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Doctor insights on: Lipoprotein Lipase

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Dr. Todd Igel
347 doctors shared insights

Lipase (Definition)

Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more


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What causes low lipase?

What causes low lipase?

No disease: Low lipase is not a pathologic state. You did not state the actual level and the normal ranges that the lab would have reported. ...Read more

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How do I reduce my lipase level?

Why is it elevated?: An elevated lipase is usually an indication of pancreatitis and that needs to be treated by a physician and is not an issue for self diagnosis or treatment. ...Read more

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Substrate name for lipase enzyme?

Olive oil: At least that's what we used for assays when i was doing a lot of clinical chemistry. Today kitmakers sell you "lipase substrate" which the physician need only do quality control on. I suspect it's olive oil. ...Read more

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What does an elevated lipase and amylase mean?

Can be pancreas infl: Amylase: enzyme made by pancreas and salivary glands. Elevation can be seen with pancreatitis, mumps, vomiting/bulimia sometimes with other GI (gallbladder, ulcer), gyn issues. Lipase is a somewhat more specific pancreatic enzyme. Mild elevations non specific, very high more specific marker of pancreatic inflammation. Kidney disease screws up the values. Incr. In cystic fibrosis, celiac, . ...Read more

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What could cause slightly elevated lipase levels?

How elevated?: It would help to know the number. Gall stones and alcohol are the common causes of elevated lipase. ...Read more

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Is there any way to consume lipase with orlistat?

Why?: Orlistat is a lipase blocker causing fatty diarrhea thereby leading to weight loss. Taking lipase will cause your fats to be absorbed offsetting the effect of orlistat. It makes no sense to take both together. ...Read more

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My lipase levels are elevated. What can this mean?

Maybe nothing: A mild elevation of serum lipase generally means nothing whatever. Even taking an Ibuprofen tablet may raise the level. The reference range is simply what most folks have. Lipase is assayed primarily to rule out acute pancreatitis, which is not a subtle disease and in which lipase is usually several times above the top of the reference range. ...Read more

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My lipase level came back as 20, should I be concerned?

No: Serum lipase level of 20 is normal. Why did you have the test done? All lab results need to be interpreted in the clinical context. ...Read more

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Lipase levels were mildly elevated; what would cause this?

High lipase levels: 33 F from Canada notes lipase levels mildly elevated and asks what could cause this. There are many things that can cause this including pancreatitis, gall bladder stone in pancreatic duct, meds, kidney disease, So you really need to ask the Dr who ordered it to interpret it for you as your team there knows you best. You can also google this. But I recommend uptodate.com 4 best source of med info ...Read more

Lipoprotein (Definition)

Lipoprotien is a combo of fat and protien the protien portion aiilows for the transport of the throughout the body and in to the cells of the tissues in the body. These can be measured with ...Read more