may represent demyelinating disease. Other less likely metastasis or any infiltrative?

Complex question.: We will need to discuss your symptoms to figure out the significance of any such "findings" on the MRI. This isn't the forum to discuss- use HealthTap Prime or talk to your doctor / neurologist. In the mean time, obtain the MRI pictures & upload the pictures + report onto your computer. A metastasis in BOTH cerebellums, symmetrically, is ridiculously improbable. Can't say much more here. Good luck ...Read more

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MRI showed moderate supratenatorial white matter disease suspicious of demyelinating process. Multiple nodular foci periventricular Could you explain?

MRI showed moderate supratenatorial white matter disease suspicious of demyelinating process. Multiple nodular foci periventricular Could you explain?

Concern for MS, But: Phyllis, talk to the doctor who ordered the MRI, since he/she can interpret the MRI in the context of the symptoms that brought you to the clinic. In some cases, periventricular white matter lesions are the result of migraines, old head trauma, neuron migration issues, or MS. It is hard to know from just a description of the MRI which is the cause. Good Luck and Stay Healthy! ...Read more

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I have a demyelinating brain disease confirmed by mri. What precautions or life changes should I take?

I have a demyelinating brain disease confirmed by mri.  What precautions or life changes should I take?

Minimize stresses: So sorry to hear that as such conditions can be very difficult and scary, as well as devastating. However, some can also not progress, or even stabilize. Avoid as many stresses in your life as you can. This includes tobacco, alcohol and drugs, as well as social stress. Avoid dehydration. Get plenty of restful sleep, stay fit. Stay hopeful. Enjoy your life, personal and professional as + attitude helps. ...Read more

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What to do if I have chronic demyelinating brain disease confirmed by MRI what precautions should I take?

What to do if I have chronic demyelinating brain disease confirmed by MRI what precautions should I take?

Several: Multiple sclerosis can impair neurological functions; depending on what lesions you have or may acquire, it could affect your vision and your motor skills so that driving, for example, could be dangerous. You should talk this over with your neurologist to establish what you should or should not do. Also, the medications you may be prescribed may have some risks, especially infection. ...Read more

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18 y/o, given brain MRI without contrast (to rule out demyelinating disease) and the results were normal aside from some subtle nonspecific T2/FLAIR hyperintensity seen in the periatrial region bilaterally? What does this mean/should I be worried?

18 y/o, given brain MRI without contrast (to rule out demyelinating disease) and the results were normal aside from some subtle nonspecific T2/FLAIR hyperintensity seen in the periatrial region bilaterally? What does this mean/should I be worried?

Why ask here?: Presumably you didn't just pass an MRI facility & decided to go in and make an impulse purchase. A doctor had to order the MRI, one who knows you. It's his/her responsibility to interpret the MRI findings as part of your overall clinical picture, or if he/she can't, to find someone who can. The MRI isn't the patient; you are. ...Read more

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The CT scan brain results suggest that they a probability of demyelinating disease. Is this normal at my age?

The CT scan brain results suggest that they a probability of demyelinating disease. Is this normal at my age?

No, but...: Mri scans are more sensitive and specific for demyelination than ct scans. This means that not only are mris better at finding it when it's present, but not finding it on an MRI means that it's almost certainly absent. "Suggestive" findings of demyelination on a brain ct that is not seen on an MRI are generally treated as "false-positive." that gets into the science of testing (no room here). ...Read more

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What is dyemilinating disease & myasthenia gravis?

What is dyemilinating disease & myasthenia gravis?

Nerve disease: In patients with myasthenia, the acetylcholine receptor that helps form the neuromuscular junction is destroyed by the immune system. This causes nerves to be unable to trigger muscle contraction, leading to fatigable weakness. In demyelinationg disease, the myelin insulation surrounding the nerve is attacked by the immune system, disrupting signal transmission. ...Read more

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What is it if somebody has chronic inflammatory demyelinating polyneuropathy?

What is it if somebody has chronic inflammatory demyelinating polyneuropathy?

CIDP: This is an immune disorder of the peripheral nervous system, and involves an attack of the myelin coverings of mainly the motor nerves, but can be seen occasionally affecting sensory fibers as well. Cidp can be controlled with steroids or ivig, but relapses can occur, and lifelong treatment is often required. ...Read more

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What can you tell me about distal acquired demyelinating symmetric neuropathy?

What can you tell me about distal acquired demyelinating symmetric neuropathy?

A lot to say: There is a lot to say about this. First, how is the diagnosis made? A careful history, exam, and nerve conduction studies are needed. Testing for common causes of neuropathy are helpful- blood and urine tests for example. Sometimes, a nerve biopsy is a good idea. Is there a family history of this condition? Has there been any exposure to organic chemicals? These are important to answer. ...Read more

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Do most people who get chronic inflammatory demyelinating polyneuropathy have many symptoms?

Do most people who get chronic inflammatory demyelinating polyneuropathy have many symptoms?

Not subtle: CIDP is an immune neuropathy which may start insidiously, but rapidly develops into diffuse weakness causing difficulty with daily activities. Although the motor issues are usually the main manifestations, some tingling and numbness may occur, and variants may cause peripheral nerve pain, and imbalance. ...Read more

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Does anyone have really mild chronic inflammatory demyelinating polyneuropathy, making diagnosis uncertain?

Does anyone have really mild chronic inflammatory demyelinating polyneuropathy, making diagnosis uncertain?

CIDP: Not unique to have diagnostic challenges to confirm cidp. Most cases create significant weakness, but early on, it may be difficult to confirm, as even nerve biopsies may not be helpful. Best to check EMG for characteristic findings. Spinal fluid protein elevation may help. ...Read more

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I went for a nerve con. test, the results stated the ulnar nerve is blocked and a demyelinating lesion. Please explain what this means (D.Lesion)

I went for a nerve con. test, the results stated the ulnar nerve is blocked and a demyelinating lesion. Please explain what this means (D.Lesion)

Weakness: There is an electrical change in the nerve signal- conduction- across the ulnar nerve. The ulnar nerve provides signals to your forearm and hand. You may have had symptoms of sensory tingling at the elbow radiating to your 4, 5th finger and may have had weakness with flexion with these fingers also.
Demylinating means that the covering, myelin, is damaged. You must find the cause. ...Read more

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What does it mean to have demyelinating neuropathy?

What does it mean to have demyelinating neuropathy?

Neuropathy: The nerves are covered with an insultating material called myelin. Much like a telephone cable that has rubber covering it too acts as insulation "myelin" does the same for a nerve. If the myelin is weakened by disease or some pathological process one develops a demyelinating neuropathy of which there are many causes. ...Read more

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How effective are mri's in showing active current demyelinating lesions in ms?

How effective are mri's in showing active current demyelinating lesions in ms?

Very effective: MRI is indeed "Gold standard", and helps us make decisions regarding diagnosis and changes in therapy. Note you state diagnosis of MS, but do NOT find any disease modifying drug listed. Prednisone is fine for relapse, and IVIG might be used if you were pregnant, but neither helps control the disease chronically. Note fresh frozen plasma, and this too, has no role in MS therapy. ...Read more

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I hv demyelinating (not MS) located in pontomedular & hippocampus, with axonal damage in fronto pariental right-left. What function will be affected?

I hv demyelinating (not MS) located in pontomedular & hippocampus, with axonal damage in fronto pariental right-left. What function will be affected?

Too nonspecific: The description you provide is too nonspecific to correlate a localization to a function. More than likely your doctor ordered this test for a certain reason, not the other way around. Suggest you speak to your health care provider who understands your symptoms to get a further determination of correlation. ...Read more