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Workup: If available, get a proper genetic workup even if no one else in the family is affected. If your amylase is high but lipase normal and there is nothing on imaging pointing to the pancreas, this may be macroamylasemia. If the pancreatitis is real, checking the cystic fibrosis and trypsinogen loci is indicated. This may be one piece in the puzzle. Be persistent. ...Read more
Lipases, such as lipoprotein lipase and endothelial lipase, are enzymes that breakdown circulating triglycerides (tg). Specifically, lipases degrade tg rich lipoproteins including chylomicrons, very low density lipoprotein (vldl) and remnant particles produced by breakdown of chylomicron and vldl particles. Decreased lipase function leads to accumulation of ...Read more
They may: It is not unusual for patients to have slight elevations in their liver enzymes with gall stones. This is probably caused by sub clinical inflammation in the gall bladder. Significant elevations are seen in acute cholecystitis and elevation of the bilirubin can be due due common duct stones with obstruction. ...Read more
I have elevated liver enzyme ast(sgot)412 ALT (sgpt) 317 GGT 186 dilation of the common bile duct 1 CM no gallbladder?
Liver issue: Enzymes ast and alt are inside liver cells. When liver is injured by disease or medication, enzymes leak out, resulting in elevation. Can be due to many reasons, including medications like statins. An elevated GGT suggest biliary problems, but is not that specific. The normal common bile duct measures less than 0.8 cm, but after the gb is removed, can be 1cm. Complete history needed for this. ...Read moreSee 1 more doctor answer
Idiopathic recurring pancreatitis, no alcoholism, gallstones, pain, high triglycerides. Only elevated amylase and lipase. What is next step?
See your doctor soon: It is wise to see your doctor soon regarding this. Depending on how high your amylase and lipase are it could be acute or chronic pancreatitis, and considering that you're on medications and have a history of acute pancreatitis, it's even more important to see your doctor. Diet restrictions like low fat intake and fluid replacement and monitoring are needed to be done, so see dr. Asap. ...Read moreSee 2 more doctor answers
Ultrasound:Normal sized pancreas with non-parencymal disease. Elevated lipase level 111. Vomiting, abdominal pain. Is it pancreatitis?
Are pancreatic enzymes (amylase and lipase) always elevated if pancreatic cancer is present?? What about insulin blood level?
Acute tests: A 1998 study found that 100% of patients with acute pancreatitis had an elevated lipase, and 95% had an elevated amylase directly upon admission to the hospital. As their hospitalization continued, those values dropped off and so the tests would be less useful for diagnosis. ...Read more
History & physical: If the pancreas is inflamed or damaged, amylase and lipase are often up, and it's not subtle. If your pancreas isn't functioning properly, you'll be losing weight with no explanation and probably have diarrhea / steatorrhea. Your physician can check your stool for pancreatic enzymes. It's rare but with a suggestive history, a screen may show something that could respond to enzyme replacement. ...Read more
Calprotectin 95, ALT & AST chronically fluctuating elevated,sigmoidoscopy normal,MRCP normal, could it be IBD causing elevated liver enzyme ?
IBD complication AIH: The calprotectin level (I'm assuming it's a stool test) is rather high 4 ur age (normal is less than 51 ug/g stool), which seems confirm IBD but unfortunately didn't spare u a sigmoidoscopy. Caveat: proton pump inhibitors like Prilosec falsely elevate calprotectin. Nonetheless, a common complication of IBD is autoimmune hepatitis (AIH) which can cause fluctuating liver enzymes & damage. TTY GI do ...Read more
Gall Stones: Fatty liver is a benign condition usually related to diet, however if it worsens it can become a condition called steatohepatitis. Watch your diet and it should improve. Gallstones are typically harmless unless a stone gets caught in a duct. Some people with a long family history of gallbladder problems get the gallbladder removed, but most people have gallstones all their life without problems ...Read more
On ursodeoxycholic acid, transaminases chronically fluctuating elevated ALT 50-200 AST 40-80.ALP 90-107. MRCP normal,fibroscan normal,what could it be?
Difficult question: Why the ursodiol? If for blood cholesterol, there may be better options (I don't see CF or PBC on your history). Sounds like you're getting a work up for the elevated enzymes. Consider a virtual consult with GI specialist for a thorough review of lab and imaging results. ...Read more
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