Top
20
Doctor insights on: Lipase Pancreatitis

Share
1

1
Idiopathic pancreatitis and sgot sgpt elevation?

Idiopathic pancreatitis and sgot sgpt elevation?

Workup: If available, get a proper genetic workup even if no one else in the family is affected. If your amylase is high but lipase normal and there is nothing on imaging pointing to the pancreas, this may be macroamylasemia. If the pancreatitis is real, checking the cystic fibrosis and trypsinogen loci is indicated. This may be one piece in the puzzle. Be persistent. ...Read more

Dr. Todd Igel
362 doctors shared insights

Lipase (Definition)

Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more


2

2
Do gall stones raise liver enzymes?

Do gall stones raise liver enzymes?

They may: It is not unusual for patients to have slight elevations in their liver enzymes with gall stones. This is probably caused by sub clinical inflammation in the gall bladder. Significant elevations are seen in acute cholecystitis and elevation of the bilirubin can be due due common duct stones with obstruction. ...Read more

4

4
I have elevated liver enzyme ast(sgot)412 ALT (sgpt) 317 GGT 186 dilation of the common bile duct 1 CM no gallbladder?

I have elevated liver enzyme ast(sgot)412 ALT (sgpt) 317  GGT 186 dilation of the common bile duct 1 CM no gallbladder?

Liver issue: Enzymes ast and alt are inside liver cells. When liver is injured by disease or medication, enzymes leak out, resulting in elevation. Can be due to many reasons, including medications like statins. An elevated GGT suggest biliary problems, but is not that specific. The normal common bile duct measures less than 0.8 cm, but after the gb is removed, can be 1cm. Complete history needed for this. ...Read more

See 1 more doctor answer
5

5
Idiopathic recurring pancreatitis, no alcoholism, gallstones, pain, high triglycerides. Only elevated amylase and lipase. What is next step?

Idiopathic recurring pancreatitis, no alcoholism, gallstones, pain, high triglycerides. Only elevated amylase and lipase. What is next step?

See your doctor soon: It is wise to see your doctor soon regarding this. Depending on how high your amylase and lipase are it could be acute or chronic pancreatitis, and considering that you're on medications and have a history of acute pancreatitis, it's even more important to see your doctor. Diet restrictions like low fat intake and fluid replacement and monitoring are needed to be done, so see dr. Asap. ...Read more

See 2 more doctor answers
6

6
Ultrasound:Normal sized pancreas with non-parencymal disease. Elevated lipase level 111. Vomiting, abdominal pain. Is it pancreatitis?

Ultrasound:Normal sized pancreas with non-parencymal disease. Elevated lipase level 111. Vomiting, abdominal pain. Is it pancreatitis?

Maybe: The fact that ultrasound didn't see anything does not mean you don't have pancreatitis . Laboratory data is needed to complete the work up for possible pancreatitis. Actually CT is better ...Read more

9

9
Normal lipase levels means healthy pancreas?

Normal lipase levels means healthy pancreas?

Not really: All it means is that you don't have pancreatitis at the time of the blood draw. If the pancreas were damaged by previous episodes of pancreatitis, the lipase would still be normal. ...Read more

10

10
What % of chronic or acute pancreatitis shows elevated Lipase or Amylase?

Acute tests: A 1998 study found that 100% of patients with acute pancreatitis had an elevated lipase, and 95% had an elevated amylase directly upon admission to the hospital. As their hospitalization continued, those values dropped off and so the tests would be less useful for diagnosis. ...Read more

12

12
How to diagnose pancreatic dysfunction? Amylase, lipase and insulin blood test?

History & physical: If the pancreas is inflamed or damaged, amylase and lipase are often up, and it's not subtle. If your pancreas isn't functioning properly, you'll be losing weight with no explanation and probably have diarrhea / steatorrhea. Your physician can check your stool for pancreatic enzymes. It's rare but with a suggestive history, a screen may show something that could respond to enzyme replacement. ...Read more

13

13
Calprotectin 95, ALT & AST chronically fluctuating elevated,sigmoidoscopy normal,MRCP normal, could it be IBD causing elevated liver enzyme ?

Calprotectin 95, ALT & AST chronically fluctuating elevated,sigmoidoscopy normal,MRCP normal, could it be IBD causing elevated liver enzyme ?

IBD complication AIH: The calprotectin level (I'm assuming it's a stool test) is rather high 4 ur age (normal is less than 51 ug/g stool), which seems confirm IBD but unfortunately didn't spare u a sigmoidoscopy. Caveat: proton pump inhibitors like Prilosec falsely elevate calprotectin. Nonetheless, a common complication of IBD is autoimmune hepatitis (AIH) which can cause fluctuating liver enzymes & damage. TTY GI do ...Read more

14

14
Chronic lipase elevation. Negative EUS. Possible causes?

Ignore it: Some people's lipase always runs high, and if the amylase is normal and there's nothing else to suggest pancreatitis on imaging or maldigestion / pancreatic insufficiency clinically, this is probably a false lead. ...Read more

16

16
Could prevacid (lansoprazole) elevate liver enzymes?

Yes, not common: Studies have shown that Prevacid (lansoprazole) has only rarely been associated with hepatic injury and elevated liver enzymes. Less than 1%. ...Read more

17

17
Could no gallbladder appendix cause pancreatitis?

Could no gallbladder appendix cause pancreatitis?

No: Appendix had nothing to do with pancreas. If the gallbladder had stones you could possible have a stone remaining on the bile duct. See your doctor. ...Read more

See 1 more doctor answer
18

18
Mild fatty liver parnchema and gallstone?

Mild fatty liver parnchema and gallstone?

Gall Stones: Fatty liver is a benign condition usually related to diet, however if it worsens it can become a condition called steatohepatitis. Watch your diet and it should improve. Gallstones are typically harmless unless a stone gets caught in a duct. Some people with a long family history of gallbladder problems get the gallbladder removed, but most people have gallstones all their life without problems ...Read more

19

19
Can pancreatitis occur without abnormal serum amylase level?

Yes: Though this is more likely with an acute flare in someone with chronic pancreatitis. Much of the pancreas may already be damaged/scarred/fibrosed in patients with chronic pancreatitis, so an acute injury may not cause much increase in serum amylase. ...Read more

20

20
On ursodeoxycholic acid, transaminases chronically fluctuating elevated ALT 50-200 AST 40-80.ALP 90-107. MRCP normal,fibroscan normal,what could it be?

On ursodeoxycholic acid, transaminases chronically fluctuating elevated ALT 50-200 AST 40-80.ALP 90-107. MRCP normal,fibroscan normal,what could it be?

Difficult question: Why the ursodiol? If for blood cholesterol, there may be better options (I don't see CF or PBC on your history). Sounds like you're getting a work up for the elevated enzymes. Consider a virtual consult with GI specialist for a thorough review of lab and imaging results. ...Read more

Dr. Ralph Layman
1,369 doctors shared insights

Pancreatitis (Definition)

Inflammation or infection of the pancreas (the organ positioned behind the lower ...Read more